Search Results - "Sferra, T J"
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Recombinant AAV serotype 1 transduction efficiency and tropism in the murine brain
Published in Gene therapy (01-08-2003)“…Recombinant adeno-associated virus serotype 2 (rAAV2) vectors have shown promise as therapeutic agents for neurologic disorders. However, intracerebral…”
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Outcomes of Clostridium difficile infection in pediatric solid organ transplant recipients
Published in Transplant infectious disease (01-02-2016)“…Background The incidence of Clostridium difficile infection (CDI) is increasing in the pediatric population. Pediatric recipients of solid organ…”
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Association of Clostridium difficile infection with outcomes of hospitalized solid organ transplant recipients: results from the 2009 Nationwide Inpatient Sample database
Published in Transplant infectious disease (01-10-2012)“…Background Diarrhea is a frequent and potentially severe complication in solid organ transplant (SOT) recipients. One of the most common infectious etiologies…”
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Recombinant adeno-associated virus-mediated correction of lysosomal storage within the central nervous system of the adult mucopolysaccharidosis type VII mouse
Published in Human gene therapy (01-03-2000)“…The central nervous system (CNS) is a predominant site of involvement in several lysosomal storage diseases (LSDs); and for many patients, these diseases are…”
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A phase I study of adenovirus-mediated transfer of the human cystic fibrosis transmembrane conductance regulator gene to a lung segment of individuals with cystic fibrosis
Published in Human gene therapy (10-12-1999)“…A third-generation adenoviral vector containing recombinant human cystic fibrosis transmembrane conductance regulator (CFTR) gene was delivered by bronchoscope…”
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Expression and activity of human Na+/I- symporter in human glioma cells by adenovirus-mediated gene delivery
Published in Gene therapy (01-05-2000)“…Radioiodide concentrating activity in the thyroid, mediated by human Na+/I- symporter (hNIS), provides a mechanism for effective radioiodide treatment for…”
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Ménétrier disease of childhood: Role of cytomegalovirus and transforming growth factor alpha
Published in The Journal of pediatrics (01-02-1996)“…OBJECTIVE: Because the role of cytomegalovirus in Ménétrier disease in children remains unclear and recent studies have implicated transforming growth factor…”
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Characterization of the cystic fibrosis transmembrane conductance regulator promoter region. Chromatin context and tissue-specificity
Published in The Journal of biological chemistry (25-07-1993)“…Expression of the gene encoding the cystic fibrosis transmembrane conductance regulator (CFTR) is tightly regulated. Using a panel of cell lines expressing…”
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ESCHERICHIA COLI ARTHRITIS AS THE PRESENTING MANIFESTATION OF POSTERIOR URETHRAL VALVES
Published in The Pediatric infectious disease journal (01-02-1997)“…We report a youngster with urosepsis and pyogenic E. coli arthritis which was the presenting manifestation of posterior urethral valves…”
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Gastrointestinal gas formation and infantile colic
Published in The Pediatric clinics of North America (01-04-1996)“…Gastrointestinal gas causes distress in many patients and their parents. Most often, patients do not have an actual increase in gastrointestinal gas volume,…”
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Adeno-associated virus-mediated gene transfer to the brain: duration and modulation of expression
Published in Human gene therapy (20-01-1999)“…Adeno-associated virus (AAV) is a promising vector for central nervous system (CNS) gene transfer, but a number of issues must be addressed if AAV is to be…”
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Simultaneous recovery of bacterial and viral pathogens from cerebrospinal fluid
Published in The Pediatric infectious disease journal (01-08-1988)“…Mixed bacterial infection in meningitis is well-documented, but there have been few previous reports of mixed viral-bacterial meningitis. A retrospective…”
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Recombinant adeno-associated viral vectors mediate long-term transgene expression in muscle
Published in Human gene therapy (10-04-1997)“…Gene transfer to muscle holds overt promise for the treatment of inherited myopathies, lysosomal storage disorders, and serum protein deficiencies. In…”
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The Molecular Biology of Cystic Fibrosis
Published in Annual review of medicine (1993)“…Cystic fibrosis afflicts many children and, as the life expectancy for patients with this disease steadily increases, many adults as well. The identification…”
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Microsphere-adenoviral complexes target and transduce the glomerulus in vivo
Published in Kidney international (01-10-2000)“…Microsphere-adenoviral complexes target and transduce the glomerulus in vivo. Developing new treatments for glomerulonephritis makes the glomerulus a logical…”
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Gene transfer to the intestinal tract: a new approach using selective injection of the superior mesenteric artery
Published in Human gene therapy (10-04-1997)“…Gene transfer to the intestinal tract has many potential applications, including complementation of single gene disorders, genetic immunization, and ectopic…”
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Gene Transfer into the CNS Using Recombinant Adeno-associated Virus: Analysis of Vector DNA Forms Resulting in Sustained Expression
Published in Journal of drug targeting (01-01-1999)“…Abstract Recombinant adeno-associated virus (rAAV) vectors have shown significant promise as vehicles for in vivo gene transfer, particularly for transduction…”
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Successful DNA transfer in cultured human mesangial cells using replication deficient recombinant adenovirus
Published in Journal of investigative medicine (01-06-1998)“…Efficient transfer of DNA into human mesangial cells is an essential first step in the development of gene therapies for mesangial cell-mediated…”
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Molecular Characterization of Adeno-Associated Viruses Infecting Children
Published in Journal of Virology (01-12-2005)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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