Search Results - "Shah, Jai"

Bringing Clinical Staging to Youth Mental Health: From Concept to Operationalization (and Back Again) by Shah, Jai L

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Revitalizing the role of social determinants in mental health by Shah, Jai L.

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The “polyenviromic risk score”: Aggregating environmental risk factors predicts conversion to psychosis in familial high-risk subjects by Padmanabhan, Jaya L, Shah, Jai L, Tandon, Neeraj, Keshavan, Matcheri S

“…Abstract Background Young relatives of individuals with schizophrenia (i.e. youth at familial high-risk, FHR) are at increased risk of developing psychotic…”
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Moving From Islands of Order to a Sea of Chaos: Transitions out of Early Intervention Services for Psychosis by McIlwaine, Sarah, Fuhrer, Rebecca, Shah, Jai L

“…McIlwaine et al discuss the study by Jones et al which offers a qualitative exploration of matters relating to transfers between early intervention service for…”
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Unpacking the phenomenon of declining transition rates to first episode psychosis: The dyad of science and service reform in action by Daneault, Jean-Gabriel, Shah, Jai L.

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Much ado about much: Stress, dynamic biomarkers and HPA axis dysregulation along the trajectory to psychosis by Shah, Jai L, Malla, Ashok K

“…Abstract Objectives In the context of a stress–vulnerability framework, hyperactivation of the hypothalamic–pituitary–adrenal (HPA) axis is thought contribute…”
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Transdiagnostic clinical staging in youth mental health: a first international consensus statement by Shah, Jai L., Scott, Jan, McGorry, Patrick D., Cross, Shane P.M., Keshavan, Matcheri S., Nelson, Barnaby, Wood, Stephen J., Marwaha, Steven, Yung, Alison R., Scott, Elizabeth M., Öngür, Dost, Conus, Philippe, Henry, Chantal, Hickie, Ian B.

“…Recognizing that current frameworks for classification and treatment in psychiatry are inadequate, particularly for use in young people and early intervention…”
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Is the Clinical High-Risk State a Valid Concept? Retrospective Examination in a First-Episode Psychosis Sample by Shah, Jai L, Crawford, Anne, Mustafa, Sally S, Iyer, Srividya N, Joober, Ridha, Malla, Ashok K

“…Objective:One reason for worldwide interest in the clinical high-risk (CHR) state for psychosis is its potential as a target for prevention. However, the…”
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Combinations and Temporal Associations Among Precursor Symptoms Before a First Episode of Psychosis by Paquin, Vincent, Malla, Ashok K, Iyer, Srividya N, Lepage, Martin, Joober, Ridha, Shah, Jai L

“…Symptoms that precede a first episode of psychosis (FEP) can ideally be targeted by early intervention services with the aim of preventing or delaying…”
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Adipose tissue dysregulation at the onset of psychosis: Adipokines and social determinants of health by Veru-Lesmes, Franz, Guay, Stéphane, Shah, Jai L., Schmitz, Norbert, Giguère, Charles-Édouard, Joober, Ridha, Iyer, Srividya N., Malla, Ashok K.

“…•First-episode psychosis patients have significantly different adipokine blood levels.•Adipokine changes were observed with null or minimal exposure to…”
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Improving the Detection of Individuals at Clinical Risk for Psychosis in the Community, Primary and Secondary Care: An Integrated Evidence-Based Approach by Fusar-Poli, Paolo, Sullivan, Sarah A., Shah, Jai L., Uhlhaas, Peter J.

“…Background: The first rate-limiting step for improving outcomes of psychosis through preventive interventions in people at clinical high risk for psychosis…”
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Early intervention service systems for youth mental health: integrating pluripotentiality, clinical staging, and transdiagnostic lessons from early psychosis by Shah, Jai L, Jones, Nev, van Os, Jim, McGorry, Patrick D, Gülöksüz, Sinan

“…Challenges associated with operationalising services for the at-risk mental state for psychosis solely in that same diagnostic silo are increasingly well…”
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Joint-trajectories of clinical severity, social functioning and cannabis use in first-episode psychosis: A 5-year longitudinal study in 2 urban early intervention services by D'Andrea, Giuseppe, Ouellet-Plamondon, Clairélaine, Villeneuve, Marie, Shah, Jai L., Iyer, Srividya N., Abdel-Baki, Amal

“…•The role of cannabis use in first-episode psychosis may be complex and vary significantly across patients and over time.•Using 5-year longitudinal data, we…”
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Association of Pre-onset Subthreshold Psychotic Symptoms With Longitudinal Outcomes During Treatment of a First Episode of Psychosis by Rosengard, Rachel J, Malla, Ashok, Mustafa, Sally, Iyer, Srividya N, Joober, Ridha, Bodnar, Michael, Lepage, Martin, Shah, Jai L

“…The clinical high-risk state in psychosis is most often characterized by subthreshold psychotic symptoms (STPS) and represents a target for psychosis…”
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Clinical high at-risk mental state in young subjects accessing a mental disorder prevention service in Italy by Monego, Enrico, Cremonese, Carla, Gentili, Federica, Fusar-Poli, Paolo, Shah, Jai L, Solmi, Marco

“…•This is the first study applying clinical high at-risk state criteria in an external site.•We show that help-seeking adolescents and young adults meet…”
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Caught in the “NEET Trap”: The Intersection Between Vocational Inactivity and Disengagement From an Early Intervention Service for Psychosis by Maraj, Anika, Mustafa, Sally, Joober, Ridha, Malla, Ashok, Shah, Jai L, Iyer, Srividya N

“…Objective:Given the benefits of early intervention for psychosis and the social disengagement of youths not in education, employment, or training (NEET), this…”
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The Trier Social Stress Test in first episode psychosis patients: Impact of perceived stress, protective factors and childhood trauma by Seitz, Raffaela, Vracotas, Nadia, Bechard-Evans, Laura, King, Suzanne, Abadi, Sherezad, Joober, Ridha, Shah, Jai L., Malla, Ashok K., Pruessner, Marita

“…•First episode psychosis patients show reduced baseline cortisol levels during the TSST.•Cortisol increase following the TSST is intact in first episode…”
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Five Years of Youth Engagement with Kids Help Phone Canada (Part 1): Phone, Chat, Text, and Peer-to-Peer Service Usage Nationally, Provincially, and Over Time by Mughal, Sarah, McIlwaine, Sarah V, Swaroop, Sai, Simon, Alisa, Shah, Jai L

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Five Years of Youth Engagement with Kids Help Phone Canada (Part 2): Issues Discussed Over Phone, Chat, Text, and Peer-to-Peer Services by Age Range by Mughal, Sarah, McIlwaine, Sarah V, Swaroop, Sai, Simon, Alisa, Shah, Jai L

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Timing, Distribution, and Relationship Between Nonpsychotic and Subthreshold Psychotic Symptoms Prior to Emergence of a First Episode of Psychosis by Cupo, Lani, McIlwaine, Sarah V, Daneault, Jean-Gabriel, Malla, Ashok K, Iyer, Srividya N, Joober, Ridha, Shah, Jai L

“…Abstract Prospective population studies suggest that psychotic syndromes may be an emergent phenomenon—a function of severity and complexity of more common…”
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