Search Results - "Shah, Sameer B"

The Neuromuscular Junction: Roles in Aging and Neuromuscular Disease by Iyer, Shama R, Shah, Sameer B, Lovering, Richard M

“…The neuromuscular junction (NMJ) is a specialized synapse that bridges the motor neuron and the skeletal muscle fiber and is crucial for conversion of…”
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Skeletal Muscle Assessment Using Quantitative Ultrasound: A Narrative Review by Ashir, Aria, Jerban, Saeed, Barrère, Victor, Wu, Yuanshan, Shah, Sameer B, Andre, Michael P, Chang, Eric Y

“…Ultrasound (US) is an important imaging tool for skeletal muscle analysis. The advantages of US include point-of-care access, real-time imaging,…”
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Pre- and postsynaptic changes in the neuromuscular junction in dystrophic mice by Pratt, Stephen J P, Valencia, Ana P, Le, Gloribel K, Shah, Sameer B, Lovering, Richard M

“…Duchenne muscular dystrophy (DMD) is a devastating neuromuscular disease in which weakness, increased susceptibility to muscle injury, and inadequate repair…”
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Quantitative evaluation of rat sciatic nerve degeneration using high-frequency ultrasound by Wu, Yuanshan, Barrere, Victor, Han, Aiguo, Andre, Michael P., Orozco, Elisabeth, Cheng, Xin, Chang, Eric Y., Shah, Sameer B.

“…In this study, we evaluated the utility of using high-frequency ultrasound to non-invasively track the degenerative process in a rat model of peripheral nerve…”
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Effects of in vivo injury on the neuromuscular junction in healthy and dystrophic muscles by Pratt, Stephen J.P., Shah, Sameer B., Ward, Christopher W., Inacio, Mario P., Stains, Joseph P., Lovering, Richard M.

“…Key points •  Strength loss induced by lengthening contractions is typically attributed to damaged force‐bearing structures within skeletal muscle. Muscle…”
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Differential YAP nuclear signaling in healthy and dystrophic skeletal muscle by Iyer, Shama R, Shah, Sameer B, Ward, Christopher W, Stains, Joseph P, Spangenburg, Espen E, Folker, Eric S, Lovering, Richard M

“…Mechanical forces regulate muscle development, hypertrophy, and homeostasis. Force-transmitting structures allow mechanotransduction at the sarcolemma,…”
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Recovery of altered neuromuscular junction morphology and muscle function in mdx mice after injury by Pratt, Stephen J. P, Shah, Sameer B, Ward, Christopher W, Kerr, Jaclyn P, Stains, Joseph P, Lovering, Richard M

“…Duchenne muscular dystrophy (DMD) is a devastating neuromuscular disease in which weakness, increased susceptibility to muscle injury, and inadequate repair…”
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The role of the peripheral and central nervous systems in rotator cuff disease by Bachasson, Damien, PT, PhD, Singh, Anshuman, MD, Shah, Sameer B., PhD, Lane, John G., MD, Ward, Samuel R., PT, PhD

“…Rotator cuff (RC) disease is an extremely common condition associated with shoulder pain, reduced functional capacities, and impaired quality of life. It…”
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Misfolded SOD1 associated with motor neuron mitochondria alters mitochondrial shape and distribution prior to clinical onset by Vande Velde, Christine, McDonald, Karli K, Boukhedimi, Yasmin, McAlonis-Downes, Melissa, Lobsiger, Christian S, Bel Hadj, Samar, Zandona, Andre, Julien, Jean-Pierre, Shah, Sameer B, Cleveland, Don W

“…Mutations in superoxide dismutase (SOD1) are causative for inherited amyotrophic lateral sclerosis. A proportion of SOD1 mutant protein is misfolded onto the…”
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Quantitative ultrasound assessment of fatty infiltration of the rotator cuff muscles using backscatter coefficient by Toto-Brocchi, Marco, Wu, Yuanshan, Jerban, Saeed, Han, Aiguo, Andre, Michael, Shah, Sameer B., Chang, Eric Y.

“…Background To prospectively evaluate ultrasound backscatter coefficients (BSCs) of the supraspinatus and infraspinatus muscles and compare with Goutallier…”
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The two faces of pannexins: new roles in inflammation and repair by Makarenkova, Helen P, Shah, Sameer B, Shestopalov, Valery I

“…Pannexins belong to a family of ATP-release channels expressed in almost all cell types. An increasing body of literature on pannexins suggests that these…”
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Quantitative Ultrasound Techniques Used for Peripheral Nerve Assessment by Jerban, Saeed, Barrère, Victor, Andre, Michael, Chang, Eric Y, Shah, Sameer B

“…This review article describes quantitative ultrasound (QUS) techniques and summarizes their strengths and limitations when applied to peripheral nerves. A…”
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A guide to reducing adverse outcomes in rabbit models of sciatic nerve injury by Orozco, Elisabeth, Masuda, Koichi, Shah, Sameer B

“…Peripheral nerve damage can have debilitating consequences. Rabbit sciatic nerve transection models allow the effective evaluation of surgical repair…”
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Clinical potential of tension-lengthening strategies during nerve repair by Bazarek, Stanley, Brown, Justin, Shah, Sameer

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Novel Technologies to Address the Lower Motor Neuron Injury and Augment Reconstruction in Spinal Cord Injury by Bazarek, Stanley F, Krenn, Matthias J, Shah, Sameer B, Mandeville, Ross M, Brown, Justin M

“…Lower motor neuron (LMN) damage results in denervation of the associated muscle targets and is a significant yet under-appreciated component of spinal cord…”
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Regional Ulnar Nerve Strain Following Decompression and Anterior Subcutaneous Transposition in Patients With Cubital Tunnel Syndrome by Foran, Ian, MD, Vaz, Kenneth, MD, Sikora-Klak, Jakub, MD, Ward, Samuel R., PT, PhD, Hentzen, Eric R., MD, PhD, Shah, Sameer B., PhD

“…Purpose Simple decompression and anterior subcutaneous transposition are effective surgical interventions for cubital tunnel syndrome and yield similarly…”
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Ultrasound attenuation of cortical bone correlates with biomechanical, microstructural, and compositional properties by Jerban, Saeed, Barrere, Victor, Namiranian, Behnam, Wu, Yuanshan, Alenezi, Salem, Dorthe, Erik, Dlima, Darryl, Shah, Sameer B., Chung, Christine B., Du, Jiang, Andre, Michael P., Chang, Eric Y.

“…Background We investigated the relationship of two commonly used quantitative ultrasound (QUS) parameters, speed of sound (SoS) and attenuation coefficient ( α…”
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Pannexin 1 Modulates Axonal Growth in Mouse Peripheral Nerves by Horton, Steven M, Luna Lopez, Carlos, Blevins, Elisabeth, Howarth, Holly, Weisberg, Jake, Shestopalov, Valery I, Makarenkova, Helen P, Shah, Sameer B

“…The pannexin family of channels consists of three members-pannexin-1 (Panx1), pannexin-2 (Panx2), and pannexin-3 (Panx3) that enable the exchange of…”
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Redistribution of nerve strain enables end-to-end repair under tension without inhibiting nerve regeneration by Howarth, Holly, Alaziz, Turki, Nicolds, Brogan, O'Connor, Shawn, Shah, Sameer

“…End-to-end repair under no or low tension leads to improved outcomes for transected nerves with short gaps, compared to repairs with a graft. However, grafts…”
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Heads Up! Interlinked Amyloidogenic and Axonal Transport Pathways in Concussion-Induced Neurodegeneration by Almenar-Queralt, Angels, dos Santos Chaves, Rodrigo, Kwon, Ester J., Shah, Sameer B

“…Mild traumatic brain injury (mTBI), a condition in which brain function is transiently disrupted by a mechanical force, is a major risk factor for developing…”
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