Search Results - "Sgarra, Luca"

Activation of AMPK/SIRT1 axis is required for adiponectin-mediated preconditioning on myocardial ischemia-reperfusion (I/R) injury in rats by Potenza, Maria Assunta, Sgarra, Luca, Nacci, Carmela, Leo, Valentina, De Salvia, Maria Antonietta, Montagnani, Monica

“…Adiponectin (AD) cardioprotective activities are mediated by AMPK, a fuel-sensing molecule sharing common targets and cellular activities with SIRT-1. Whether…”
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The Intrinsic Virtues of EGCG, an Extremely Good Cell Guardian , on Prevention and Treatment of Diabesity Complications by Potenza, Maria Assunta, Iacobazzi, Dominga, Sgarra, Luca, Montagnani, Monica

“…The pandemic proportion of diabesity-a combination of obesity and diabetes-sets a worldwide health issue. Experimental and clinical studies have progressively…”
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Diabetes and Alzheimer’s Disease: Might Mitochondrial Dysfunction Help Deciphering the Common Path? by Potenza, Maria Assunta, Sgarra, Luca, Desantis, Vanessa, Nacci, Carmela, Montagnani, Monica

“…A growing number of clinical and epidemiological studies support the hypothesis of a tight correlation between type 2 diabetes mellitus (T2DM) and the…”
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microRNAs as Biomarkers of Endothelial Dysfunction and Therapeutic Target in the Pathogenesis of Atrial Fibrillation by Desantis, Vanessa, Potenza, Maria Assunta, Sgarra, Luca, Nacci, Carmela, Scaringella, Antonietta, Cicco, Sebastiano, Solimando, Antonio Giovanni, Vacca, Angelo, Montagnani, Monica

“…The pathophysiology of atrial fibrillation (AF) may involve atrial fibrosis/remodeling and dysfunctional endothelial activities. Despite the currently…”
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Can Epigenetics of Endothelial Dysfunction Represent the Key to Precision Medicine in Type 2 Diabetes Mellitus? by Coco, Celeste, Sgarra, Luca, Potenza, Maria Assunta, Nacci, Carmela, Pasculli, Barbara, Barbano, Raffaela, Parrella, Paola, Montagnani, Monica

“…In both developing and industrialized Countries, the growing prevalence of Type 2 Diabetes Mellitus (T2DM) and the severity of its related complications make…”
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Antibiotic Prophylaxis and Treatment for Cardiac Device Infections by Pandozi, Claudio, Matteucci, Andrea, Pignalberi, Carlo, Sgarra, Luca, Bonanni, Michela, Mariani, Marco Valerio, La Fazia, Vincenzo Mirco, Nesti, Lorenzo, Di Fusco, Stefania Angela, Nardi, Federico, Colivicchi, Furio

“…Cardiac device infections (CDIs) are a serious complication in patients with implanted devices, resulting in increased morbidity, prolonged hospital stay, and…”
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Intermittent losartan administration triggers cardiac post-conditioning in isolated rat hearts: role of BK2 receptors by Sgarra, Luca, Leo, Valentina, Addabbo, Francesco, Iacobazzi, Dominga, Carratù, Maria Rosaria, Montagnani, Monica, Potenza, Maria Assunta

“…The angiotensin (Ang) and bradykinin (BK) tissue-system plays a pivotal role in post-conditioning, but the efficacy of angiotensin type 1 receptor (AT1R)…”
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Endothelial Dysfunction May Link Interatrial Septal Abnormalities and MTHFR-Inherited Defects to Cryptogenic Stroke Predisposition by Sgarra, Luca, Bortone, Alessandro Santo, Potenza, Maria Assunta, Nacci, Carmela, De Salvia, Maria Antonietta, Acquaviva, Tommaso, De Cillis, Emanuela, Ciccone, Marco Matteo, Grimaldi, Massimo, Montagnani, Monica

“…We explored the significance of the L-Arginine/asymmetric dimethylarginine (L-Arg/ADMA) ratio as a biomarker of endothelial dysfunction in stroke patients. To…”
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Targeting endothelial metaflammation to counteract diabesity cardiovascular risk: Current and perspective therapeutic options by Potenza, Maria Assunta, Nacci, Carmela, De Salvia, Maria Antonietta, Sgarra, Luca, Collino, Massimo, Montagnani, Monica

“…[Display omitted] The association of obesity and diabetes, termed “diabesity”, defines a combination of primarily metabolic disorders with insulin resistance…”
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Left atrial strain is a good predictor of atrio‐ventricular synchrony in leadless pacemaker pacing by Troisi, Federica, Caccavo, Vincenzo P., Santobuono, Vincenzo E., Sgarra, Luca, Carella, Maria C., Basile, Paolo, Guaricci, Andrea I., Grimaldi, Massimo

“…Introduction The importance of atrio‐ventricular synchrony pacing in sinus rhythm patients is known. To identify patients in whom leadless pacemakers are able…”
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Activation of AMPK/SIRT1 axis is required for adiponectin-mediated preconditioning on myocardial ischemia-reperfusion by Potenza, Maria Assunta, Sgarra, Luca, Nacci, Carmela, Leo, Valentina, De Salvia, Maria Antonietta, Montagnani, Monica

“…Background Adiponectin (AD) cardioprotective activities are mediated by AMPK, a fuel-sensing molecule sharing common targets and cellular activities with…”
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812 FOLATES-RELATED ERYTHROCYTE DIVERSION LEAD TO ATRIAL CARDIOMYOPATHY/FIBRILLATION THROUGH EPCS DYSFUNCTION by Sgarra, Luca, Desantis, Vanessa, Potenza, Maria Assunta, Montagnani, Monica, Grimaldi, Massimo

“…Abstract Background Recent advances support the concept that pre-persistent Atrial Fibrillation (AF) and paradoxical embolism do not explain the wholeness of…”
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Determinants of evolving metabolic and cardiovascular benefit/risk profiles of rosiglitazone therapy during the natural history of diabetes: molecular mechanisms in the context of integrated pathophysiology by Sgarra, Luca, Addabbo, Francesco, Potenza, Maria Assunta, Montagnani, Monica

“…Rosiglitazone is a thiazolidinedione, a synthetic PPARγ receptor agonist with insulin-sensitizing properties that is used as an antidiabetic drug. In addition…”
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Infliximab therapy restores adiponectin expression in perivascular adipose tissue and improves endothelial nitric oxide-mediated vasodilation in mice with type 1 diabetes by Nacci, Carmela, Leo, Valentina, De Benedictis, Leonarda, Potenza, Maria A, Sgarra, Luca, De Salvia, Maria A, Quon, Michael J, Montagnani, Monica

“…Abstract Increased TNFα-mediated JNK signaling in the perivascular adipose tissue (PVAT) may contribute to the pathogenesis of vascular complications in T1DM…”
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An atypical pseudoaneurysm as complication of prosthetic aortic-valve endocarditis by Guaricci, Andrea I, Musci, Rita L, Santis, Delia De, Argentiero, Donatella, Sgarra, Luca, Losito, Concetta, Marangelli, Vito, Nacci, Frida, Zanna, Domenico, Favale, Stefano

“…Endocarditis of a prosthetic heart valve is a life-threatening condition that is associated with high morbidity and mortality. Perivalvular extension in…”
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Aortic coarctation: guidelines mismatch across the ocean by Pepe, Martino, Iacovelli, Fortunato, Masi, Filippo, Marangelli, Vito, Scardapane, Arnaldo, De Santis, Alessandro, Sgarra, Luca, Quagliara, Donato, Favale, Stefano

“…Pseudocoarctation is a rare congenital anomaly characterized by aorta elongation and kinking, without significant obstruction. We report the case of an elderly…”
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