Search Results - "Shabestary, Kiyan"

Pooled CRISPRi screening of the cyanobacterium Synechocystis sp PCC 6803 for enhanced industrial phenotypes by Yao, Lun, Shabestary, Kiyan, Björk, Sara M., Asplund-Samuelsson, Johannes, Joensson, Haakan N., Jahn, Michael, Hudson, Elton P.

“…Cyanobacteria are model organisms for photosynthesis and are attractive for biotechnology applications. To aid investigation of genotype-phenotype…”
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Phenotypic heterogeneity follows a growth-viability tradeoff in response to amino acid identity by Shabestary, Kiyan, Klemm, Cinzia, Carling, Benedict, Marshall, James, Savigny, Juline, Storch, Marko, Ledesma-Amaro, Rodrigo

“…In their natural environments, microorganisms mainly operate at suboptimal growth conditions with fluctuations in nutrient abundance. The resulting cellular…”
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Computational metabolic engineering strategies for growth-coupled biofuel production by Synechocystis by Shabestary, Kiyan, Hudson, Elton P.

“…Chemical and fuel production by photosynthetic cyanobacteria is a promising technology but to date has not reached competitive rates and titers. Genome-scale…”
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Genetic and nutrient modulation of acetyl-CoA levels in Synechocystis for n-butanol production by Anfelt, Josefine, Kaczmarzyk, Danuta, Shabestary, Kiyan, Renberg, Björn, Rockberg, Johan, Nielsen, Jens, Uhlén, Mathias, Hudson, Elton P

“…There is a strong interest in using photosynthetic cyanobacteria as production hosts for biofuels and chemicals. Recent work has shown the benefit of pathway…”
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Systematic overexpression study to find target enzymes enhancing production of terpenes in Synechocystis PCC 6803, using isoprene as a model compound by Englund, Elias, Shabestary, Kiyan, Hudson, Elton P., Lindberg, Pia

“…Of the two natural metabolic pathways for making terpenoids, biotechnological utilization of the mevalonate (MVA) pathway has enabled commercial production of…”
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CRISPR interference screens reveal growth–robustness tradeoffs in Synechocystis sp. PCC 6803 across growth conditions by Miao, Rui, Jahn, Michael, Shabestary, Kiyan, Peltier, Gilles, Hudson, Elton P

“…Abstract Barcoded mutant libraries are a powerful tool for elucidating gene function in microbes, particularly when screened in multiple growth conditions…”
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Environmental impacts and limitations of third‐generation biobutanol: Life cycle assessment of n‐butanol produced by genetically engineered cyanobacteria by Nilsson, Astrid, Shabestary, Kiyan, Brandão, Miguel, Hudson, Elton P.

“…Photosynthetic cyanobacteria have attracted interest as production organisms for third‐generation biofuels, where sunlight and CO2 are used by microbes…”
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Targeted Repression of Essential Genes To Arrest Growth and Increase Carbon Partitioning and Biofuel Titers in Cyanobacteria by Shabestary, Kiyan, Anfelt, Josefine, Ljungqvist, Emil, Jahn, Michael, Yao, Lun, Hudson, Elton P

“…Photoautotrophic production of fuels and chemicals by cyanobacteria typically gives lower volumetric productivities and titers than heterotrophic production…”
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Cycling between growth and production phases increases cyanobacteria bioproduction of lactate by Shabestary, Kiyan, Hernández, Hugo Pineda, Miao, Rui, Ljungqvist, Emil, Hallman, Olivia, Sporre, Emil, Branco dos Santos, Filipe, Hudson, Elton P.

“…Decoupling growth from product synthesis is a promising strategy to increase carbon partitioning and maximize productivity in cell factories. However,…”
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Understanding resource competition to achieve predictable synthetic gene expression in eukaryotes by Di Blasi, Roberto, Gabrielli, Jacopo, Shabestary, Kiyan, Ziarti, Ioanna, Ellis, Tom, Kontoravdi, Cleo, Ledesma-Amaro, Rodrigo, Ceroni, Francesca

“…Synthetic gene expression in engineered cells typically depends on the host cell’s limited pool of intracellular resources, which can lead to resource…”
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