Search Results - "Shabir, Saqib"

Functional expression of purinergic P2 receptors and transient receptor potential channels by the human urothelium by Shabir, Saqib, Cross, William, Kirkwood, Lisa A, Pearson, Joanna F, Appleby, Peter A, Walker, Dawn, Eardley, Ian, Southgate, Jennifer

“…In addition to its role as a physical barrier, the urothelium is considered to play an active role in mechanosensation. A key mechanism is the release of…”
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Ketamine-Induced Apoptosis in Normal Human Urothelial Cells by Baker, Simon C, Shabir, Saqib, Georgopoulos, Nikolaos T, Southgate, Jennifer

“…Recreational abuse of ketamine has been associated with the emergence of a new bladder pain syndrome, ketamine-induced cystitis, characterized by chronic…”
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Differentiation-associated reprogramming of the transforming growth factor β receptor pathway establishes the circuitry for epithelial autocrine/paracrine repair by Fleming, Jonathan M, Shabir, Saqib, Varley, Claire L, Kirkwood, Lisa A, White, Angela, Holder, Julie, Trejdosiewicz, Ludwik K, Southgate, Jennifer

“…Transforming growth factor (TGF) β has diverse and sometimes paradoxical effects on cell proliferation and differentiation, presumably reflecting a fundamental…”
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Ketamine-Induced Apoptosis in Normal Human Urothelial Cells: A Direct, N-Methyl-d-Aspartate Receptor-Independent Pathway Characterized by Mitochondrial Stress by Baker, Simon C, Shabir, Saqib, Georgopoulos, Nikolaos T, Southgate, Jennifer

“…Recreational abuse of ketamine has been associated with the emergence of a new bladder pain syndrome, ketamine-induced cystitis, characterized by chronic…”
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Ketamine-Induced Apoptosis in Normal Human Urothelial Cells: A Direct, N-Methyl by Baker, Simon C., Shabir, Saqib, Georgopoulos, Nikolaos T., Southgate, Jennifer

“…Recreational abuse of ketamine has been associated with the emergence of a new bladder pain syndrome, ketamine-induced cystitis, characterized by chronic…”
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Biomimetic Urothelial Tissue Models for the in Vitro Evaluation of Barrier Physiology and Bladder Drug Efficacy by Baker, Simon C, Shabir, Saqib, Southgate, Jennifer

“…The bladder is an important tissue in which to evaluate xenobiotic drug interactions and toxicities due to the concentration of parent drug and…”
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Calcium signalling in wound-responsive normal human urothelial cell monolayers by Shabir, Saqib, Southgate, Jennifer

“…Summary Epithelial tissue repair requires coordination of migratory and proliferative activity both adjacent to and remote from the wound edge. Although…”
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Characterization and classification of adherent cells in monolayer culture using automated tracking and evolutionary algorithms by Zhang, Zhen, Bedder, Matthew, Smith, Stephen L., Walker, Dawn, Shabir, Saqib, Southgate, Jennifer

“…This paper presents a novel method for tracking and characterizing adherent cells in monolayer culture. A system of cell tracking employing computer vision…”
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Sources of variability in cytosolic calcium transients triggered by stimulation of homogeneous uro-epithelial cell monolayers by Appleby, Peter A., Shabir, Saqib, Southgate, Jennifer, Walker, Dawn

“…Epithelial tissue structure is the emergent outcome of the interactions between large numbers of individual cells. Experimental cell biology offers an…”
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Cell-type-specific modelling of intracellular calcium signalling: a urothelial cell model by Appleby, Peter A., Shabir, Saqib, Southgate, Jennifer, Walker, Dawn

“…Calcium signalling plays a central role in regulating a wide variety of cell processes. A number of calcium signalling models exist in the literature that are…”
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Differentiation-Associated Reprogramming of the Transforming Growth Factor [beta] Receptor Pathway Establishes the Circuitry for Epithelial Autocrine/Paracrine Repair by Fleming, Jonathan M, Shabir, Saqib, Varley, Claire L, Kirkwood, Lisa A, White, Angela, Holder, Julie, Trejdosiewicz, Ludwik K, Southgate, Jennifer

“…Transforming growth factor (TGF) [beta] has diverse and sometimes paradoxical effects on cell proliferation and differentiation, presumably reflecting a…”
Get full text