Search Results - "Shadiow, James"
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Loss of NAMPT and SIRT2 but not SIRT1 attenuate GLO1 expression and activity in human skeletal muscle
Published in Redox biology (01-09-2024)“…Glyoxalase I (GLO1) is the primary enzyme for detoxification of the reactive dicarbonyl methylglyoxal (MG). Loss of GLO1 promotes accumulation of MG resulting…”
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The acute effects of vinyasa flow yoga on vascular function, lipid and glucose concentrations, and mood
Published in Complementary therapies in medicine (01-01-2021)“…•This study documents novel information regarding the acute vascular effects of yoga.•Our results highlight the efficacy of vinyasa yoga in reducing…”
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Abstract P196: Hot Yoga and Hypertension: Exploration of a Novel Lifestyle Intervention
Published in Hypertension (Dallas, Tex. 1979) (01-09-2019)“…Abstract only The practice of hot yoga is becoming widespread as marked by a growing number of yoga studios offering classes in heated rooms ranging in…”
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Characterization and Strategies for Resolution of Aberrant Endothelial Function in Patients With Type 2 Diabetes: Implications for Wound Healing
Published 01-01-2023“…Endothelial cell (EC) dysfunction plays a major role in the pathogenesis of diabetic foot ulcers (DFUs) due to limitations on nutritive and oxygenated blood…”
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Abstract 1101: Tnfa-setdb2 Pathway Regulates Fibroblast To Myofibroblast Transition In Wound Repair
Published in Arteriosclerosis, thrombosis, and vascular biology (01-05-2024)“…Abstract only Effective healing following tissue injury is predicated on an intimate coordination between immune cells and structural cells, where recruited…”
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TGFb-JMJD3 pathway regulates fibroblast to myofibroblast transition in wound repair
Published in The Journal of immunology (1950) (01-05-2024)“…Abstract In normal wound healing, resident fibroblasts transition to myofibroblasts, which function to contract and close wounds. In pathologic conditions…”
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Abstract 2140: The Tgfb-Whsc1 Axis Drives Macrophage To Myofibroblast Transition During Wound Repair
Published in Arteriosclerosis, thrombosis, and vascular biology (01-05-2024)“…Abstract only During the proliferative phase of tissue repair macrophages can transition to myofibroblasts, which promote wound contraction and closure. The…”
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Abstract 2141: An IL12/IL23 Positive Feedback Loop Modulates Smooth Muscle Differentiation Via Setd4 During Macrophage-mediated Inflammation
Published in Arteriosclerosis, thrombosis, and vascular biology (01-05-2024)“…Abstract only Diabetic patients have increased risk of vascular disease (e.g., atherosclerosis), which is driven by macrophage-mediated inflammation. In…”
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IL-17A-mediated JMJD3 regulation of Cxcl1 gene expression in diabetic keratinocytes increases neutrophil recruitment and impairs wound repair
Published in The Journal of immunology (1950) (01-05-2024)“…Abstract Diabetic keratinocytes display an overexpression of chemokines that contribute to prolonged inflammation and non-healing. Using sequencing, we…”
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Acute Effects of a Vinyasa Flow Yoga DVD on Lipid Profile and Fasting Glucose: 975 Board #209 May 29 2:00 PM - 3:30 PM
Published in Medicine and science in sports and exercise (01-06-2019)Get full text
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The Acute Effects of Vinyasa Flow Yoga on Arterial Stiffness: 977 Board #211 May 29 2:00 PM - 3:30 PM
Published in Medicine and science in sports and exercise (01-06-2019)Get full text
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Macrophage-specific inhibition of the histone demethylase JMJD3 decreases STING and pathologic inflammation in diabetic wound repair
Published in Cellular & molecular immunology (01-11-2022)“…Macrophage plasticity is critical for normal tissue repair following injury. In pathologic states such as diabetes, macrophage plasticity is impaired, and…”
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Exercise-induced changes to the fiber type-specific redox state in human skeletal muscle are associated with aerobic capacity
Published in Journal of applied physiology (1985) (01-09-2023)“…The benefits of exercise involve skeletal muscle redox state alterations of nicotinamide adenine dinucleotide (NAD) and flavin adenine dinucleotide (FAD). We…”
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243-LB: Enzymes for Dicarbonyl Detoxification Are Attenuated with Obesity by Mechanisms of Acetylation
Published in Diabetes (New York, N.Y.) (01-06-2020)“…Glyoxalase I (GLOI) is the primary enzyme for detoxifying the reactive dicarbonyl methylglyoxal. Pre-clinical models demonstrate that loss of GLOI promotes the…”
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Tnfa-setdb2 Pathway Regulates Fibroblast to Myofibroblast Transition in Wound Repair
Published in JVS-vascular science (01-10-2024)Get full text
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On diabetic foot ulcer knowledge gaps, innovation, evaluation, prediction markers, and clinical needs
Published in Journal of diabetes and its complications (01-11-2022)“…Diabetic foot ulcers (DFUs) remain a very prevalent and challenging complication of diabetes worldwide due to high morbidity, high risks of lower extremity…”
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The Tgfb-Whsc1 Axis Drives Macrophage to Myofibroblast Transition During Wound Repair
Published in JVS-vascular science (01-10-2024)Get full text
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Pharmacological modulation of vascular ageing: A review from VascAgeNet
Published in Ageing research reviews (01-12-2023)“…Vascular ageing, characterized by structural and functional changes in blood vessels of which arterial stiffness and endothelial dysfunction are key…”
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High Intensity Acute Aerobic Exercise Elicits Alterations in Circulating and Skeletal Muscle Tissue Expression of Neuroprotective Exerkines
Published in Brain plasticity (Amsterdam, Netherlands) (21-10-2022)“…Cathepsin B (CTSB) and brain derived neurotrophic factor (BDNF) are increased with aerobic exercise (AE) and skeletal muscle has been identified as a potential…”
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