Search Results - "Shafiei, Vahid"

CRISPR/Cas9 technology as a potent molecular tool for gene therapy by Karimian, Ansar, Azizian, Khalil, Parsian, Hadi, Rafieian, Sona, Shafiei‐Irannejad, Vahid, Kheyrollah, Maryam, Yousefi, Mehdi, Majidinia, Maryam, Yousefi, Bahman

“…Clustered regularly interspaced short palindromic repeats/CRISPR‐associated nuclease 9 (CRISPR‐Cas9) is an RNA‐guided gene editing tool which offers several…”
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Synthesis of Magnetic Nanocarrier Conjugated by Folate Based on Tragacanth and In Vitro Investigation of their Efficiency on Breast Cancer Cells by Jalali, Somayeh, Moghadam, Peyman Najafi, Shafiei‐Irannejad, Vahid

“…In this research, a novel nanocarrier is synthesized based on tragacanth as a natural polysaccharide. For this purpose, carboxymethyl tragacanth (CMT) is first…”
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New potentials for 3‐hydroxy‐3‐methyl‐glutaryl‐coenzymeA reductase inhibitors: Possible applications in retarding diabetic complications by Bahrambeigi, Saman, Rahimi, Mahdi, Yousefi, Bahman, Shafiei‐Irannejad, Vahid

“…The prevalence of diabetes mellitus is increasing all over the world and it is apparent that treatment of diabetic complications has the same importance as…”
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Remote consultations in primary care: Patient experiences and suggestions for improvement by de Visser, Richard O, Nwamba, Chimela, Brearley, Eve, Shafiei, Vahid, Hart, Lia

“…The use of Remote Consultations (RCs) in primary care expanded rapidly during the Covid-19 pandemic: their ongoing use highlights a need to improve experiences…”
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Redox and pH‐Responsive NCC/L‐Cysteine/CM‐β‐CD/FA Contains Disulfide Bond‐Bridged as Nanocarriers for Biosafety and Anti‐Tumor Efficacy System by Ehsanimehr, Sedigheh, Moghadam, Peyman Najafi, Dehaen, Wim, Shafiei‐Irannejad, Vahid

“…In the present research, a new nanocarrier for targeted drug delivery to tumor cells based on nanocrystalline cellulose (NCC) was synthesized. For this…”
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Metformin; an old antidiabetic drug with new potentials in bone disorders by Bahrambeigi, Saman, Yousefi, Bahman, Rahimi, Mahdi, Shafiei-Irannejad, Vahid

“…[Display omitted] •AMPK pathway is the main distinguished mechanism of action for metformin.•AMPK induces osteogenesis and inhibits adipogenesis of bone marrow…”
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Balaglitazone reverses P-glycoprotein-mediated multidrug resistance via upregulation of PTEN in a PPARγ-dependent manner in leukemia cells by Yousefi, Bahman, Azimi, Ako, Majidinia, Maryam, Shafiei-Irannejad, Vahid, Badalzadeh, Reza, Baradaran, Behzad, Zarghami, Nosratollah, Samadi, Nasser

“…Multidrug resistance in tumor cells is still a big challenge in cancer treatment. Therefore, identification ofsafe and effective multidrug resistance–reversing…”
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Effects of Postbiotics from Food Probiotic and Protective Cultures on Proliferation and Apoptosis in HCT-116 Colorectal Cancer Cells by Behnam Omidi sarajar, Arash Alizadeh, Mehran Moradi, Vahid Shafiei Irannejad

“…Background and Objective: Postbiotics are microbial-derived soluble products, which are released during the growth and fermentation process of beneficial…”
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PEI grafted Fe3O4@SiO2@SBA-15 labeled FA as a pH-sensitive mesoporous magnetic and biocompatible nanocarrier for targeted delivery of doxorubicin to MCF-7 cell line by Ehsanimehr, Sedigheh, Moghadam, Peyman Najafi, Dehaen, Wim, Irannejad, Vahid Shafiei

“…[Display omitted] •The synthesized targeted MMNPs nanocarrier is biocompatible.•The DOX loaded targeted MMNPs nanocarrier showed a pH-dependent release…”
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Overexpression of tensin homolog deleted on chromosome ten (PTEN) by ciglitazone sensitizes doxorubicin‐resistance leukemia cancer cells to treatment by Mashayekhi, Samira, Yousefi, Bahman, Tohidi, Ehsan, Darband, Saber Ghazizadeh, Mirza‐Aghazadeh‐Attari, Mohammad, Sadighparvar, Shirin, Kaviani, Mojtaba, Shafiei‐Irannejad, Vahid, Kafil, Hossein Samadi, Karimian, Ansar, Jadidi‐Niaragh, Farhad, Majidinia, Maryam

“…Overcoming multidrug resistance (MDR) is a final goal of various recent studies, in which combination of different compounds and conventional chemotherapeutics…”
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Investigation of the Molecular Mechanism of Coagulopathy in Severe and Critical Patients With COVID-19 by Elieh Ali Komi, Daniel, Rahimi, Yaghoub, Asghari, Rahim, Jafari, Reza, Rasouli, Javad, Mohebalizadeh, Mehdi, Abbasi, Ata, Nejadrahim, Rahim, Rezazadeh, Farzin, Shafiei-Irannejad, Vahid

“…Coagulopathy is a frequently reported finding in the pathology of coronavirus disease 2019 (COVID-19); however, the molecular mechanism, the involved…”
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Metformin enhances doxorubicin sensitivity via inhibition of doxorubicin efflux in P‐gp‐overexpressing MCF‐7 cells by Shafiei‐Irannejad, Vahid, Samadi, Nasser, Yousefi, Bahman, Salehi, Roya, Velaei, Kobra, Zarghami, Nosratollah

“…Resistance against chemotherapy is still a major problem in successful cancer treatment in the clinic. Therefore, identifying new compounds with lower…”
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Sanguinarine enhances cisplatin sensitivity via glutathione depletion in cisplatin‐resistant ovarian cancer (A2780) cells by Sarkhosh‐Inanlou, Roya, Molaparast, Morteza, Mohammadzadeh, Adel, Shafiei‐Irannejad, Vahid

“…Ovarian cancer is considered as one of the most lethal gynecological cancers, and cisplatin‐based therapy has an important role as the first‐line option for…”
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New insights into antidiabetic drugs: Possible applications in cancer treatment by Shafiei‐Irannejad, Vahid, Samadi, Nasser, Salehi, Roya, Yousefi, Bahman, Zarghami, Nosratollah

“…Globally at 2014, it was estimated that there was 347 million people with diabetes in which 90 percent of them were diagnosed with type 2 diabetes mellitus…”
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Peroxisome Proliferator-Activated Receptor Ligands and Their Role in Chronic Myeloid Leukemia: Therapeutic Strategies by Yousefi, Bahman, Samadi, Nasser, Baradaran, Behzad, Shafiei-Irannejad, Vahid, Zarghami, Nosratollah

“…Imatinib therapy remains the gold standard for treatment of chronic myeloid leukemia; however, the acquired resistance to this therapeutic agent in patients…”
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Enhanced compressed sensing autofocus for high-resolution airborne synthetic aperture radar by Beheshti, Mojtaba, Shafiei, Vahid, Narimani, Hamed

“…The limited accuracy of the navigation system leads to deviations between the real and measured trajectories in airborne synthetic aperture radar (SAR) which…”
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Human umbilical cord mesenchymal stem cell-derived exosomes alleviate the severity of experimental autoimmune encephalomyelitis and enhance lag-3 expression on foxp3 + CD4 + T cells by Mohammadzadeh, Adel, Lahouty, Masoud, charkhian, Hamed, Ghafour, Arash Adamnejad, Moazzendizaji, Sahand, rezaei, Jafar, alipour, Shahriar, Irannejad, Vahid Shafiei, Ansari, Mohammad Hassan Khadem

“…Background Multiple sclerosis (MS) is a complex autoimmune disease that affects the central nervous system, causing inflammation, demyelination, and…”
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Immune-mediated anti-tumor effects of metformin; targeting metabolic reprogramming of T cells as a new possible mechanism for anti-cancer effects of metformin by Bahrambeigi, Saman, Shafiei-Irannejad, Vahid

“…[Display omitted] Immunotherapy-based cancer treatment has revolutionized the era of cancer patients recuperation and it has brought a strong hope to treatment…”
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Serum Arsenic and Lipid Peroxidation Levels in Patients with Multiple Sclerosis by Yousefi, Bahman, Ahmadi, Yasin, Ghorbanihaghjo, Amir, Faghfoori, Zeinab, irannejad, Vahid Shafiei

“…Oxidative stress plays a crucial role in the pathogenesis of multiple sclerosis (MS). Previous studies have shown that oxidative stress is one of the main…”
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Synthesis and characterization of novel hybrid nanomaterials based on β-cyclodextrine grafted halloysite nanotubes for delivery of doxorubicin to MCF-7 cell line by Shafiei-Irannejad, Vahid, Rahimkhoei, Vahid, Molaparast, Morteza, Akbari, Ali

“…•β-cyclodextrine grafted halloysite nanotubes were synthesized and characterized.•The obtained nanocarrier was applied to adsorption and release of…”
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