Search Results - "Shaba, Enxhi"
-
1
Proteomics Reveals How the Tardigrade Damage Suppressor Protein Teaches Transfected Human Cells to Survive UV-C Stress
Published in International journal of molecular sciences (14-07-2023)“…The genome sequencing of the tardigrade revealed a unique nucleosome-binding protein named damage suppressor (Dsup), which was discovered to be crucial for the…”
Get full text
Journal Article -
2
Idiopathic Pulmonary Fibrosis Serum proteomic analysis before and after nintedanib therapy
Published in Scientific reports (10-06-2020)“…Idiopathic pulmonary fibrosis (IPF) is a fatal progressive disease with a median survival of 2–5 years. Nintedanib is a small tyrosine kinase inhibitor that…”
Get full text
Journal Article -
3
Neurodegenerative Disorder Risk in Krabbe Disease Carriers
Published in International journal of molecular sciences (04-11-2022)“…Krabbe disease (KD) is a rare autosomal recessive disorder caused by mutations in the galactocerebrosidase gene ( ). Defective GALC causes aberrant metabolism…”
Get full text
Journal Article -
4
Proteome Characterization of BALF Extracellular Vesicles in Idiopathic Pulmonary Fibrosis: Unveiling Undercover Molecular Pathways
Published in International journal of molecular sciences (27-05-2021)“…In the longtime challenge of identifying specific, easily detectable and reliable biomarkers of IPF, BALF proteomics is providing interesting new insights into…”
Get full text
Journal Article -
5
Differential Proteomic Analysis of Astrocytes and Astrocytes-Derived Extracellular Vesicles from Control and Rai Knockout Mice: Insights into the Mechanisms of Neuroprotection
Published in International journal of molecular sciences (01-08-2021)“…Reactive astrocytes are a hallmark of neurodegenerative disease including multiple sclerosis. It is widely accepted that astrocytes may adopt alternative…”
Get full text
Journal Article -
6
BAL Proteomic Signature of Lung Adenocarcinoma in IPF Patients and Its Transposition in Serum Samples for Less Invasive Diagnostic Procedures
Published in International journal of molecular sciences (04-01-2023)“…Idiopathic pulmonary fibrosis (IPF) is a form of chronic and irreversible fibrosing interstitial pneumonia of unknown etiology. Although antifibrotic…”
Get full text
Journal Article -
7
RICTOR/mTORC2 downregulation in BRAFV600E melanoma cells promotes resistance to BRAF/MEK inhibition
Published in Molecular cancer (16-05-2024)“…Abstract Background The main drawback of BRAF/MEK inhibitors (BRAF/MEKi)-based targeted therapy in the management of BRAF-mutated cutaneous metastatic melanoma…”
Get full text
Journal Article -
8
Oxidative Stress Measurement in Frozen/Thawed Human Sperm: The Protective Role of an In Vitro Treatment with Myo-Inositol
Published in Antioxidants (22-12-2021)“…Despite its widespread use, sperm cryopreservation induces serious detrimental alterations in sperm function; indeed, it is commonly associated with decreased…”
Get full text
Journal Article -
9
Multi-Omics Integrative Approach of Extracellular Vesicles: A Future Challenging Milestone
Published in Proteomes (22-04-2022)“…In the era of multi-omic sciences, dogma on singular cause-effect in physio-pathological processes is overcome and system biology approaches have been…”
Get full text
Journal Article -
10
Serum Proteomic Profile of Asthmatic Patients after Six Months of Benralizumab and Mepolizumab Treatment
Published in Biomedicines (24-03-2022)“…Severe eosinophilic asthma is characterized by chronic airway inflammation, oxidative stress, and elevated proinflammatory cytokines, especially IL-5…”
Get full text
Journal Article -
11
First Attempt to Couple Proteomics with the AhR Reporter Gene Bioassay in Soil Pollution Monitoring and Assessment
Published in Toxics (Basel) (29-12-2021)“…A topsoil sample obtained from a highly industrialized area (Taranto, Italy) was tested on the DR-CALUX cell line and the exposed cells processed with…”
Get full text
Journal Article -
12
Proteomics coupled with AhR-reporter gene bioassay for human and environmental safety assessment of sewage sludge and hydrochar
Published in The Science of the total environment (15-09-2023)“…Today application of sewage sludge (SL) and hydrochar (HC) in agriculture is a common practice for soil conditioning and crop fertilization, however safety…”
Get full text
Journal Article -
13
Ceruloplasmin and oxidative stress in severe eosinophilic asthma patients treated with Mepolizumab and Benralizumab
Published in Biochimica et biophysica acta. Proteins and proteomics (01-02-2021)“…Severe eosinophilic asthma has been associated with Th2 airway inflammation and elevated proinflammatory cytokines and chemokines, such as IL-5. Precision…”
Get full text
Journal Article -
14
Protein Extraction Methods Suitable for Muscle Tissue Proteomic Analysis
Published in Proteomes (25-09-2024)“…Muscle tissue is one of the most dynamic and plastic tissues of the mammalian body and covers different roles, such as force generation and metabolic control…”
Get full text
Journal Article -
15
A Novel Ex Vivo Approach Based on Proteomics and Biomarkers to Evaluate the Effects of Chrysene, MEHP, and PBDE-47 on Loggerhead Sea Turtles ( Caretta caretta )
Published in International journal of environmental research and public health (05-04-2022)“…The principal aim of the present study was to develop and apply novel ex vivo tests as an alternative to cell cultures able to evaluate the possible effects of…”
Get full text
Journal Article -
16
Cognitive impairment and CSF proteome modification after oral bacteriotherapy in HIV patients
Published in Journal of neurovirology (01-02-2020)“…Objective: To investigate whether a probiotic supplementation to cART patients modifies the cerebrospinal fluid (CSF) proteome and improves neurocognitive…”
Get full text
Journal Article -
17
RICTOR/mTORC2 downregulation in BRAF V600E melanoma cells promotes resistance to BRAF/MEK inhibition
Published in Molecular cancer (16-05-2024)“…The main drawback of BRAF/MEK inhibitors (BRAF/MEKi)-based targeted therapy in the management of BRAF-mutated cutaneous metastatic melanoma (MM) is the…”
Get full text
Journal Article -
18
Alteration of Serum Proteome in Levo-Thyroxine-Euthyroid Thyroidectomized Patients
Published in Journal of clinical medicine (17-03-2022)“…The monotherapy with levo-thyroxine (LT4) is the treatment of choice for patients with hypothyroidism after thyroidectomy. However, many athyreotic LT4-treated…”
Get full text
Journal Article