Search Results - "Shabaan, Sara N."
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Synthesis of pyrido-annelated [1,2,4,5]tetrazines, [1,2,4]triazepine, and [1,2,4,5]tetrazepines for anticancer, DFT, and molecular docking studies
Published in Scientific reports (05-04-2023)“…In this strategy, we attempt to design various novel nitrogen-rich heterocycles in one molecule. Green, simple, and efficient aza-annulations of an active,…”
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New Pyrazole/Pyrimidine-Based Scaffolds as Inhibitors of Heat Shock Protein 90 Endowed with Apoptotic Anti-Breast Cancer Activity
Published in Pharmaceuticals (Basel, Switzerland) (27-09-2024)“…: Supported by a comparative study between conventional, grinding, and microwave techniques, a mild and versatile method based on the [1 + 3] cycloaddition of…”
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Ultrasound-assisted green synthesis and antimicrobial assessment of 1,3-thiazoles and 1,3,4-thiadiazines
Published in Green chemistry letters and reviews (02-10-2021)“…In this article, we applied ultrasonic irradiation as an ecofriendly, green, efficient approach for the synthesis of a new 1,3-thiazoles and 1,3,4-thiadiazines…”
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Synthesis and cytotoxic activity of some novel benzocoumarin derivatives under solvent free conditions
Published in Green chemistry letters and reviews (02-01-2019)“…In the present study, a rapid, less expensive, clean and environmental friendly route to synthesis new pyrazoles, pyrazolopyridazines and condensed pyrimidines…”
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DNA binding studies of novel diazatruxenones analogs as potential anticancer agents: Synthesis, antitumor investigation, DNA binding, SAR and molecular modeling calculation
Published in Bioorganic chemistry (01-11-2020)“…[Display omitted] •A series of polycyclic skeleton of truxene and triazatruxene analogs has been synthesized.•The synthesized candidates have been evaluated…”
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