Search Results - "Shafiee-Ardestani Mehdi"

Pressure responsive nanogel base on Alginate‐Cyclodextrin with enhanced apoptosis mechanism for colon cancer delivery by Hosseinifar, Tolou, Sheybani, Simin, Abdouss, Majid, Hassani Najafabadi, Sayed Alireza, Shafiee Ardestani, Mehdi

“…5‐Fluorouracil (5‐Fu) commonly use in the treatment of different kinds of cancer, but limited cellular uptake and death is still a problem. Herein, we report a…”
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Sodium alginate/xanthan-based nanocomposite hydrogels containing 5-fluorouracil: Characterization and cancer cell death studies in presence of halloysite nanotube by Zolfagharian, Shadi, Zahedi, Payam, Shafiee Ardestani, Mehdi, Khatibi, Alireza, Jafarkhani, Saeed

“…[Display omitted] •Preparing sodium treated HNT (tHNT)/alginate/xanthan/5-FU nanocomposite hydrogels.•Improving thermal/mechanical properties of hydrogels by…”
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Pseudomonas aeruginosa PAO1 outer membrane vesicles-diphtheria toxoid conjugate as a vaccine candidate in a murine burn model by Zare Banadkoki, Ehsan, Rasooli, Iraj, Ghazanfari, Tooba, Siadat, Seyed Davar, Shafiee Ardestani, Mehdi, Owlia, Parviz

“…Pseudomonas aeruginosa is an opportunistic pathogen considered a common cause of nosocomial infection with high morbidity and mortality in burn patients…”
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Novel Nanosized Chitosan-Betulinic Acid Against Resistant Leishmania Major and First Clinical Observation of such parasite in Kidney by Zadeh Mehrizi, Tahereh, Shafiee Ardestani, Mehdi, Haji Molla Hoseini, Mostafa, Khamesipour, Ali, Mosaffa, Nariman, Ramezani, Amitis

“…Regarding the antiparasitic effects of Betulinic acid (B) against Leishmaniasis, it was loaded into nanochitosan (K) for the first time in order to improve its…”
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Exotoxin A-PLGA nanoconjugate vaccine against Pseudomonas aeruginosa infection: protectivity in murine model by Safari Zanjani, Leila, Shapouri, Reza, Dezfulian, Mehrouz, Mahdavi, Mehdi, Shafiee Ardestani, Mehdi

“…Pseudomonas aeruginosa is the major infectious agent of concern for cystic fibrosis (CF) patients. Therefore, it is necessary to develop appropriate strategies…”
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Conjugation of VEGFR1/R2-targeting peptide with gold nanoparticles to enhance antiangiogenic and antitumoral activity by Zanjanchi, Pegah, Asghari, S Mohsen, Mohabatkar, Hassan, Shourian, Mostafa, Shafiee Ardestani, Mehdi

“…Inhibition of tumor angiogenesis through simultaneous targeting of vascular endothelial growth factor receptor (VEGFR)-1 and -2 is highly efficacious. An…”
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CD133-Functionalized Gold Nanoparticles as a Carrier Platform for Telaglenastat (CB-839) against Tumor Stem Cells by Poonaki, Elham, Nickel, Ann-Christin, Shafiee Ardestani, Mehdi, Rademacher, Lars, Kaul, Marilyn, Apartsin, Evgeny, Meuth, Sven G, Gorji, Ali, Janiak, Christoph, Kahlert, Ulf Dietrich

“…The failure of a long-lasting curative therapeutic benefit of currently applied chemotherapies against malignant cancers is suggested to be caused by the…”
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Technetium-99m chelator-free radiolabeling of specific glutamine tumor imaging nanoprobe: in vitro and in vivo evaluations by Ghoreishi, Seyedeh Masoumeh, Khalaj, Ali, Sabzevari, Omid, Badrzadeh, Leila, Mohammadzadeh, Pardis, Mousavi Motlagh, Seyed Shahaboddin, Bitarafan-Rajabi, Ahmad, Shafiee Ardestani, Mehdi

“…Nowadays, molecular imaging radiopharmaceuticals', nanoparticles', and/or small-molecule biomarkers' applications are increasing rapidly worldwide. Thus,…”
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Mesoporous silica nanoparticles functionalized with folic acid/methionine for active targeted delivery of docetaxel by Khosravian, Pegah, Shafiee Ardestani, Mehdi, Khoobi, Mehdi, Ostad, Seyed Naser, Dorkoosh, Farid Abedin, Akbari Javar, Hamid, Amanlou, Massoud

“…Mesoporous silica nanoparticles (MSNs) are known as carriers with high loading capacity and large functionalizable surface area for target-directed delivery…”
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A Modified PEG-Fe3O4 Magnetic Nanoparticles Conjugated with D( +)Glucosamine (DG): MRI Contrast Agent by Rezayan, Ali Hossein, Kheirjou, Somayyeh, Edrisi, Maryam, Shafiee Ardestani, Mehdi, Alvandi, Hale

“…Molecular imaging (MI) can provide not only structural images utilizing temporal imaging techniques, but also functional and molecular data using a variety of…”
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Inherent anti-HIV activity of biocompatible anionic citrate-PEG-citrate dendrimer by Kandi, Mohammad Reza, Mohammadnejad, Javad, Shafiee Ardestani, Mehdi, Zabihollahi, Rezvan, Soleymani, Sepehr, Aghasadeghi, Mohammad Reza, Baesi, Kazem

“…The development of new combinations to empower better protection against HIV infection is particularly important. Anionic polymers can block HIV infection. In…”
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Gold nanoparticle conjugation and tumor accumulation of a VEGF receptor-targeting peptidomimetic by Navidi-Moghadam-Foumani, Reza, Fazilati, Mohammad, Shafiee Ardestani, Mehdi, Zanjanchi, Pegah, Asghari, S. Mohsen

“…Gold nanoparticles (GNPs) exhibit promising potential for both cancer treatment and diagnosis. While the conjugation with tumor-targeting peptides enhances…”
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Development of novel radiolabeled antibody-conjugated graphene quantum dots for targeted in vivo breast cancer imaging and biodistribution studies by Ganji Arjenaki, Raziyeh, Samieepour, Ghazaleh, Sadat Ebrahimi, Seyed Esmaeil, Pirali Hamedani, Morteza, Saffari, Mostafa, Seyedhamzeh, Mohammad, Kamali, Ali N., Najdian, Atena, Shafiee Ardestani, Mehdi

“…Nanotechnology-based drug delivery platforms have emerged as one of the promising approaches for the diagnosis and treatment of cancers. Furthermore,…”
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Prophylactic and Therapeutic Effects of MOG-Conjugated PLGA Nanoparticles in C57Bl/6 Mouse Model of Multiple Sclerosis by Gholamzad, Mehrdad, Baharlooi, Hussein, Shafiee Ardestani, Mehdi, Seyedkhan, Zeinab, Azimi, Maryam

“…Purpose: Multiple sclerosis (MS) is a debilitating neuroinflammatory disorder of the central nervous system. It is believed to result from an impaired immune…”
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Targeting BMI-1 with PLGA–PEG nanoparticle-containing PTC209 modulates the behavior of human glioblastoma stem cells and cancer cells by Poonaki, Elham, Ariakia, Fatemeh, Jalili-Nik, Mohammad, Shafiee Ardestani, Mehdi, Tondro, Gholamhossein, Samini, Fariborz, Ghasemi, Sepideh, Sahab-Negah, Sajad, Gorji, Ali

“…Despite advances in glioblastoma (GBM) treatments, current approaches have failed to improve the overall survival of patients. The oncogene BMI-1, a core…”
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Synthesis of novel nano-radiotracer for in-vivo bone imaging: 99mTc- citric acid based PEG dendrimer and its conjugation with alendronate by davoodikia, Behnam, Pirali Hamedani, Morteza, Saffari, Mostafa, Esmaeil Sadat Ebrahimi, Seyed, Seyyed hamzeh, Mohammad, Hashemi, Shaghayegh, Shafiee Ardestani, Mehdi, Masoumeh Ghoreishi, Seyedeh

“…Bone scan is the test that guide physician to diagnose diseases in the bone at the early stage, to prevent metastases to other organs. In this study, citric…”
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PEGylation of graphene/iron oxide nanocomposite: assessment of release of doxorubicin, magnetically targeted drug delivery and photothermal therapy by Ramezani Farani, Marzieh, Khadiv-Parsi, Parissa, Riazi, Gholam Hossein, Shafiee Ardestani, Mehdi, Saligheh Rad, Hamidreza

“…Scientists have recommended to investigate graphene and graphene base compounds for their potential uses in a variety of fields, such as biomedicine and drug…”
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Synthesis and labeling of p-NH2-Bn-DTPA-(Dabcyl-Lys6,Phe7)-pHBSP with 99mTc as a radiopeptide scintigraphic agent to detect cardiac ischemia by Mohtavinejad, Naser, Bitarafan-Rajabi, Ahmad, Shafiee Ardestani, Mehdi, Darbandi-Azar, Amir, Khalaj, Ali, Ghodrati, Atefe, Asadi, Mehdi, Amanlou, Massoud

“…Myocardial ischemia and infarction represent a major health burden worldwide, but their immediate diagnosis can reduce mortality and healthcare costs…”
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MALDI-MS: a Rapid and Reliable Method for Drug-to-Antibody Ratio Determination of Antibody-Drug Conjugates by Abedi, Mehri, Ahangari Cohan, Reza, Mahboudi, Fereidoun, Shafiee Ardestani, Mehdi, Davami, Fatemeh

“…It is believed that the loading value of anticancer drug conjugated to the monoclonal antibody, called drug-to-antibody ratio (DAR), is the main quality…”
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Production of an Antibody Fragment (scFv) Targeting PcrV Protein of Pseudomonas aeruginosa in Fed-Batch Cultivation Mode by Karam, Saba, Raigani, Mozhgan, Hassani Afshar, Sahar, Talebkhan, Yeganeh, Bayat, Elham, Komijani, Samira, Nematollahi, Leila, Barkhordari, Farzaneh, Shafiee Ardestani, Mehdi, Davami, Fatemeh

“…Pseudomonas aeruginosa is one of the opportunistic pathogens causing frequent hospital-acquired life-threatening infections in mechanically ventilated…”
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