Search Results - "Sezerman, Uğur"

CogNet: classification of gene expression data based on ranked active-subnetwork-oriented KEGG pathway enrichment analysis by Yousef, Malik, Ülgen, Ege, Uğur Sezerman, Osman

“…Most of the traditional gene selection approaches are borrowed from other fields such as statistics and computer science, However, they do not prioritize…”
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Base-excess chloride; the best approach to evaluate the effect of chloride on the acid-base status: A retrospective study by Gucyetmez, Bulent, Tuzuner, Filiz, Atalan, Hakan Korkut, Sezerman, Uğur, Gucyetmez, Kaan, Telci, Lutfi

“…To practically determine the effect of chloride (Cl) on the acid-base status, four approaches are currently used: accepted ranges of serum Cl values; Cl…”
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Identification of an epilepsy-linked gut microbiota signature in a pediatric rat model of acquired epilepsy by Riva, Antonella, Sahin, Eray, Volpedo, Greta, Petretto, Andrea, Lavarello, Chiara, Di Sapia, Rossella, Barbarossa, Davide, Zaniani, Nasibeh Riahi, Craparotta, Ilaria, Barbera, Maria Chiara, Sezerman, Uğur, Vezzani, Annamaria, Striano, Pasquale, Ravizza, Teresa

“…A dysfunctional gut microbiota-brain axis is emerging as a potential pathogenic mechanism in epilepsy, particularly in pediatric forms of epilepsy. To add new…”
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Computational analysis of missense filamin-A variants, including the novel p.Arg484Gln variant of two brothers with periventricular nodular heterotopia by Gerlevik, Umut, Saygı, Ceren, Cangül, Hakan, Kutlu, Aslı, Çaralan, Erdal Fırat, Topçu, Yasemin, Özören, Nesrin, Sezerman, Osman Uğur

“…Periventricular nodular heterotopia (PNH) is a cell migration disorder associated with mutations in Filamin-A (FLNA) gene on chromosome X. Majority of the…”
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Adaptive phenotypic modulations lead to therapy resistance in chronic myeloid leukemia cells by Baykal-Köse, Seda, Acikgoz, Eda, Yavuz, Ahmet Sinan, Gönül Geyik, Öykü, Ateş, Halil, Sezerman, Osman Uğur, Özsan, Güner Hayri, Yüce, Zeynep

“…Tyrosine kinase inhibitor (TKI) resistance is a major problem in chronic myeloid leukemia (CML). We generated a TKI-resistant K562 sub-population, K562-IR,…”
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Endometrial gene expression profiling of recurrent implantation failure after in vitro fertilization by Albayrak, İrem Gülfem, Azhari, Fatemeh, Çolak, Ezgi Nur, Balcı, Burçin Karamustafaoğlu, Ülgen, Ege, Sezerman, Uğur, Baştu, Ercan, Günel, Tuba

“…Recurrent implantation failure (RIF) is diagnosed when good-quality embryos repeatedly fail to implant after transfer in several in vitro fertilization (IVF)…”
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Structural analysis of M1AP variants associated with severely impaired spermatogenesis causing male infertility by Gerlevik, Umut, Ergoren, Mahmut Cerkez, Sezerman, Osman Uğur, Temel, Sehime Gulsun

“…Impaired meiosis can result in absence of sperm in the seminal fluid. This condition, namely non-obstructive azoospermia (NOA), is one of the reasons of male…”
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A possible founder mutation in FZD6 gene in a Turkish family with autosomal recessive nail dysplasia by Saygı, Ceren, Alanay, Yasemin, Sezerman, Uğur, Yenenler, Aslı, Özören, Nesrin

“…Autosomal recessive nail dysplasia is characterized by thick and hard nails with a very slow growth on the hands and feet. Mutations in FZD6 gene were found to…”
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Investigating the structural properties of the active conformation BTL2 of a lipase from Geobacillus thermocatenulatus in toluene using molecular dynamic simulations and engineering BTL2 via in-silico mutation by Yenenler, Aslı, Venturini, Alessandro, Burduroglu, Huseyin Cahit, Sezerman, Osman Uğur

“…The discovery or development of thermoalkalophilic lipases that show high levels of catalytic activity in organic solvents would have important industrial…”
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Investigation of the Impact of Antibiotic Administration on the Preterm Infants' Gut Microbiome Using Next-Generation Sequencing-Based 16S rRNA Gene Analysis by Aktaş, Ahmet, Ekren, Berkay Yekta, Yaşa, Beril, Sezerman, Osman Uğur, Nakipoğlu, Yaşar

“…The human gut microbiota is an extensive population of microorganisms, and it shows significant variations between periods of optimal health and periods of…”
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Understanding thermal and organic solvent stability of thermoalkalophilic lipases: insights from computational predictions and experiments by Shehata, Mohamed, Timucin, Emel, Venturini, Alessandro, Sezerman, Osman Uğur

“…Bacillus thermocatenulatus lipase (BTL2), a member of the isolated lipase family known as thermoalkalophilic lipases, carries potential for industrial…”
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Understanding the Role of the Microbiome in Cancer Diagnostics and Therapeutics by Creating and Utilizing ML Models by Cekikj, Miodrag, Jakimovska Özdemir, Milena, Kalajdzhiski, Slobodan, Özcan, Orhan, Sezerman, Osman Uğur

“…Recent studies have highlighted that gut microbiota can alter colorectal cancer susceptibility and progression due to its impact on colorectal carcinogenesis…”
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Phenotype screens of murine pancreatic cancer identify a Tgf-α-Ccl2-paxillin axis driving human-like neural invasion by Wang, Xiaobo, Istvanffy, Rouzanna, Ye, Linhan, Teller, Steffen, Laschinger, Melanie, Diakopoulos, Kalliope N, Görgülü, Kıvanç, Li, Qiaolin, Ren, Lei, Jäger, Carsten, Steiger, Katja, Muckenhuber, Alexander, Vilne, Baiba, Çifcibaşı, Kaan, Reyes, Carmen Mota, Yurteri, Ümmügülsüm, Kießler, Maximilian, Gürçınar, Ibrahim Halil, Sugden, Maya, Yıldızhan, Saliha Elif, Sezerman, Osman Uğur, Çilingir, Sümeyye, Süyen, Güldal, Reichert, Maximilian, Schmid, Roland M, Bärthel, Stefanie, Oellinger, Rupert, Krüger, Achim, Rad, Roland, Saur, Dieter, Algül, Hana, Friess, Helmut, Lesina, Marina, Ceyhan, Güralp Onur, Demir, Ihsan Ekin

“…Solid cancers like pancreatic ductal adenocarcinoma (PDAC), a type of pancreatic cancer, frequently exploit nerves for rapid dissemination. This neural…”
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Var3PPred: variant prediction based on 3-D structure and sequence analyses of protein-protein interactions on autoinflammatory diseases by Bülbül, Alper, Timucin, Emel, Timuçin, Ahmet Can, Sezerman, Osman Ugur, Tahir Turanli, Eda

“…We developed a pathogenicity classifier, named Var3PPred, for identifying pathogenic variants in genes associated with autoinflammatory disorders. Our…”
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CSF Proteomics Identifies Specific and Shared Pathways for Multiple Sclerosis Clinical Subtypes by Avsar, Timucin, Durası, İlknur Melis, Uygunoğlu, Uğur, Tütüncü, Melih, Demirci, Nuri Onat, Saip, Sabahattin, Sezerman, O Uğur, Siva, Aksel, Tahir Turanlı, Eda

“…Multiple sclerosis (MS) is an immune-mediated, neuro-inflammatory, demyelinating and neurodegenerative disease of the central nervous system (CNS) with a…”
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Gene pathway analysis of the endometrium at the start of the window of implantation in women with unexplained infertility and unexplained recurrent pregnancy loss: is unexplained recurrent pregnancy loss a subset of unexplained infertility? by Keleş, Irem Demiral, Günel, Tuba, Özgör, Bahar Yüksel, Ülgen, Ege, Gümüşoğlu, Ece, Hosseini, Mohammad Kazem, Sezerman, Uğur, Buyru, Faruk, Yeh, John, Baştu, Ercan

“…This study aims to understand differences/similarities in the genetic profile of the endometrium at the start of window of implantation (WOI) in women with…”
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Whole exome sequencing-based analysis to identify DNA damage repair deficiency as a major contributor to gliomagenesis in adult diffuse gliomas by Ülgen, Ege, Can, Özge, Bilguvar, Kaya, Oktay, Yavuz, Akyerli, Cemaliye B, Danyeli, Ayça Erşen, Yakıcıer, M Cengiz, Sezerman, O Uğur, Pamir, M Necmettin, Özduman, Koray

“…Processes that cause or contribute to cancer, such as aging, exposure to carcinogens, or DNA damage repair deficiency (DDRd), create predictable and traceable…”
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Enhancing Enzymatic Properties of Endoglucanase I Enzyme from Trichoderma Reesei via Swapping from Cellobiohydrolase I Enzyme by Aslı Yenenler, Hasan Kurt, Osman Uğur Sezerman

“…Utilizing plant-based materials as a biofuel source is an increasingly popular attempt to redesign the global energy cycle. This endeavour underlines the…”
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Investigation of multiple sclerosis-related pathways through the integration of genomic and proteomic data by Everest, Elif, Ülgen, Ege, Uygunoglu, Ugur, Tutuncu, Melih, Saip, Sabahattin, Sezerman, Osman Ugur, Siva, Aksel, Tahir Turanli, Eda

“…Background Multiple sclerosis (MS) has a complex pathophysiology, variable clinical presentation, and unpredictable prognosis; understanding the underlying…”
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Comparison of endometrial prostanoid profiles in three infertile subgroups: the missing part of receptivity? by Demiral Keleş, Irem, Ülgen, Ege, Erkan, Melike Belkız, Çelik, Saliha Esin, Aydın, Yasemin, Önem, Ayşe Nur, Kandemir, Hülya, Arslanoğlu, Tuğçe, Apak, Mustafa Reşat, Sezerman, Uğur, Yeh, John, Buyru, Faruk, Baştu, Ercan

“…To study the prostanoid profile of the endometria of patients with recurrent implantation failure (RIF), unexplained infertility (UIF), and recurrent…”
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