Search Results - "Sha, Jiahao"

Complete Meiosis from Embryonic Stem Cell-Derived Germ Cells In Vitro by Zhou, Quan, Wang, Mei, Yuan, Yan, Wang, Xuepeng, Fu, Rui, Wan, Haifeng, Xie, Mingming, Liu, Mingxi, Guo, Xuejiang, Zheng, Ying, Feng, Guihai, Shi, Qinghua, Zhao, Xiao-Yang, Sha, Jiahao, Zhou, Qi

“…In vitro generation of functional gametes is a promising approach for treating infertility, although faithful replication of meiosis has proven to be a…”
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Oocyte stage-specific effects of MTOR determine granulosa cell fate and oocyte quality in mice by Guo, Jing, Zhang, Teng, Guo, Yueshuai, Sun, Tao, Li, Hui, Zhang, Xiaoyun, Yin, Hong, Cao, Guangyi, Yin, Yaoxue, Wang, Hao, Shi, Lanying, Guo, Xuejiang, Sha, Jiahao, Eppig, John J., Su, You-Qiang

“…MTOR (mechanistic target of rapamycin) is a widely recognized integrator of signals and pathways key for cellular metabolism, proliferation, and…”
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Autophagy and apoptosis act as partners to induce germ cell death after heat stress in mice by Zhang, Mianqiu, Jiang, Min, Bi, Ye, Zhu, Hui, Zhou, Zuomin, Sha, Jiahao

“…Testicular heating suppresses spermatogenesis which is marked by germ cell loss via apoptotic pathways. Recently, it is reported that autophagy also can be…”
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An essential role for PNLDC1 in piRNA 3＇ end trimming and male fertility in mice by Zhang, Yue, Guo, Rui, Cui, Yiqiang, Zhu, Zhiping, Zhang, Yingwen, Wu, Hao, Zheng, Bo, Yue, Qiuling, Bai, Shun, Zeng, Wentao, Guo, Xuejiang, Zhou, Zuomin, Shen, Bin, Zheng, Ke, Liu, Mingxi, Ye, Lan, Sha, Jiahao

“…Dear Editor, PIWI-interacting RNAs （piRNAs） are germ cell-specific small non-coding RNAs that are essential for silenc- ing transposable elements. Substantial…”
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PPM1A regulates antiviral signaling by antagonizing TBK1-mediated STING phosphorylation and aggregation by Li, Zexing, Liu, Ge, Sun, Liwei, Teng, Yan, Guo, Xuejiang, Jia, Jianhang, Sha, Jiahao, Yang, Xiao, Chen, Dahua, Sun, Qinmiao

“…Stimulator of interferon genes (STING, also known as MITA and ERIS) is critical in protecting the host against DNA pathogen invasion. However, the molecular…”
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Dual functions for the ssDNA-binding protein RPA in meiotic recombination by Shi, Baolu, Xue, Jiangyang, Yin, Hao, Guo, Rui, Luo, Mengcheng, Ye, Lan, Shi, Qinghua, Huang, Xiaoyan, Liu, Mingxi, Sha, Jiahao, Wang, P Jeremy

“…Meiotic recombination permits exchange of genetic material between homologous chromosomes. The replication protein A (RPA) complex, the predominant…”
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Early second-trimester serum miRNA profiling predicts gestational diabetes mellitus by Zhao, Chun, Dong, Jing, Jiang, Tao, Shi, Zhonghua, Yu, Bin, Zhu, Yunlong, Chen, Daozhen, Xu, Junrong, Huo, Ran, Dai, Juncheng, Xia, Yankai, Pan, Shiyang, Hu, Zhibin, Sha, Jiahao

“…Gestational diabetes mellitus (GDM) is one type of diabetes that presents during pregnancy and significantly increases the risk of a number of adverse…”
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Systematic identification of genes with a cancer-testis expression pattern in 19 cancer types by Wang, Cheng, Gu, Yayun, Zhang, Kai, Xie, Kaipeng, Zhu, Meng, Dai, Ningbin, Jiang, Yue, Guo, Xuejiang, Liu, Mingxi, Dai, Juncheng, Wu, Linxiang, Jin, Guangfu, Ma, Hongxia, Jiang, Tao, Yin, Rong, Xia, Yankai, Liu, Li, Wang, Shouyu, Shen, Bin, Huo, Ran, Wang, Qianghu, Xu, Lin, Yang, Liuqing, Huang, Xingxu, Shen, Hongbing, Sha, Jiahao, Hu, Zhibin

“…Cancer-testis ( CT ) genes represent the similarity between the processes of spermatogenesis and tumorigenesis. It is possible that their selective expression…”
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TCTE1 is a conserved component of the dynein regulatory complex and is required for motility and metabolism in mouse spermatozoa by Castaneda, Julio M., Hua, Rong, Miyata, Haruhiko, Oji, Asami, Guo, Yueshuai, Cheng, Yiwei, Zhou, Tao, Guo, Xuejiang, Cui, Yiqiang, Shen, Bin, Wang, Zibin, Hu, Zhibin, Zhou, Zuomin, Sha, Jiahao, Prunskaite-Hyyrylainen, Renata, Yu, Zhifeng, Ramirez-Solis, Ramiro, Ikawa, Masahito, Matzuk, Martin M., Liu, Mingxi

“…Flagella and cilia are critical cellular organelles that provide a means for cells to sense and progress through their environment. The central component of…”
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A homozygous FANCM frameshift pathogenic variant causes male infertility by Yin, Hao, Ma, Hui, Hussain, Sajjad, Zhang, Huan, Xie, Xuefeng, Jiang, Long, Jiang, Xiaohua, Iqbal, Furhan, Bukhari, Ihtisham, Jiang, Hanwei, Ali, Asim, Zhong, Liangwen, Li, Tao, Fan, Suixing, Zhang, Beibei, Gao, Jianing, Li, Yang, Nazish, Jabeen, Khan, Teka, Khan, Manan, Zubair, Muhammad, Hao, Qiaomei, Fang, Hui, Huang, Jun, Huleihel, Mahmoud, Sha, Jiahao, Pandita, Tej K., Zhang, Yuanwei, Shi, Qinghua

“…Fanconi anemia (FA) genes play important roles in spermatogenesis. In mice, disruption of Fancm impairs male fertility and testicular integrity, but whether…”
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In vitro testicular organogenesis from human fetal gonads produces fertilization-competent spermatids by Yuan, Yan, Li, Laihua, Cheng, Qing, Diao, Feiyang, Zeng, Qiao, Yang, Xiaoyu, Wu, Yibo, Zhang, Hao, Huang, Mingqian, Chen, Junqing, Zhou, Quan, Zhu, Yunfei, Hua, Rong, Tian, Jianyu, Wang, Xin, Zhou, Zuomin, Hao, Jie, Yu, Jinjin, Hua, Dong, Liu, Jiayin, Guo, Xuejiang, Zhou, Qi, Sha, Jiahao

“…Unlike most organs that mature during the fetal period, the male reproductive system reaches maturity only at puberty with the commencement of spermatogenesis…”
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mUbiSiDa: a comprehensive database for protein ubiquitination sites in mammals by Chen, Tong, Zhou, Tao, He, Bing, Yu, Haiyan, Guo, Xuejiang, Song, Xiaofeng, Sha, Jiahao

“…Protein ubiquitination is one of the important post-translational modifications by attaching ubiquitin to specific lysine (K) residues in target proteins, and…”
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Major spliceosome defects cause male infertility and are associated with nonobstructive azoospermia in humans by Wu, Hao, Sun, Liwei, Wen, Yang, Liu, Yujuan, Yu, Jun, Mao, Feiyu, Wang, Ya, Tong, Chao, Guo, Xuejiang, Hu, Zhibin, Sha, Jiahao, Liu, Mingxi, Xia, Laixin

“…Processing of pre-mRNA into mRNA is an important regulatory mechanism in eukaryotes that is mediated by the spliceosome, a huge and dynamic ribonucleoprotein…”
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Rapid evolution of mammalian X-linked testis microRNAs by Guo, Xuejiang, Su, Bing, Zhou, Zuomin, Sha, Jiahao

“…MicroRNAs (miRNAs), which are small, non-coding RNAs approximately 21-nucleotides in length, have become a major focus of research in molecular biology…”
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Association of assisted reproductive technology, germline de novo mutations and congenital heart defects in a prospective birth cohort study by Wang, Cheng, Lv, Hong, Ling, Xiufeng, Li, Hong, Diao, Feiyang, Dai, Juncheng, Du, Jiangbo, Chen, Ting, Xi, Qi, Zhao, Yang, Zhou, Kun, Xu, Bo, Han, Xiumei, Liu, Xiaoyu, Peng, Meijuan, Chen, Congcong, Tao, Shiyao, Huang, Lei, Liu, Cong, Wen, Mingyang, Jiang, Yangqian, Jiang, Tao, Lu, Chuncheng, Wu, Wei, Wu, Di, Chen, Minjian, Lin, Yuan, Guo, Xuejiang, Huo, Ran, Liu, Jiayin, Ma, Hongxia, Jin, Guangfu, Xia, Yankai, Sha, Jiahao, Shen, Hongbing, Hu, Zhibin

“…Emerging evidence suggests that children conceived through assisted reproductive technology (ART) have a higher risk of congenital heart defects (CHDs) even…”
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Lack of testicular seipin causes teratozoospermia syndrome in men by Jiang, Min, Gao, Mingming, Wu, Chaoming, He, Hui, Guo, Xuejiang, Zhou, Zuomin, Yang, Hongyuan, Xiao, Xinhua, Liu, George, Sha, Jiahao

“…Obesity impairs male fertility, providing evidence for a link between adipose tissue and reproductive function; however, potential consequences of adipose…”
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Multi-Omics Approaches for Revealing the Epigenetic Regulation of Histone H3.1 during Spermatogonial Stem Cell Differentiation In Vitro by Liu, Li, Li, Haojie, Wang, Mengjie, Zhang, Xiangzheng, Ren, Jie, Yuan, Yan, Sha, Jiahao, Guo, Xuejiang

“…Epigenetic regulation, particularly post-translational modifications (PTMs) of histones, participates in spermatogonial stem cell (SSCs) differentiation…”
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Generation of a precise Oct4-hrGFP knockin cynomolgus monkey model via CRISPR/Cas9-assisted homologous recombination by Cui, Yiqiang, Niu, Yuyu, Zhou, Jiankui, Chen, Yongchang, Cheng, Yiwei, Li, Shangang, Ai, Zongyong, Chu, Chu, Wang, Hong, Zheng, Bo, Chen, Xuejin, Sha, Jiahao, Guo, Xuejiang, Huang, Xingxu, Ji, Weizhi

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A novel protein encoded by circRsrc1 regulates mitochondrial ribosome assembly and translation during spermatogenesis by Zhang, Shu, Wang, Chang, Wang, Yue, Zhang, Hao, Xu, Chen, Cheng, Yiwei, Yuan, Yan, Sha, Jiahao, Guo, Xuejiang, Cui, Yiqiang

“…Circular RNAs (circRNAs) are a large class of mammalian RNAs. Several protein products translated by circRNAs have been reported to be involved in the…”
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Downregulation of miR‐106b induced breast cancer cell invasion and motility in association with overexpression of matrix metalloproteinase 2 by Ni, Xiaojian, Xia, Tiansong, Zhao, Yingchun, Zhou, Wenbin, Wu, Naping, Liu, Xiaoan, Ding, Qiang, Zha, Xiaoming, Sha, Jiahao, Wang, Shui

“…Breast cancer (BC) is one of the most common cancers in women, and it can often metastasize to the bone. The mechanism of BC bone metastasis remains unclear…”
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