Search Results - "Shafiq, Mohsin"

SFPQ and Tau: critical factors contributing to rapid progression of Alzheimer’s disease by Younas, Neelam, Zafar, Saima, Shafiq, Mohsin, Noor, Aneeqa, Siegert, Anna, Arora, Amandeep Singh, Galkin, Alexey, Zafar, Ayesha, Schmitz, Mathias, Stadelmann, Christine, Andreoletti, Olivier, Ferrer, Isidre, Zerr, Inga

“…Dysfunctional RNA-binding proteins (RBPs) have been implicated in several neurodegenerative disorders. Recently, this paradigm of RBPs has been extended to…”
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SWATH Mass Spectrometry-Based CSF Proteome Profile of GBA -Linked Parkinson's Disease Patients by Zafar, Saima, Noor, Aneeqa, Younas, Neelam, Shafiq, Mohsin, Schmitz, Matthias, Wurster, Isabel, Brockmann, Kathrin, Gasser, Thomas, Zerr, Inga

“…β-glucocerebrosidase ( )-associated mutations are a significant risk factor for Parkinson's disease (PD) that aggravate the disease pathology by upregulating…”
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Molecular Profiles of Amyloid-β Proteoforms in Typical and Rapidly Progressive Alzheimer’s Disease by Noor, Aneeqa, Zafar, Saima, Shafiq, Mohsin, Younas, Neelam, Siegert, Anna, Mann, Florian A., Kruss, Sebastian, Schmitz, Matthias, Dihazi, Hassan, Ferrer, Isidre, Zerr, Inga

“…The molecular determinants of atypical clinical variants of Alzheimer’s disease, including the recently discovered rapidly progressive Alzheimer’s disease…”
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Animal TSEs and public health: What remains of past lessons? by Zafar, Saima, Shafiq, Mohsin, Andréoletti, Olivier, Zerr, Inga

“…Transmissible spongiform encephalopathies (TSEs) or prion diseases of animals include scrapie in sheep and goat, chronic wasting disease (CWD) in cervids…”
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Transgenic Overexpression of the Disordered Prion Protein N1 Fragment in Mice Does Not Protect Against Neurodegenerative Diseases Due to Impaired ER Translocation by Mohammadi, Behnam, Linsenmeier, Luise, Shafiq, Mohsin, Puig, Berta, Galliciotti, Giovanna, Giudici, Camilla, Willem, Michael, Eden, Thomas, Koch-Nolte, Friedrich, Lin, Yu-Hsuan, Tatzelt, Jörg, Glatzel, Markus, Altmeppen, Hermann C.

“…The structurally disordered N-terminal half of the prion protein (PrP C ) is constitutively released into the extracellular space by an endogenous proteolytic…”
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Prion protein oligomers cause neuronal cytoskeletal damage in rapidly progressive Alzheimer's disease by Shafiq, Mohsin, Zafar, Saima, Younas, Neelam, Noor, Aneeqa, Puig, Berta, Altmeppen, Hermann Clemens, Schmitz, Matthias, Matschke, Jakob, Ferrer, Isidre, Glatzel, Markus, Zerr, Inga

“…High-density oligomers of the prion protein (HDPs) have previously been identified in brain tissues of patients with rapidly progressive Alzheimer's disease…”
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Inducing prion protein shedding as a neuroprotective and regenerative approach in pathological conditions of the brain: from theory to facts by Matamoros-Angles, Andreu, Mohammadi, Behnam, Song, Feizhi, Shafiq, Mohsin, Brenna, Santra, Puig, Berta, Glatzel, Markus, Altmeppen, Hermann

“…In the last decades, the role of the prion protein (PrP) in neurodegenerative diseases has been intensively investigated, initially in prion diseases of humans…”
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NeuroCOVID: Insights into Neuroinvasion and Pathophysiology by Matschke, Jakob, Krasemann, Susanne, Altmeppen, Hermann C., Shafiq, Mohsin, Glatzel, Markus

“…Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), may lead to acute and chronic neurological…”
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Quantification of CSF biomarkers using an electrochemiluminescence-based detection system in the differential diagnosis of AD and sCJD by Llorens, Franc, Kruse, Niels, Schmitz, Matthias, Shafiq, Mohsin, da Cunha, José Eriton Gomes, Gotzman, Nadine, Zafar, Saima, Thune, Katrin, de Oliveira, João Ricardo Mendes, Mollenhauer, Brit, Zerr, Inga

“…The identification of reliable diagnostic tools for the differential diagnosis between sporadic Creutzfeldt–Jakob Disease (sCJD) and Alzheimer’s disease (AD)…”
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Comment on “Extracellular Vesicles Slow Down Aβ(1–42) Aggregation by Interfering with the Amyloid Fibril Elongation Step” by Shafiq, Mohsin, Matamoros-Angles, Andreu, Meister, Sussane Caroline, Glatzel, Markus

“…Halipi et al. explored the impact of extracellular vesicles (EVs) on amyloid-β (Aβ) aggregation. They concluded that EVs reduce Aβ aggregation, as seen by…”
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Anchorless risk or released benefit? An updated view on the ADAM10-mediated shedding of the prion protein by Mohammadi, Behnam, Song, Feizhi, Matamoros-Angles, Andreu, Shafiq, Mohsin, Damme, Markus, Puig, Berta, Glatzel, Markus, Altmeppen, Hermann Clemens

“…The prion protein (PrP) is a broadly expressed glycoprotein linked with a multitude of (suggested) biological and pathological implications. Some of these…”
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Association of IRGM promoter region polymorphisms and haplotype with pulmonary tuberculosis in Pakistani (Punjab) population by Zafar, Ayesha, Shafiq, Mohsin, Ali, Basharat, Sadee, Wolfgang, Shakoori, Abdul Rauf, Shakoori, Farah Rauf

“…Single nucleotide polymorphisms (SNPs) in IRGM are reported to affect Mycobacterium tuberculosis (M.tb) degradation pathway. Here, we aim to screen…”
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The prion protein and its ligands: Insights into structure-function relationships by Shafiq, Mohsin, Da Vela, Stefano, Amin, Ladan, Younas, Neelam, Harris, David A, Zerr, Inga, Altmeppen, Hermann C, Svergun, Dmitri, Glatzel, Markus

“…The prion protein is a multifunctional protein that exists in at least two different folding states. It is subject to diverse proteolytic processing steps that…”
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Proteomic characterization of small vessel pathology in PSEN1 E280A familial Alzheimer’s disease by Littau, Jessica Lisa, Amri, Yassir El, Villalba‐Moreno, Nelson David, Shafiq, Mohsin, Lopera, Francisco, ‐Lanau, Andres Villegas, Sepulveda‐Falla, Diego

“…Background Vascular pathology is a main contributor to Alzheimer’s disease (AD) progression and severity. We have previously characterized vascular pathology…”
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Vagus nerve inflammation contributes to dysautonomia in COVID-19 by Woo, Marcel S., Shafiq, Mohsin, Fitzek, Antonia, Dottermusch, Matthias, Altmeppen, Hermann, Mohammadi, Behnam, Mayer, Christina, Bal, Lukas C., Raich, Lukas, Matschke, Jakob, Krasemann, Susanne, Pfefferle, Susanne, Brehm, Thomas Theo, Lütgehetmann, Marc, Schädler, Julia, Addo, Marylyn M., Schulze zur Wiesch, Julian, Ondruschka, Benjamin, Friese, Manuel A., Glatzel, Markus

“…Dysautonomia has substantially impacted acute COVID-19 severity as well as symptom burden after recovery from COVID-19 (long COVID), yet the underlying causes…”
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Animal TSEs and public health: What remains of past lessons? by Zafar, Saima, Shafiq, Mohsin, Andréoletti, Olivier, Zerr, Inga

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A pipeline for time-resolved small-angle X-ray scattering data analysis on amyloid fibrils formation in solution by Cheremnykh, Taja, Shafiq, Mohsin, Da Vela, Stefano, Glatzel, Markus, Svergun, Dmitri

“…Abstract only…”
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Influence of Methanol on Prion Reduction during High Temperature and High Pressure Oleochemical Processes by Mohammadi, Behnam, Raudner, Robert, Shafiq, Mohsin, Ahn, Edgar, Altmeppen, Hermann C., Glatzel, Markus

“…Prion‐reduction in standard biodiesel processes is caused by acidic and alkaline conditions. In the alternative RepCat biodiesel process, efficient…”
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Accelerating fingerprint identification using FPGA for large-scale applications by Shafiq, Mohsin, Taj, Imtiaz A., Ghafoor, Mubeen, Tariq, Syed Ali, Abbas, Assad, Zomaya, Albert Y.

“…Fingerprint-based human authentication has shown great potential for civil, forensic and corporate security applications in recent years. For large-scale…”
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OS-027-YI Immune checkpoint profiles on circulating extracellular vesicles predict response to immunotherapy in heptaocellular carcinoma by Masood, Ramsha, Buescher, Gustav, Gorgulho, Joao, Giehren, Franziska, Pagani, Francesca, Kocheise, Lorenz, Jörg, Vincent, Schmidt, Constantin, Adlung, Lorenz, Waldmann, Moritz, Renne, Thomas, Krause, Jenny, Sauter, Guido, Ricklefs, Franz, Maire, Cecile, Shafiq, Mohsin, Lohse, Ansgar W., Huber, Samuel, Wege, Henning, Zimpel, Carolin, Marquardt, Jens U., Scheiner, Bernhard, Balcar, Lorenz, Pinter, Matthias, de Toni, Enrico, Piseddu, Ignazio, Khaled, Najib Ben, Schulze, Kornelius, von Felden, Johann

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