Search Results - "Shaban, Lamyaa"
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SKAP2 is required for defense against K. pneumoniae infection and neutrophil respiratory burst
Published in eLife (30-04-2020)“…is a respiratory, blood, liver, and bladder pathogen of significant clinical concern. We show that the adaptor protein, SKAP2, is required for protection…”
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Yersinia pseudotuberculosis YopH targets SKAP2-dependent and independent signaling pathways to block neutrophil antimicrobial mechanisms during infection
Published in PLoS pathogens (11-05-2020)“…Yersinia suppress neutrophil responses by using a type 3 secretion system (T3SS) to inject 6-7 Yersinia effector proteins (Yops) effectors into their…”
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Promises and Challenges of the Type Three Secretion System Injectisome as an Antivirulence Target
Published in Ecosal plus (01-02-2019)“…Antibiotic resistance is a major public health threat that has stimulated the scientific community to search for nontraditional therapeutic targets. Because…”
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The effect of diabetes on surgical versus percutaneous left main revascularization outcomes: a systematic review and meta-analysis
Published in Journal of cardiothoracic surgery (01-04-2022)“…The optimal method of coronary revascularization for diabetes mellitus (DM) patients with left main coronary artery disease (LMCAD) is controversial in the…”
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Prevalence and antimicrobial resistance pattern of bacterial meningitis in Egypt
Published in Annals of clinical microbiology and antimicrobials (24-09-2009)“…Infectious diseases are the leading cause of morbidity and mortality in the developing world. In Egypt bacterial diseases constitute a great burden, with…”
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Pre-colonization with the commensal fungus Candida albicans reduces murine susceptibility to Clostridium difficile infection
Published in Gut microbes (02-11-2018)“…Clostridium difficile is a major nosocomial pathogen responsible for close to half a million infections and 27,000 deaths annually in the U.S. Preceding…”
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Abstract 9448: The Effect of Diabetes on Cardiovascular Events After Coronary Artery Bypass Grafting versus Drug-Eluting Stents for Left Main Coronary Artery Disease: A Meta-Analysis
Published in Circulation (New York, N.Y.) (16-11-2021)“…BackgroundThe optimal method of coronary revascularization for diabetes mellitus (DM) patients with left main coronary artery disease (LMCAD) is controversial…”
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Yersinia YopH Targets SKAP2-dependent and Independent Signaling Pathways to Block Neutrophil Antimicrobial Mechanisms
Published 01-01-2019“…Yersinia elicits a pronounced inflammatory response in infected tissues where bacterial microcolonies are seen directly interfacing with neutrophils. Normally…”
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Dissertation -
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A 3D intestinal tissue model supports Clostridioides difficile germination, colonization, toxin production and epithelial damage
Published in Anaerobe (01-04-2018)“…Endospore-forming Clostridioides difficile is a causative agent of antibiotic-induced diarrhea, a major nosocomial infection. Studies of its interactions with…”
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Outbreak investigation: molecular characterization of Vibrio cholerae isolates from Horn of Africa
Published in BMC proceedings (01-07-2009)Get full text
Journal Article