Search Results - "Shackleford, Ghjuvan'Ghjacumu"
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Neuregulin 1 type III improves peripheral nerve myelination in a mouse model of congenital hypomyelinating neuropathy
Published in Human molecular genetics (15-04-2019)“…Abstract Myelin sheath thickness is precisely regulated and essential for rapid propagation of action potentials along myelinated axons. In the peripheral…”
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Lithium enhances remyelination of peripheral nerves
Published in Proceedings of the National Academy of Sciences - PNAS (06-03-2012)“…Glycogen synthase kinase 3β (GSK3β) inhibitors, especially the mood stabilizer lithium chloride, are also used as neuroprotective or anti-inflammatory agents…”
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Corrigendum: Neuregulin 1 type III improves peripheral nerve myelination in a mouse model of congenital hypomyelinating neuropathy
Published in Human molecular genetics (01-07-2019)Get full text
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Corrigendum: Neuregulin 1 type III improves peripheral nerve myelination in a mouse model of congenital hypomyelinating neuropathy
Published in Human molecular genetics (15-05-2019)Get full text
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The Activation of the WNT Signaling Pathway Is a Hallmark in Neurofibromatosis Type 1 Tumorigenesis
Published in Clinical cancer research (15-01-2014)“…The hallmark of neurofibromatosis type 1 (NF1) is the onset of dermal or plexiform neurofibromas, mainly composed of Schwann cells. Plexiform neurofibromas can…”
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A new mouse model of Charcot-Marie-Tooth 2J neuropathy replicates human axonopathy and suggest alteration in axo-glia communication
Published in PLoS genetics (09-11-2022)“…Myelin is essential for rapid nerve impulse propagation and axon protection. Accordingly, defects in myelination or myelin maintenance lead to secondary axonal…”
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Liver X receptors alpha and beta promote myelination and remyelination in the cerebellum
Published in Proceedings of the National Academy of Sciences - PNAS (16-06-2015)“…The identification of new pathways governing myelination provides innovative avenues for remyelination. Liver X receptors (LXRs) α and β are nuclear receptors…”
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Differential regulation of Wnt/beta-catenin signaling by Liver X Receptors in Schwann cells and oligodendrocytes
Published in Biochemical pharmacology (01-07-2013)“…Oxysterols are reactive molecules generated by the oxidation of cholesterol. Their implication in cholesterol homeostasis and in the progression of…”
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Involvement of Aryl hydrocarbon receptor in myelination and in human nerve sheath tumorigenesis
Published in Proceedings of the National Academy of Sciences - PNAS (06-02-2018)“…Aryl hydrocarbon receptor (AHR) is a ligand-activated transcription factor involved in xenobiotic metabolism. Plexiform neurofibromas (PNFs) can transform into…”
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Wnt and lithium: a common destiny in the therapy of nervous system pathologies?
Published in Cellular and molecular life sciences : CMLS (01-04-2014)“…Wnt signaling is required for neurogenesis, the fate of neural progenitors, the formation of neuronal circuits during development, neuron positioning and…”
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Interplay between LXR and Wnt/β-catenin signaling in the negative regulation of peripheral myelin genes by oxysterols
Published in The Journal of neuroscience (29-06-2011)“…Oxysterols are reactive molecules generated from the oxidation of cholesterol. Their implication in cholesterol homeostasis and in the progression of…”
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Liver X receptors alpha and beta promote myelination and remyelination in the cerebellum
Published in Proceedings of the National Academy of Sciences - PNAS (28-05-2015)“…Significance Liver X receptors (LXRs) α and β are the two major receptors of oxysterols, oxygenated derivatives of cholesterol. They control the homeostasis of…”
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