Search Results - "Shadab Raza, Syed"
-
1
Inducing Angiogenesis, a Key Step in Cancer Vascularization, and Treatment Approaches
Published in Cancers (06-05-2020)“…Angiogenesis is a term that describes the formation of new blood and lymphatic vessels from a pre-existing vasculature. This allows tumour cells to acquire…”
Get full text
Journal Article -
2
Reactive oxygen species (ROS) in cancer pathogenesis and therapy: An update on the role of ROS in anticancer action of benzophenanthridine alkaloids
Published in Biomedicine & pharmacotherapy (01-11-2021)“…Reactive oxygen species play crucial role in biological homeostasis and pathogenesis of human diseases including cancer. In this line, now it has become…”
Get full text
Journal Article -
3
Biomaterial-based combinatorial approach of aescin-comprised zein-coated gelatin nanoparticles alleviates synovial inflammation in experimental inflammatory arthritis
Published in Nanoscale (25-04-2024)“…Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease that mostly affects joints. Although RA therapy has made significant progress,…”
Get more information
Journal Article -
4
MCC950 reduces autophagy and improves cognitive function by inhibiting NLRP3-dependent neuroinflammation in a rat model of Alzheimer's disease
Published in Brain, behavior, and immunity (01-02-2024)“…[Display omitted] •MCC950, an NLRP3 inhibitor, shows promise as a treatment for Alzheimer's disease (AD) by reversing Aβ plaque formation and improving…”
Get full text
Journal Article -
5
Nanoparticles mediated localized therapy abrogates autophagy through modulation of Beclin1 and Atg7 for the management of ischemia-reperfusion disorder
Published in Chemical engineering journal (Lausanne, Switzerland : 1996) (15-06-2022)“…[Display omitted] •3-MA-loaded NLCs were prepared using natural and FDA-approved materials under the GRAS category.•Various techniques were used to…”
Get full text
Journal Article -
6
Role of non-coding RNA networks in leukemia progression, metastasis and drug resistance
Published in Molecular cancer (12-03-2020)“…Early-stage detection of leukemia is a critical determinant for successful treatment of the disease and can increase the survival rate of leukemia patients…”
Get full text
Journal Article -
7
Resveratrol attenuates 6-hydroxydopamine-induced oxidative damage and dopamine depletion in rat model of Parkinson's disease
Published in Brain research (30-04-2010)“…Abstract The present study was undertaken to investigate the neuroprotective effects of resveratrol (RES) on 6-hydroxydopamine (6-OHDA)-induced Parkinson's…”
Get full text
Journal Article -
8
Sanguinarine mediated apoptosis in Non-Small Cell Lung Cancer via generation of reactive oxygen species and suppression of JAK/STAT pathway
Published in Biomedicine & pharmacotherapy (01-12-2021)“…Effective treatment of lung cancer remains a significant clinical challenge due to its multidrug resistance and side effects of the current treatment options…”
Get full text
Journal Article -
9
Pristimerin mediated anticancer effects and sensitization of human skin cancer cells through modulation of MAPK signaling pathways
Published in Biomedicine & pharmacotherapy (01-12-2022)“…Squamous cell carcinoma is a frequent skin cancer still demanding to understand the underlying mechanisms for better clinical outcomes. Pristimerin, a natural…”
Get full text
Journal Article -
10
Editorial: Advances in the imaging techniques of radiologically subtle CNS disorders
Published in Frontiers in neuroscience (03-11-2022)Get full text
Journal Article -
11
Cytokine-Mediated Dysregulation of Signaling Pathways in the Pathogenesis of Multiple Myeloma
Published in International journal of molecular sciences (15-07-2020)“…Multiple myeloma (MM) is a hematologic disorder of B lymphocytes characterized by the accumulation of malignant plasma cells (PCs) in the bone marrow. The…”
Get full text
Journal Article -
12
Comparative acute intravenous toxicity study of triple polymer-layered magnetic nanoparticles with bare magnetic nanoparticles in Swiss albino mice
Published in Nanotoxicology (01-12-2020)“…Iron-oxide nanoparticles are one of the most commercialized nanomaterials and have gained widespread acceptance in nanotherapeutics due to their ability for…”
Get full text
Journal Article -
13
Thiol-Functionalized Cellulose-Grafted Copper Oxide Nanoparticles for the Therapy of Experimental Colitis in Swiss Albino Mice
Published in ACS biomaterials science & engineering (09-05-2022)“…Ulcerative colitis (UC) is a chronic inflammatory disease, which deleteriously affects the lower end of the gastrointestinal tract, i.e., the colon and the…”
Get full text
Journal Article -
14
Hesperidin ameliorates functional and histological outcome and reduces neuroinflammation in experimental stroke
Published in Brain research (28-10-2011)“…Abstract Incidence of stroke is considered to be a major cause of death throughout the world. The middle cerebral artery occlusion (MCAO) for 2 h followed by…”
Get full text
Journal Article -
15
Editorial: Advances and challenges in stroke therapy: A regenerative prospective
Published in Frontiers in neuroscience (12-12-2022)Get full text
Journal Article -
16
Rutin Protects Dopaminergic Neurons from Oxidative Stress in an Animal Model of Parkinson’s Disease
Published in Neurotoxicity research (01-07-2012)“…This study was undertaken to investigate the neuroprotective effects of rutin (vitamin P) on 6-hydroxydopamine (6-OHDA)-induced Parkinson’s disease (PD) in…”
Get full text
Journal Article -
17
Experimental Rodent Models of Vascular Dementia: A Systematic Review
Published in CNS & neurological disorders drug targets (01-01-2021)“…Vascular Dementia (VaD) occurs due to cerebrovascular insufficiency, which leads to decreased blood circulation to the brain, thereby resulting in mental…”
Get more information
Journal Article -
18
Silymarin protects neurons from oxidative stress associated damages in focal cerebral ischemia: A behavioral, biochemical and immunohistological study in Wistar rats
Published in Journal of the neurological sciences (15-10-2011)“…Abstract Cerebral stroke is the third largest cause of death and the severe leading cause of disability, thus have astronomical financial and social burden…”
Get full text
Journal Article -
19
Rutin protects the neural damage induced by transient focal ischemia in rats
Published in Brain research (25-09-2009)“…Abstract Free radical induced neural damage is implicated in cerebral ischemia–reperfusion (IR) injury and antioxidants are reported to have neuroprotective…”
Get full text
Journal Article -
20
Quercetin Protects Against Oxidative Stress Associated Damages in a Rat Model of Transient Focal Cerebral Ischemia and Reperfusion
Published in Neurochemical research (01-08-2011)“…Experimental studies have demonstrated that oxidative stress and apoptosis play an important role in cerebral ischemic pathogenesis and may represent a target…”
Get full text
Journal Article