Search Results - "Shah, Bhavik"

Rapid versus Delayed Stimulation of Feeding by the Endogenously Released AgRP Neuron Mediators GABA, NPY, and AgRP by Krashes, Michael J., Shah, Bhavik P., Koda, Shuichi, Lowell, Bradford B.

“…Agouti-related peptide (AgRP) neurons of the hypothalamus release a fast transmitter (GABA) in addition to neuropeptides (neuropeptide Y [NPY] and…”
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Fasting Activation of AgRP Neurons Requires NMDA Receptors and Involves Spinogenesis and Increased Excitatory Tone by Liu, Tiemin, Kong, Dong, Shah, Bhavik P., Ye, Chianping, Koda, Shuichi, Saunders, Arpiar, Ding, Jun B., Yang, Zongfang, Sabatini, Bernardo L., Lowell, Bradford B.

“…AgRP neuron activity drives feeding and weight gain whereas that of nearby POMC neurons does the opposite. However, the role of excitatory glutamatergic input…”
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Eco‐physiological portrait of a novel Pseudomonas sp. CSV86: an ideal host/candidate for metabolic engineering and bioremediation by Phale, Prashant S., Mohapatra, Balaram, Malhotra, Harshit, Shah, Bhavik A.

“…Summary Pseudomonas sp. CSV86, an Indian soil isolate, degrades wide range of aromatic compounds like naphthalene, benzoate and phenylpropanoids, amongst…”
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Polypharmacy, Adverse Drug Reactions, and Geriatric Syndromes by Shah, Bhavik M., PharmD, BCPS, Hajjar, Emily R., PharmD, BCPS, BCACP, CGP

“…The elderly are at risk for polypharmacy, which is associated with significant consequences such as adverse effects, medication nonadherence, drug-drug and…”
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A neural basis for melanocortin-4 receptor–regulated appetite by Garfield, Alastair S, Li, Chia, Madara, Joseph C, Shah, Bhavik P, Webber, Emily, Steger, Jennifer S, Campbell, John N, Gavrilova, Oksana, Lee, Charlotte E, Olson, David P, Elmquist, Joel K, Tannous, Bakhos A, Krashes, Michael J, Lowell, Bradford B

“…Melanocortin 4 receptors (MC4Rs) are critical to the promotion of homeostatic satiety. The authors established paraventricular hypothalamus (PVH)…”
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An excitatory paraventricular nucleus to AgRP neuron circuit that drives hunger by Krashes, Michael J., Shah, Bhavik P., Madara, Joseph C., Olson, David P., Strochlic, David E., Garfield, Alastair S., Vong, Linh, Pei, Hongjuan, Watabe-Uchida, Mitsuko, Uchida, Naoshige, Liberles, Stephen D., Lowell, Bradford B.

“…The AgRP-expressing neurons in the arcuate nucleus drive food-seeking behaviours during caloric restriction; a mouse study of monosynaptic retrograde rabies…”
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A Parabrachial-Hypothalamic Cholecystokinin Neurocircuit Controls Counterregulatory Responses to Hypoglycemia by Garfield, Alastair S., Shah, Bhavik P., Madara, Joseph C., Burke, Luke K., Patterson, Christa M., Flak, Jonathan, Neve, Rachael L., Evans, Mark L., Lowell, Bradford B., Myers, Martin G., Heisler, Lora K.

“…Hypoglycemia engenders an autonomically mediated counterregulatory (CR)-response that stimulates endogenous glucose production to maintain concentrations…”
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A rapidly acting glutamatergic ARC→PVH satiety circuit postsynaptically regulated by α-MSH by Fenselau, Henning, Campbell, John N, Verstegen, Anne M J, Madara, Joseph C, Xu, Jie, Shah, Bhavik P, Resch, Jon M, Yang, Zongfang, Mandelblat-Cerf, Yael, Livneh, Yoav, Lowell, Bradford B

“…Hunger-promoting AgRP neurons and satiety-promoting POMC neurons in the arcuate nucleus mediate homeostatic regulation of hunger. Yet a rapidly acting satiety…”
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Degradation strategies and associated regulatory mechanisms/features for aromatic compound metabolism in bacteria by Phale, Prashant S, Malhotra, Harshit, Shah, Bhavik A

“…As a result of anthropogenic activity, large number of recalcitrant aromatic compounds have been released into the environment. Consequently, microbial…”
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MC4R-expressing glutamatergic neurons in the paraventricular hypothalamus regulate feeding and are synaptically connected to the parabrachial nucleus by Shah, Bhavik P., Vong, Linh, Olson, David P., Koda, Shuichi, Krashes, Michael J., Ye, Chianping, Yang, Zongfang, Fuller, Patrick M., Elmquist, Joel K., Lowell, Bradford B.

“…Significance Both in rodents and humans, melanocortin-4 receptors (MC4Rs) suppress appetite and prevent obesity. Unfortunately, the underlying neural…”
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Dynamic GABAergic afferent modulation of AgRP neurons by Garfield, Alastair S, Shah, Bhavik P, Burgess, Christian R, Li, Monica M, Li, Chia, Steger, Jennifer S, Madara, Joseph C, Campbell, John N, Kroeger, Daniel, Scammell, Thomas E, Tannous, Bakhos A, Myers, Martin G, Andermann, Mark L, Krashes, Michael J, Lowell, Bradford B

“…AgRP neurons of the arcuate nucleus of the hypothalamus promote homeostatic feeding yet are rapidly suppressed by food-related sensory cues. The authors…”
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Low-dose infigratinib increases bone growth and corrects growth plate abnormalities in an achondroplasia mouse model by Demuynck, Benoit, Flipo, Justine, Kaci, Nabil, Dambkowski, Carl, Paull, Morgan, Muslimova, Elena, Shah, Bhavik P, Legeai-Mallet, Laurence

“…Achondroplasia (ACH), the most common form of disproportionate short stature, is caused by gain-of-function point mutations in fibroblast growth factor…”
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Advanced Penile Length Restoration Techniques to Optimize Penile Prosthesis Placement Outcomes by Shah, Bhavik B., Kent, Marissa, Valenzuela, Robert

“…The most common cause of patient dissatisfaction after penile prosthesis placement is penile shortening compared with one’s memory of a natural erection…”
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Variability in Assembly of Degradation Operons for Naphthalene and its derivative, Carbaryl, Suggests Mobilization through Horizontal Gene Transfer by Phale, Prashant S, Shah, Bhavik A, Malhotra, Harshit

“…In the biosphere, the largest biological laboratory, increased anthropogenic activities have led microbes to evolve and adapt to the changes occurring in the…”
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Tenofovir Alafenamide: A Review of Its Use in the Treatment of HIV-1 Infection by Gibson, Amanda K., Shah, Bhavik M., Nambiar, Puja H., Schafer, Jason J.

“…Objective: To review the pharmacology, efficacy, safety, and place in therapy for tenofovir alafenamide (TAF). Data Sources: A search using PubMed was…”
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The ‘qRBBB myocardial infarction’: Unwrapping an old enigma by Lanjewar, Charan P., Shah, Bhavik S., Sabnis, Girish R., Sharma, Achal, Kumar, Dhiraj

“…This single-center, prospective, observational study was conducted at a tertiary-care center over a span of two years. Patients presenting with acute…”
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Transient receptor potential channel type M5 is essential for fat taste by Liu, Pin, Shah, Bhavik P, Croasdell, Stephanie, Gilbertson, Timothy A

“…Until recently, dietary fat was considered to be tasteless, and its primary sensory attribute was believed to be its texture (Rolls et al., 1999; Verhagen et…”
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Dolutegravir: A New Integrase Strand Transfer Inhibitor for the Treatment of HIV by Shah, Bhavik M., Schafer, Jason J., DeSimone Jr, Joseph A.

“…The first two integrase strand transfer inhibitors (INSTIs) approved for treatment of patients infected with human immunodeficiency virus (HIV) were…”
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TRPM5 is critical for linoleic acid-induced CCK secretion from the enteroendocrine cell line, STC-1 by Shah, Bhavik P, Liu, Pin, Yu, Tian, Hansen, Dane R, Gilbertson, Timothy A

“…Fatty acid-induced stimulation of enteroendocrine cells leads to release of the hormones such as cholecystokinin (CCK) that contribute to satiety. Recently,…”
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Current Mechanistic and Pharmacodynamic Understanding of Melanocortin-4 Receptor Activation by Sharma, Shubh, Garfield, Alastair S, Shah, Bhavik, Kleyn, Patrick, Ichetovkin, Ilia, Moeller, Ida Hatoum, Mowrey, William R, Van der Ploeg, Lex H T

“…In this work we summarize our understanding of melanocortin 4 receptor (MC4R) pathway activation, aiming to define a safe and effective therapeutic targeting…”
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