Search Results - "Shafer, M."

Antimicrobial Resistance in Neisseria gonorrhoeae in the 21st Century: Past, Evolution, and Future by UNEMO, Magnus, SHAFER, William M

“…Neisseria gonorrhoeae is evolving into a superbug with resistance to previously and currently recommended antimicrobials for treatment of gonorrhea, which is a…”
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Antibiotic resistance in Neisseria gonorrhoeae: origin, evolution, and lessons learned for the future by Unemo, Magnus, Shafer, William M.

“…The strict human pathogen Neisseria gonorrhoeae has caused gonorrhea for thousands of years, and currently gonorrhea is the second most prevalent bacterial…”
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Drug discovery considerations in the development of covalent inhibitors by Mah, Robert, Thomas, Jason R, Shafer, Cynthia M

“…In recent years, the number of drug candidates with a covalent mechanism of action progressing through clinical trials or being approved by the FDA has…”
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Iron Solubility Related to Particle Sulfur Content in Source Emission and Ambient Fine Particles by Oakes, M, Ingall, E. D, Lai, B, Shafer, M. M, Hays, M. D, Liu, Z. G, Russell, A. G, Weber, R. J

“…The chemical factors influencing iron solubility (soluble iron/total iron) were investigated in source emission (e.g., biomass burning, coal fly ash, mineral…”
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Global Perspective on the Oxidative Potential of Airborne Particulate Matter: A Synthesis of Research Findings by Saffari, Arian, Daher, Nancy, Shafer, Martin M, Schauer, James J, Sioutas, Constantinos

“…An emerging hypothesis in the field of air pollution is that oxidative stress is one of the important pathways leading to adverse health effects of airborne…”
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Observation of a multimode plasma response and its relationship to density pumpout and edge-localized mode suppression by Paz-Soldan, C, Nazikian, R, Haskey, S R, Logan, N C, Strait, E J, Ferraro, N M, Hanson, J M, King, J D, Lanctot, M J, Moyer, R A, Okabayashi, M, Park, J-K, Shafer, M W, Tobias, B J

“…Density pumpout and edge-localized mode (ELM) suppression by applied n=2 magnetic fields in low-collisionality DIII-D plasmas are shown to be correlated with…”
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Single Exposure to near Roadway Particulate Matter Leads to Confined Inflammatory and Defense Responses: Possible Role of Metals by Pardo, Michal, Shafer, Martin M, Rudich, Assaf, Schauer, James J, Rudich, Yinon

“…Inhalation of traffic-associated atmospheric particulate matter (PM2.5) is recognized as a significant health risk. In this study, we focused on a single…”
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Clinical Factors Affecting the Accuracy of Guided Implant Surgery—A Systematic Review and Meta-analysis by Zhou, Wenjuan, Liu, Zhonghao, Song, Liansheng, Kuo, Chia-ling, Shafer, David M.

“…To systematically review the current dental literature regarding clinical accuracy of guided implant surgery and to analyze the involved clinical factors…”
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Pedestal bifurcation and resonant field penetration at the threshold of edge-localized mode suppression in the DIII-D Tokamak by Nazikian, R, Paz-Soldan, C, Callen, J D, deGrassie, J S, Eldon, D, Evans, T E, Ferraro, N M, Grierson, B A, Groebner, R J, Haskey, S R, Hegna, C C, King, J D, Logan, N C, McKee, G R, Moyer, R A, Okabayashi, M, Orlov, D M, Osborne, T H, Park, J-K, Rhodes, T L, Shafer, M W, Snyder, P B, Solomon, W M, Strait, E J, Wade, M R

“…Rapid bifurcations in the plasma response to slowly varying n=2 magnetic fields are observed as the plasma transitions into and out of edge-localized mode…”
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Genomic evolution of Neisseria gonorrhoeae since the preantibiotic era (1928-2013): antimicrobial use/misuse selects for resistance and drives evolution by Golparian, Daniel, Harris, Simon R, Sánchez-Busó, Leonor, Hoffmann, Steen, Shafer, William M, Bentley, Stephen D, Jensen, Jörgen S, Unemo, Magnus

“…Multidrug-resistant Neisseria gonorrhoeae strains are prevalent, threatening gonorrhoea treatment globally, and understanding of emergence, evolution, and…”
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Integration of full divertor detachment with improved core confinement for tokamak fusion plasmas by Wang, L., Wang, H. Q., Ding, S., Garofalo, A. M., Gong, X. Z., Eldon, D., Guo, H. Y., Leonard, A. W., Hyatt, A. W., Qian, J. P., Weisberg, D. B., McClenaghan, J., Fenstermacher, M. E., Lasnier, C. J., Watkins, J. G., Shafer, M. W., Xu, G. S., Huang, J., Ren, Q. L., Buttery, R. J., Humphreys, D. A., Thomas, D. M., Zhang, B., Liu, J. B.

“…Divertor detachment offers a promising solution to the challenge of plasma-wall interactions for steady-state operation of fusion reactors. Here, we…”
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Importance of Multidrug Efflux Pumps in the Antimicrobial Resistance Property of Clinical Multidrug-Resistant Isolates of Neisseria gonorrhoeae by GOLPARIAN, Daniel, SHAFER, William M, OHNISHI, Makoto, UNEMO, Magnus

“…The contribution of drug efflux pumps in clinical isolates of Neisseria gonorrhoeae that express extensively drug-resistant or multidrug-resistant phenotypes…”
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The serogroup B meningococcal outer membrane vesicle-based vaccine 4CMenB induces cross-species protection against Neisseria gonorrhoeae by Leduc, Isabelle, Connolly, Kristie L, Begum, Afrin, Underwood, Knashka, Darnell, Stephen, Shafer, William M, Balthazar, Jacqueline T, Macintyre, Andrew N, Sempowski, Gregory D, Duncan, Joseph A, Little, Marguerite B, Rahman, Nazia, Garges, Eric C, Jerse, Ann E

“…There is a pressing need for a gonorrhea vaccine due to the high disease burden associated with gonococcal infections globally and the rapid evolution of…”
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Seasonal variations in the oxidative stress and inflammatory potential of PM2.5 in Tehran using an alveolar macrophage model; The role of chemical composition and sources by Al Hanai, Ahlam H., Antkiewicz, Dagmara S., Hemming, Jocelyn D.C., Shafer, Martin M., Lai, Alexandra M., Arhami, Mohammad, Hosseini, Vahid, Schauer, James J.

“…The current study was designed to assess the association between temporal variations in urban PM2.5 chemical composition, sources, and the oxidative stress and…”
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Spatial and Temporal Control of Photomediated Disulfide–Ene and Thiol–Ene Chemistries for Two-Stage Polymerizations by Soars, Shafer M, Bongiardina, Nicholas J, Fairbanks, Benjamin D, Podgórski, Maciej, Bowman, Christopher N

“…A new strategy is reported for the design and synthesis of high sulfur-containing materials for potential use in covalent adaptable networks and optical…”
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Macrophage reactive oxygen species activity of water-soluble and water-insoluble fractions of ambient coarse, PM2.5 and ultrafine particulate matter (PM) in Los Angeles by Wang, Dongbin, Pakbin, Payam, Shafer, Martin M., Antkiewicz, Dagmara, Schauer, James J., Sioutas, Constantinos

“…This study describes an investigation of the relative contributions of water-soluble and water-insoluble portions of ambient particulate matter (PM) to…”
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Transcriptional responses of Neisseria gonorrhoeae to glucose and lactate: implications for resistance to oxidative damage and biofilm formation by Ayala, Julio C, Balthazar, Jacqueline T, Shafer, William M

“…Understanding how bacteria adapt to different environmental conditions is crucial for advancing knowledge regarding pathogenic mechanisms that operate during…”
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Multidrug-resistant gonorrhea: A research and development roadmap to discover new medicines by Alirol, Emilie, Wi, Teodora E, Bala, Manju, Bazzo, Maria Luiza, Chen, Xiang-Sheng, Deal, Carolyn, Dillon, Jo-Anne R, Kularatne, Ranmini, Heim, Jutta, Hooft van Huijsduijnen, Rob, Hook, Edward W, Lahra, Monica M, Lewis, David A, Ndowa, Francis, Shafer, William M, Tayler, Liz, Workowski, Kimberly, Unemo, Magnus, Balasegaram, Manica

“…Emilie Alirol and colleagues discuss the development of new treatments for gonorrhea…”
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Nighttime aqueous-phase secondary organic aerosols in Los Angeles and its implication for fine particulate matter composition and oxidative potential by Saffari, Arian, Hasheminassab, Sina, Shafer, Martin M., Schauer, James J., Chatila, Talal A., Sioutas, Constantinos

“…Recent investigations suggest that aqueous phase oxidation of hydrophilic organic compounds can be a significant source of secondary organic aerosols (SOA) in…”
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Redox activity of urban quasi-ultrafine particles from primary and secondary sources by Verma, Vishal, Ning, Zhi, Cho, Arthur K., Schauer, James J., Shafer, Martin M., Sioutas, Constantinos

“…To characterize the redox activity profiles of atmospheric aerosols from primary (traffic) and secondary photochemical sources, ambient quasi-ultrafine…”
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