Search Results - "Shaabani, Shabnam"

Cobalt(II) phthalocyanine covalently anchored to cellulose as a recoverable and efficient catalyst for the aerobic oxidation of alkyl arenes and alcohols by Shaabani, Ahmad, Keshipour, Sajjad, Hamidzad, Mona, Shaabani, Shabnam

“…•Cobalt(II) phthalocyanine covalently immobilized on cellulose as a heterogeneous catalyst was synthesized.•Cobalt(II) phthalocyanine oxidized alkyl arenes and…”
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Bioactive Macrocyclic Inhibitors of the PD‐1/PD‐L1 Immune Checkpoint by Magiera‐Mularz, Katarzyna, Skalniak, Lukasz, Zak, Krzysztof M., Musielak, Bogdan, Rudzinska‐Szostak, Ewa, Berlicki, Łukasz, Kocik, Justyna, Grudnik, Przemyslaw, Sala, Dominik, Zarganes‐Tzitzikas, Tryfon, Shaabani, Shabnam, Dömling, Alexander, Dubin, Grzegorz, Holak, Tad A.

“…Blockade of the immunoinhibitory PD‐1/PD‐L1 pathway using monoclonal antibodies has shown impressive results with durable clinical antitumor responses…”
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Direct-to-biology, automated, nano-scale synthesis, and phenotypic screening-enabled E3 ligase modulator discovery by Wang, Zefeng, Shaabani, Shabnam, Gao, Xiang, Ng, Yuen Lam Dora, Sapozhnikova, Valeriia, Mertins, Philipp, Krönke, Jan, Dömling, Alexander

“…Thalidomide and its analogs are molecular glues (MGs) that lead to targeted ubiquitination and degradation of key cancer proteins via the cereblon (CRBN) E3…”
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A patent review on PD-1/PD-L1 antagonists: small molecules, peptides, and macrocycles (2015-2018) by Shaabani, Shabnam, Huizinga, Harmen P S, Butera, Roberto, Kouchi, Ariana, Guzik, Katarzyna, Magiera-Mularz, Katarzyna, Holak, Tad A, Dömling, Alexander

“…The protein-protein interaction PD1/PD-L1 is an important immune checkpoint and several recently approved monoclonal antibodies show promising anti cancer…”
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TEAD–YAP Interaction Inhibitors and MDM2 Binders from DNA‐Encoded Indole‐Focused Ugi Peptidomimetics by Kunig, Verena B. K., Potowski, Marco, Akbarzadeh, Mohammad, Klika Škopić, Mateja, Santos Smith, Denise, Arendt, Lukas, Dormuth, Ina, Adihou, Hélène, Andlovic, Blaž, Karatas, Hacer, Shaabani, Shabnam, Zarganes‐Tzitzikas, Tryfon, Neochoritis, Constantinos G., Zhang, Ran, Groves, Matthew, Guéret, Stéphanie M., Ottmann, Christian, Rahnenführer, Jörg, Fried, Roland, Dömling, Alexander, Brunschweiger, Andreas

“…DNA‐encoded combinatorial synthesis provides efficient and dense coverage of chemical space around privileged molecular structures. The indole side chain of…”
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Correction: Isolation and molecular characterization of novel glucarpidases: Enzymes to improve the antibody directed enzyme pro-drug therapy for cancer treatment by Rashidi, Fatma B, Al-Qahtani, Alanod D, Bashraheel, Sara S, Shaabani, Shabnam, Groves, Matthew R, Dömling, Alexander, Goda, Sayed K

“…[This corrects the article DOI: 10.1371/journal.pone.0196254.]…”
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Natural hydroxyapatite-supported MnO2: a green heterogeneous catalyst for selective aerobic oxidation of alkylarenes and alcohols by Shaabani, Ahmad, Afaridoun, Hadi, Shaabani, Shabnam

“…Natural hydroxyapatite‐supported MnO2 (MnO2@NHAp) was easily prepared in situ from reduction of potassium permanganate with natural hydroxyapatite derived from…”
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Nanoscale, automated, high throughput synthesis and screening for the accelerated discovery of protein modifiers by Gao, Kai, Shaabani, Shabnam, Xu, Ruixue, Zarganes-Tzitzikas, Tryfon, Gao, Li, Ahmadianmoghaddam, Maryam, Groves, Matthew R, Dömling, Alexander

“…Hit finding in early drug discovery is often based on high throughput screening (HTS) of existing and historical compound libraries, which can limit chemical…”
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Two-Step Macrocycle Synthesis by Classical Ugi Reaction by Abdelraheem, Eman M. M, Khaksar, Samad, Kurpiewska, Katarzyna, Kalinowska-Tłuścik, Justyna, Shaabani, Shabnam, Dömling, Alexander

“…The direct nonpeptidic macrocycle synthesis of α-isocyano-ω-amines via the classical Ugi four-component reaction (U-4CR) is introduced. Herein an efficient and…”
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Editorial: Isocyanide-Based Multicomponent Reactions by Rudick, Jonathan G, Shaabani, Shabnam, Dömling, Alexander

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A One-Pot Synthesis of Oxazepine-Quinazolinone bis-Heterocyclic Scaffolds via Isocyanide-Based Three-Component Reactions by Shaabani, Shabnam, Shaabani, Ahmad, Kucerakova, Monika, Dusek, Michal

“…A novel, efficient and environmentally friendly approach has been developed for the synthesis of biologically important bis -heterocyclic…”
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Novel SK channel positive modulators prevent ferroptosis and excitotoxicity in neuronal cells by Zhang, Yuequ, Shaabani, Shabnam, Vowinkel, Kirsty, Trombetta-Lima, Marina, Sabogal-Guáqueta, Angélica María, Chen, Tingting, Hoekstra, Jan, Lembeck, Jan, Schmidt, Martina, Decher, Niels, Dömling, Alexander, Dolga, Amalia M.

“…Small conductance calcium-activated potassium (SK) channel activity has been proposed to play a role in the pathology of several neurological diseases. Besides…”
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A bagasse-supported magnetic manganese dioxide nanoparticle: applications in the selective aerobic oxidation of alcohols and one-pot tandem oxidative synthesis of quinazolinones by Rashidi Vahid, Adina, Hajishaabanha, Fatemeh, Shaabani, Shabnam, Farhid, Hassan, Shaabani, Ahmad

“…Magnetic manganese dioxide nanoparticles (MnO 2 -Fe 3 O 4 ) were coated on sugarcane bagasse as a sugar industrial waste and bio-support (MnO 2 -Fe 3 O 4…”
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Biphenyl Ether Analogs Containing Pomalidomide as Small-Molecule Inhibitors of the Programmed Cell Death-1/Programmed Cell Death-Ligand 1 Interaction by Shaabani, Shabnam, Gadina, Louis, Surmiak, Ewa, Wang, Zefeng, Zhang, Bidong, Butera, Roberto, Zarganes-Tzitzikas, Tryfon, Rodriguez, Ismael, Kocik-Krol, Justyna, Magiera-Mularz, Katarzyna, Skalniak, Lukasz, Dömling, Alexander, Holak, Tad A

“…New biphenyl-based chimeric compounds containing pomalidomide were developed and evaluated for their activity to inhibit and degrade the programmed cell…”
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Isolation and molecular characterization of novel glucarpidases: Enzymes to improve the antibody directed enzyme pro-drug therapy for cancer treatment by Rashidi, Fatma B, AlQhatani, Alanod D, Bashraheel, Sara S, Shaabani, Shabnam, Groves, Matthew R, Dömling, Alexander, Goda, Sayed K

“…Repeated cycles of antibody-directed enzyme pro-drug therapy (ADEPT) and the use of glucarpidase in the detoxification of cytotoxic methotrexate (MTX) are…”
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Ugi Multicomponent Reaction Based Synthesis of Medium-Sized Rings by Abdelraheem, Eman M. M., Madhavachary, Rudrakshula, Rossetti, Arianna, Kurpiewska, Katarzyna, Kalinowska-Tłuścik, Justyna, Shaabani, Shabnam, Dömling, Alexander

“…An Ugi multicomponent reaction based two-step strategy was applied to generate medium-sized rings. In the first linear expansion phase, a series of diamines…”
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Acoustic Droplet Ejection Enabled Automated Reaction Scouting by Wang, Yuanze, Shaabani, Shabnam, Ahmadianmoghaddam, Maryam, Gao, Li, Xu, Ruixue, Kurpiewska, Katarzyna, Kalinowska-Tluscik, Justyna, Olechno, Joe, Ellson, Richard, Kossenjans, Michael, Helan, Victoria, Groves, Matthew, Dömling, Alexander

“…Miniaturization and acceleration of synthetic chemistry are critically important for rapid property optimization in pharmaceutical, agrochemical, and materials…”
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Synthesis of imidazolium zwitterions via an efficient one-pot three-component synthetic protocol by Hajishaabanha, Fatemeh, Shaabani, Shabnam, Shaabani, Ahmad, Sangachin, Mona Hamidzad, Dusek, Michal, Kučeráková, Monika

“…An efficient protocol was developed to access a new class of imidazolium zwitterions via a one-pot three-component reaction. The reaction of 1,2-diketones, α…”
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A two-step synthesis of 1,5-disubstituted tetrazoles containing a siloxy or sulfonamide group by Sarvary, Afshin, Shaabani, Shabnam, Shaabani, Ahmad, Ng, SeikWeng

“…A simple two-step route to the synthesis of 1,5-disubstituted tetrazoles containing a β-siloxy or β-sulfonamide group is presented. The synthesis takes place…”
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A Rapid Combinatorial Library Synthesis of Benzazolo[2,1-b]quinazolinones and Triazolo[2,1-b]quinazolinones by Ahmad Shaabani, Elham Farhangi, Shabnam Shaabani

“…Benzazolo [2,1-b]quinazolinones and triazolo[2,1-b]quinazolinones were synthesized in high yields by the condensation reaction of an aldehyde and a cyclic …”
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