Search Results - "Shah, N Sarita"

Transmission of Extensively Drug-Resistant Tuberculosis in South Africa by Shah, N. Sarita, Auld, Sara C, Brust, James C.M, Mathema, Barun, Ismail, Nazir, Moodley, Pravi, Mlisana, Koleka, Allana, Salim, Campbell, Angela, Mthiyane, Thuli, Morris, Natashia, Mpangase, Primrose, van der Meulen, Hermina, Omar, Shaheed V, Brown, Tyler S, Narechania, Apurva, Shaskina, Elena, Kapwata, Thandi, Kreiswirth, Barry, Gandhi, Neel R

“…This study from South Africa showed that extensively drug-resistant tuberculosis, an emerging global public health threat, is largely associated with…”
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Approaches to tuberculosis screening and diagnosis in people with HIV in resource-limited settings by Reid, Michael JA, MRCP, Shah, N Sarita, MD

“…Summary Tuberculosis is the main cause of morbidity and mortality in people living with HIV/AIDS worldwide. Early diagnosis and treatment is essential to…”
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Yield of Contact Investigations in Households of Patients With Drug-Resistant Tuberculosis: Systematic Review and Meta-Analysis by Shah, N. Sarita, Yuen, Courtney M., Heo, Moonseong, Tolman, Arielle W., Becerra, Mercedes C.

“…Contact investigations among individuals living with drug-susceptible tuberculosis patients (source cases) have shown a high yield of tuberculosis disease and…”
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Global progress and gaps in tuberculosis screening and treatment among people with HIV: experience from 32 countries by Peterson, Meaghan, Sarita Shah, N., Smith-Jeffcoat, Sarah E., Nichols, Catherine, Fukunaga, Rena, Al-Samarrai, Teeb, MacNeil, Adam

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HIV Coinfection in Multidrug- and Extensively Drug-Resistant Tuberculosis Results in High Early Mortality by Gandhi, Neel R, Shah, N. Sarita, Andrews, Jason R, Vella, Venanzio, Moll, Anthony P, Scott, Michelle, Weissman, Darren, Marra, Claudio, Lalloo, Umesh G, Friedland, Gerald H, on behalf of Tugela Ferry Care and Research (TF CARES) Collaboration

“…The multidrug-resistant (MDR) and extensively drug-resistant (XDR) tuberculosis (TB) epidemics are rapidly expanding in South Africa. Our initial report of…”
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A new era for treatment of drug-resistant tuberculosis by Gandhi, Neel R, Brust, James C M, Shah, N Sarita

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Treatment outcomes among patients with multidrug-resistant tuberculosis: systematic review and meta-analysis by Orenstein, Evan W, BS, Basu, Sanjay, PhD, Shah, N Sarita, MD, Andrews, Jason R, MD, Friedland, Gerald H, MD, Moll, Anthony P, MBChB, Gandhi, Neel R, MD, Galvani, Alison P, PhD

“…Summary Multidrug-resistant (MDR) tuberculosis is a growing clinical and public-health concern. To evaluate existing evidence regarding treatment regimens for…”
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Factors associated with prevalent Mycobacterium tuberculosis infection and disease among adolescents and adults exposed to rifampin-resistant tuberculosis in the household by Kim, Soyeon, Hesseling, Anneke C, Wu, Xingye, Hughes, Michael D, Shah, N Sarita, Gaikwad, Sanjay, Kumarasamy, Nishi, Mitchell, Erika, Leon, Mey, Gonzales, Pedro, Badal-Faesen, Sharlaa, Lourens, Madeleine, Nerette, Sandy, Shenje, Justin, de Koker, Petra, Nedsuwan, Supalert, Mohapi, Lerato, Chakalisa, Unoda A, Mngqbisa, Rosie, Escada, Rodrigo Otávio da Silva, Ouma, Samuel, Heckman, Barbara, Naini, Linda, Gupta, Amita, Swindells, Susan, Churchyard, Gavin

“…Understanding factors associated with prevalent Mycobacterium tuberculosis infection and prevalent TB disease in household contacts of patients with…”
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Nosocomial Transmission of Extensively Drug-Resistant Tuberculosis in a Rural Hospital in South Africa by Gandhi, Neel R., Weissman, Darren, Moodley, Prashini, Ramathal, Melissa, Elson, Inga, Kreiswirth, Barry N., Mathema, Barun, Shashkina, Elena, Rothenberg, Richard, Moll, Anthony P., Friedland, Gerald, Sturm, A. Willem, Shah, N. Sarita

“…Background. Extensively drug-resistant tuberculosis (XDR-tuberculosis) is a global public health threat, but few data exist elucidating factors driving this…”
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Extensively drug-resistant tuberculosis in South Africa: genomic evidence supporting transmission in communities by Auld, Sara C, Shah, N Sarita, Mathema, Barun, Brown, Tyler S, Ismail, Nazir, Omar, Shaheed Vally, Brust, James C M, Nelson, Kristin N, Allana, Salim, Campbell, Angela, Mlisana, Koleka, Moodley, Pravi, Gandhi, Neel R

“…Despite evidence that transmission is driving an extensively drug-resistant TB (XDR-TB) epidemic, our understanding of where and between whom transmission…”
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TCA cycle remodeling drives proinflammatory signaling in humans with pulmonary tuberculosis by Collins, Jeffrey M, Jones, Dean P, Sharma, Ashish, Khadka, Manoj, Liu, Ken H, Kempker, Russell R, Prideaux, Brendan, Maner-Smith, Kristal, Tukvadze, Nestani, Shah, N. Sarita, Brust, James C. M, Sékaly, Rafick-Pierre, Gandhi, Neel R, Blumberg, Henry M, Ortlund, Eric A, Ziegler, Thomas R

“…The metabolic signaling pathways that drive pathologic tissue inflammation and damage in humans with pulmonary tuberculosis (TB) are not well understood. Using…”
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Extensively Drug-Resistant Tuberculosis in the United States, 1993-2007 by Shah, N. Sarita, Pratt, Robert, Armstrong, Lori, Robison, Valerie, Castro, Kenneth G, Cegielski, J. Peter

“…CONTEXT Worldwide emergence of extensively drug-resistant tuberculosis (XDR-TB) has raised global public health concern, given the limited therapy options and…”
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Treatment Outcomes in Global Systematic Review and Patient Meta-Analysis of Children with Extensively Drug-Resistant Tuberculosis by Osman, Muhammad, Harausz, Elizabeth P, Garcia-Prats, Anthony J, Schaaf, H Simon, Moore, Brittany K, Hicks, Robert M, Achar, Jay, Amanullah, Farhana, Barry, Pennan, Becerra, Mercedes, Chiotan, Domnica I, Drobac, Peter C, Flood, Jennifer, Furin, Jennifer, Gegia, Medea, Isaakidis, Petros, Mariandyshev, Andrei, Ozere, Iveta, Shah, N Sarita, Skrahina, Alena, Yablokova, Elena, Seddon, James A, Hesseling, Anneke C

“…Extensively drug-resistant tuberculosis (XDR TB) has extremely poor treatment outcomes in adults. Limited data are available for children. We report on…”
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Multidrug-Resistant and Extensively Drug-Resistant Tuberculosis: Implications for the HIV Epidemic and Antiretroviral Therapy Rollout in South Africa by Andrews, Jason R, Sarita Shah, N, Gandhi, Neel, Moll, Tony, Friedland, Gerald

“…Drug-resistant tuberculosis (TB) is emerging as a major clinical and public health challenge in areas of sub-Saharan Africa where there is a high prevalence of…”
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Worldwide emergence of extensively drug-resistant tuberculosis by Shah, N Sarita, Wright, Abigail, Bai, Gill-Han, Barrera, Lucia, Boulahbal, Fadila, Martín-Casabona, Nuria, Drobniewski, Francis, Gilpin, Chris, Havelková, Marta, Lepe, Rosario, Lumb, Richard, Metchock, Beverly, Portaels, Françoise, Rodrigues, Maria Filomena, Rüsch-Gerdes, Sabine, Van Deun, Armand, Vincent, Veronique, Laserson, Kayla, Wells, Charles, Cegielski, J Peter

“…Mycobacterium tuberculosis strains that are resistant to an increasing number of second-line drugs used to treat multidrug-resistant tuberculosis (MDR TB) are…”
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Schistosoma mansoni Infection Is Associated With a Higher Probability of Tuberculosis Disease in HIV-Infected Adults in Kenya by McLaughlin, Taryn A., Nizam, Azhar, Hayara, Felix Odhiambo, Ouma, Gregory Sadat, Campbell, Angela, Khayumbi, Jeremiah, Ongalo, Joshua, Ouma, Samuel Gurrion, Shah, N. Sarita, Altman, John D., Kaushal, Deepak, Rengarajan, Jyothi, Ernst, Joel D., Blumberg, Henry M., Waller, Lance A., Gandhi, Neel R., Day, Cheryl L., Benkeser, David

“…BACKGROUND:Helminth infections can modulate immunity to Mycobacterium tuberculosis (Mtb). However, the effect of helminths, including Schistosoma mansoni (SM),…”
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Modeling Missing Cases and Transmission Links in Networks of Extensively Drug-Resistant Tuberculosis in KwaZulu-Natal, South Africa by Nelson, Kristin N, Gandhi, Neel R, Mathema, Barun, Lopman, Benjamin A, Brust, James C M, Auld, Sara C, Ismail, Nazir, Omar, Shaheed Vally, Brown, Tyler S, Allana, Salim, Campbell, Angie, Moodley, Pravi, Mlisana, Koleka, Shah, N Sarita, Jenness, Samuel M

“…Abstract Patterns of transmission of drug-resistant tuberculosis (TB) remain poorly understood, despite over half a million incident cases worldwide in 2017…”
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Social Mixing and Clinical Features Linked With Transmission in a Network of Extensively Drug-resistant Tuberculosis Cases in KwaZulu-Natal, South Africa by Nelson, Kristin N, Jenness, Samuel M, Mathema, Barun, Lopman, Benjamin A, Auld, Sara C, Shah, N Sarita, Brust, James C M, Ismail, Nazir, Omar, Shaheed Vally, Brown, Tyler S, Allana, Salim, Campbell, Angie, Moodley, Pravi, Mlisana, Koleka, Gandhi, Neel R

“…Abstract Background Tuberculosis (TB) is the leading infectious cause of death globally, and drug-resistant TB strains pose a serious threat to controlling the…”
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Exogenous Reinfection as a Cause of Multidrug-Resistant and Extensively Drug-Resistant Tuberculosis in Rural South Africa by Andrews, Jason R., Gandhi, Neel R., Moodley, Prashini, Shah, N. Sarita, Bohlken, Louise, Moll, Anthony P., Pillay, Manormoney, Friedland, Gerald, Sturm, A. Willem

“…Background. Multidrug-resistant (MDR) and extensively drug-resistant (XDR) tuberculosis (TB) are now major threats in areas of South Africa with a high…”
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pncA Gene Mutations Associated with Pyrazinamide Resistance in Drug-Resistant Tuberculosis, South Africa and Georgia by Allana, Salim, Shashkina, Elena, Mathema, Barun, Bablishvili, Nino, Tukvadze, Nestani, Shah, N Sarita, Kempker, Russell R, Blumberg, Henry M, Moodley, Pravi, Mlisana, Koleka, Brust, James C M, Gandhi, Neel R

“…Although pyrazinamide is commonly used for tuberculosis treatment, drug-susceptibility testing is not routinely available. We found polymorphisms in the pncA…”
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