Search Results - "Shah, Osama"

Systems approach for congruence and selection of cancer models towards precision medicine by Zou, Jian, Shah, Osama, Chiu, Yu-Chiao, Ma, Tianzhou, Atkinson, Jennifer M, Oesterreich, Steffi, Lee, Adrian V, Tseng, George C

“…Cancer models are instrumental as a substitute for human studies and to expedite basic, translational, and clinical cancer research. For a given cancer type, a…”
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Targeted mutation detection in breast cancer using MammaSeq by Smith, Nicholas G, Gyanchandani, Rekha, Shah, Osama S, Gurda, Grzegorz T, Lucas, Peter C, Hartmaier, Ryan J, Brufsky, Adam M, Puhalla, Shannon, Bahreini, Amir, Kota, Karthik, Wald, Abigail I, Nikiforov, Yuri E, Nikiforova, Marina N, Oesterreich, Steffi, Lee, Adrian V

“…Breast cancer is the most common invasive cancer among women worldwide. Next-generation sequencing (NGS) has revolutionized the study of cancer across research…”
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International survey on invasive lobular breast cancer identifies priority research questions by Oesterreich, Steffi, Pate, Leigh, Lee, Adrian V., Chen, Fangyuan, Jankowitz, Rachel C., Mukhtar, Rita, Metzger, Otto, Sikora, Matthew J., Li, Christopher I., Sotiriou, Christos, Shah, Osama S., Koorman, Thijs, Ulaner, Gary, Reis-Filho, Jorge S., Davidson, Nancy M., Van Baelen, Karen, Hutcheson, Laurie, Freeney, Siobhan, Migyanka, Flora, Turner, Claire, Derksen, Patrick, Bear, Todd, Desmedt, Christine

“…There is growing awareness of the unique etiology, biology, and clinical presentation of invasive lobular breast cancer (ILC), but additional research is…”
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Transcriptomic analysis identifies enrichment of cAMP/PKA/CREB signaling in invasive lobular breast cancer by Puthanmadhom Narayanan, Susrutha, Wedn, Abdalla M, Shah, Osama Shiraz, Chen, Jian, Brown, Daniel D, McAuliffe, Priscilla F, Oesterreich, Steffi, Lee, Adrian V

“…Invasive lobular breast cancer (ILC) is the most common special type of breast cancer and has unique clinicopathological and molecular hallmarks that…”
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A Personalized Therapeutics Approach Using an In Silico Drosophila Patient Model Reveals Optimal Chemo- and Targeted Therapy Combinations for Colorectal Cancer by Gondal, Mahnoor Naseer, Butt, Rida Nasir, Shah, Osama Shiraz, Sultan, Muhammad Umer, Mustafa, Ghulam, Nasir, Zainab, Hussain, Risham, Khawar, Huma, Qazi, Romena, Tariq, Muhammad, Faisal, Amir, Chaudhary, Safee Ullah

“…In silico models of biomolecular regulation in cancer, annotated with patient-specific gene expression data, can aid in the development of novel personalized…”
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ATLANTIS - Attractor Landscape Analysis Toolbox for Cell Fate Discovery and Reprogramming by Shah, Osama Shiraz, Chaudhary, Muhammad Faizyab Ali, Awan, Hira Anees, Fatima, Fizza, Arshad, Zainab, Amina, Bibi, Ahmed, Maria, Hameed, Hadia, Furqan, Muhammad, Khalid, Shareef, Faisal, Amir, Chaudhary, Safee Ullah

“…Boolean modelling of biological networks is a well-established technique for abstracting dynamical biomolecular regulation in cells. Specifically, decoding…”
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Outcomes After Sentinel Lymph Node Biopsy and Radiotherapy in Older Women With Early-Stage, Estrogen Receptor-Positive Breast Cancer by Carleton, Neil, Zou, Jian, Fang, Yusi, Koscumb, Stephen E, Shah, Osama Shiraz, Chen, Fangyuan, Beriwal, Sushil, Diego, Emilia J, Brufsky, Adam M, Oesterreich, Steffi, Shapiro, Steven D, Ferris, Robert, Emens, Leisha A, Tseng, George, Marroquin, Oscar C, Lee, Adrian V, McAuliffe, Priscilla F

“…Overtreatment of early-stage breast cancer with favorable tumor biology in older patients may be harmful without affecting recurrence and survival. Guidelines…”
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Abstract P3-06-15: Identifying genomic alterations in stage IV breast cancer patients using MammaSeq: An international collaborative study by Soran, Atilla, Sahin, Mustafa, Ugras, Serdar, Celik, Esin, Shah, Osama Shiraz, Lucas, Peter C, Lee, Adrian V

“…Background: Identification of genomic alterations present in cancer patients can aid in improving cancer diagnosis and prognosis. In this study, we aimed to…”
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Mixed invasive ductal lobular carcinoma is clinically and pathologically more similar to invasive lobular than ductal carcinoma by Nasrazadani, Azadeh, Li, Yujia, Fang, Yusi, Shah, Osama, Atkinson, Jennifer M., Lee, Joanna S., McAuliffe, Priscilla F., Bhargava, Rohit, Tseng, George, Lee, Adrian V., Lucas, Peter C., Oesterreich, Steffi, Wolmark, Norman

“…Background Mixed invasive ductal lobular carcinoma (mDLC) remains a poorly understood subtype of breast cancer composed of coexisting ductal and lobular…”
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Abstract PS7-15: Mixed invasive ductal lobular carcinomas (mDLC) are clinically more similar to invasive lobular carcinoma (ILC) than to invasive ductal carcinoma (IDC) by Nasrazadani, Azadeh, Li, Yujia, Fang, Yusi, Shah, Osama, Atkinson, Jennifer M, Lee, Joanna S, McAuliffe, Priscilla F, Lee, Adrian V, Tseng, George, Lucas, Peter, Oesterreich, Steffi, Wolmark, Norman

“…Clinicopathologic differences between histological subtypes of invasive breast cancer are increasingly being appreciated. Mixed invasive ductal lobular…”
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Spatial molecular profiling of mixed invasive ductal and lobular breast cancers reveals heterogeneity in intrinsic molecular subtypes, oncogenic signatures, and mutations by Shah, Osama Shiraz, Nasrazadani, Azadeh, Foldi, Julia, Atkinson, Jennifer M, Kleer, Celina G, McAuliffe, Priscilla F, Johnston, Tyler J, Stallaert, Wayne, da Silva, Edaise M, Selenica, Pier, Dopeso, Higinio, Pareja, Fresia, Mandelker, Diana, Weigelt, Britta, Reis-Filho, Jorge S, Bhargava, Rohit, Lucas, Peter C, Lee, Adrian V, Oesterreich, Steffi

“…Mixed invasive ductal and lobular carcinoma (MDLC) is a rare histologic subtype of breast cancer displaying both E-cadherin positive ductal and E-cadherin…”
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Abstract P5-12-03: Wcrc-25: A novel luminal invasive lobular carcinoma cell line model by Elangovan, Ashuvinee, Bossart, Emily A, Basudan, Ahmed, Tasdemir, Nilgun, Shah, Osama Shiraz, Ding, Kai, Meier, Carolin, Heim, Tanya, Miller, Lori, Liu, Tiantong, Puhalla, Shannon L, Gurda, Grzegorz, Lucas, Peter C, McAuliffe, Priscilla F, Atkinson, Jennifer M, Lee, Adrian V, Oesterreich, Steffi

“…Breast cancer is categorized by the molecular and histologic presentation of the tumor; with the major histologic subtypes observed in patients being Invasive…”
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Single-cell RNA-sequencing of human spleens reveals an IDO-1+ tolerogenic dendritic cell subset in pancreatic cancer patients that is absent in normal individuals by Mundry, Clara S., Triplett, Aleata A., Shah, Osama Shiraz, Chaitankar, Vijender, McAndrews, Kyle L., Ly, Quan P., Cox, Jesse L., Eberle, Kirsten C., Mehla, Kamiya, Swanson, Benjamin J., Lazenby, Audrey, Klute, Kelsey A., Grandgenett, Paul M., Hollingsworth, Michael A.

“…Local and systemic immunosuppression are prominent features of pancreatic cancer, rendering anti-tumor effector cells inactive and immunotherapeutic approaches…”
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Abstract PS19-06: Role of the calcium-sensing receptor (CaSR) in invasive lobular breast carcinoma metastasis to the ovary by Qin, Ye, Savariau, Laura, Basudan, Ahmed Mohammed, Shah, Osama, Li, Zheqi, Liu, Tiantong, Tasdemir, Nilgun, Coffman, Lan, Elishaev, Esther, Atkinson, Jennifer M, Lucas, Peter, Lee, Adrian V, Oesterreich, Steffi

“…Invasive lobular carcinoma (ILC) is the second most common histological subtype of breast cancer, after the more common invasive ductal carcinoma (IDC). ILC…”
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Abstract PS1-10: Outcomes after sentinel lymph node biopsy and radiation therapy in women over 70 years old with ER+, HER2-, clinically node negative breast cancer by McAuliffe, Priscilla F, Carleton, Neil M, Zou, Jian, Fang, Yusi, Koscumb, Stephen E, Shah, Osama, Chen, Fangyuan, Beriwal, Sushil, Diego, Emilia J, Brufsky, Adam M, Oesterreich, Steffi, Shapiro, Steve D, Ferris, Robert, Emens, Leisha A, Tseng, George, Marroquin, Oscar C, Lee, Adrian V

“…Overtreatment of early-stage breast cancer with favorable tumor biology in elderly patients can result in higher rates of complications and morbidities without…”
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Identifying Genomic Alterations in Patients With Stage IV Breast Cancer Using MammaSeq: An International Collaborative Study by Shah, Osama Shiraz, Soran, Atilla, Sahin, Mustafa, Knapick, Beth A., Ugras, Serdar, Celik, Esin, Lucas, Peter C., Lee, Adrian V.

“…Identification of genomic alterations present in cancer patients may aid in cancer diagnosis, prognosis and therapeutic target discovery. In this study, we…”
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Abstract PD4-07: PD4-07 Uncovering molecular heterogeneity of mixed ductal and lobular carcinoma using digital spatial profiling by Shah, Osama Shiraz, Nasrazadani, Azadeh, Atkinson, Jennifer M., Kleer, Celina, McAuliffe, Priscilla F., Bhargava, Rohit, Reis-Filho, Jorge, Lucas, Peter C., LEE, ADRIAN V., Oesterreich, Steffi

“…Background Mixed invasive ductal and lobular carcinoma (mDLC) is a rare special subtype (3-6%, ~10,000 cases/annually in US) of invasive breast cancer with…”
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Reactive Power Compensation Utilizing FACTS Devices by Shah, Syed Osama, Arshad, Ammar, Alam, Shahid

“…Efficient control of reactive power flow is required to maintain a stable system operation. Insufficient reactive power support may lead to system instability,…”
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