Search Results - "Seymour, Christopher"

Blood, Bleeding, and Transfusion—A Theme Issue by Seymour, Christopher W.

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Time to Treatment and Mortality during Mandated Emergency Care for Sepsis by Seymour, Christopher W, Gesten, Foster, Prescott, Hallie C, Friedrich, Marcus E, Iwashyna, Theodore J, Phillips, Gary S, Lemeshow, Stanley, Osborn, Tiffany, Terry, Kathleen M, Levy, Mitchell M

“…In an analysis including nearly 50,000 patients with sepsis treated at 149 New York hospitals, more rapid delivery of a 3-hour sepsis-care bundle (a protocol…”
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A cooperation of the doves by Seymour, Christopher W.

“…It was the third hour of our conference call. More than 20 researchers were contemplating a global response to the SARS-CoV-2 pandemic. I listened to the…”
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The Ethics of Clinical Research: Managing Persistent Uncertainty by London, Alex John, Seymour, Christopher W

“…n the face of novel pathogens, incomplete knowledge, and disagreement about the merits of medical treatments, translating the duty to care into concrete…”
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Precision Medicine for COVID-19: Phenotype Anarchy or Promise Realized? by DeMerle, Kimberley, Angus, Derek C, Seymour, Christopher W

“…This Viewpoint discusses the trend toward identifying "subtypes" of various diseases (eg, asthma and COPD) and proposes criteria for justifying…”
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The global burden of sepsis: barriers and potential solutions by Rudd, Kristina E, Kissoon, Niranjan, Limmathurotsakul, Direk, Bory, Sotharith, Mutahunga, Birungi, Seymour, Christopher W, Angus, Derek C, West, T Eoin

“…Sepsis is a major contributor to the global burden of disease. The majority of sepsis cases and deaths are estimated to occur in low and middle-income…”
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Septic Shock: Advances in Diagnosis and Treatment by Seymour, Christopher W, Rosengart, Matthew R

“…IMPORTANCE: Septic shock is a clinical emergency that occurs in more than 230 000 US patients each year. OBSERVATIONS AND ADVANCES: In the setting of suspected…”
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Derivation, Validation, and Potential Treatment Implications of Novel Clinical Phenotypes for Sepsis by Seymour, Christopher W, Kennedy, Jason N, Wang, Shu, Chang, Chung-Chou H, Elliott, Corrine F, Xu, Zhongying, Berry, Scott, Clermont, Gilles, Cooper, Gregory, Gomez, Hernando, Huang, David T, Kellum, John A, Mi, Qi, Opal, Steven M, Talisa, Victor, van der Poll, Tom, Visweswaran, Shyam, Vodovotz, Yoram, Weiss, Jeremy C, Yealy, Donald M, Yende, Sachin, Angus, Derek C

“…IMPORTANCE: Sepsis is a heterogeneous syndrome. Identification of distinct clinical phenotypes may allow more precise therapy and improve care. OBJECTIVE: To…”
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Global, regional, and national sepsis incidence and mortality, 1990–2017: analysis for the Global Burden of Disease Study by Rudd, Kristina E, Johnson, Sarah Charlotte, Agesa, Kareha M, Shackelford, Katya Anne, Tsoi, Derrick, Kievlan, Daniel Rhodes, Colombara, Danny V, Ikuta, Kevin S, Kissoon, Niranjan, Finfer, Simon, Fleischmann-Struzek, Carolin, Machado, Flavia R, Reinhart, Konrad K, Rowan, Kathryn, Seymour, Christopher W, Watson, R Scott, West, T Eoin, Marinho, Fatima, Hay, Simon I, Lozano, Rafael, Lopez, Alan D, Angus, Derek C, Murray, Christopher J L, Naghavi, Mohsen

“…Sepsis is life-threatening organ dysfunction due to a dysregulated host response to infection. It is considered a major cause of health loss, but data for the…”
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Incidence and Trends of Sepsis in US Hospitals Using Clinical vs Claims Data, 2009-2014 by Rhee, Chanu, Dantes, Raymund, Epstein, Lauren, Murphy, David J, Seymour, Christopher W, Iwashyna, Theodore J, Kadri, Sameer S, Angus, Derek C, Danner, Robert L, Fiore, Anthony E, Jernigan, John A, Martin, Greg S, Septimus, Edward, Warren, David K, Karcz, Anita, Chan, Christina, Menchaca, John T, Wang, Rui, Gruber, Susan, Klompas, Michael

“…IMPORTANCE: Estimates from claims-based analyses suggest that the incidence of sepsis is increasing and mortality rates from sepsis are decreasing. However,…”
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Comparing the validity of different ICD coding abstraction strategies for sepsis case identification in German claims data by Fleischmann-Struzek, Carolin, Thomas-Rüddel, Daniel O, Schettler, Anna, Schwarzkopf, Daniel, Stacke, Angelika, Seymour, Christopher W, Haas, Christoph, Dennler, Ulf, Reinhart, Konrad

“…Administrative data are used to generate estimates of sepsis epidemiology and can serve as source for quality indicators. Aim was to compare estimates on…”
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Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3) by Seymour, Christopher W, Liu, Vincent X, Iwashyna, Theodore J, Brunkhorst, Frank M, Rea, Thomas D, Scherag, André, Rubenfeld, Gordon, Kahn, Jeremy M, Shankar-Hari, Manu, Singer, Mervyn, Deutschman, Clifford S, Escobar, Gabriel J, Angus, Derek C

“…IMPORTANCE: The Third International Consensus Definitions Task Force defined sepsis as “life-threatening organ dysfunction due to a dysregulated host response…”
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Developing a New Definition and Assessing New Clinical Criteria for Septic Shock: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3) by Shankar-Hari, Manu, Phillips, Gary S, Levy, Mitchell L, Seymour, Christopher W, Liu, Vincent X, Deutschman, Clifford S, Angus, Derek C, Rubenfeld, Gordon D, Singer, Mervyn

“…IMPORTANCE: Septic shock currently refers to a state of acute circulatory failure associated with infection. Emerging biological insights and reported…”
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Caring for Patients With Acute Respiratory Distress Syndrome: Summary of the 2023 ESICM Practice Guidelines by Angus, Derek C, Seymour, Christopher W, Bibbins-Domingo, Kirsten

“…This article summarizes the 2023 updated ARDS guidelines from the European Society of Intensive Care Medicine, including the guidelines’ methods, findings, and…”
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Current Murine Models of Sepsis by Lewis, Anthony J, Seymour, Christopher W, Rosengart, Matthew R

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Association Between the New York Sepsis Care Mandate and In-Hospital Mortality for Pediatric Sepsis by Evans, Idris V. R, Phillips, Gary S, Alpern, Elizabeth R, Angus, Derek C, Friedrich, Marcus E, Kissoon, Niranjan, Lemeshow, Stanley, Levy, Mitchell M, Parker, Margaret M, Terry, Kathleen M, Watson, R. Scott, Weiss, Scott L, Zimmerman, Jerry, Seymour, Christopher W

“…IMPORTANCE: The death of a pediatric patient with sepsis motivated New York to mandate statewide sepsis treatment in 2013. The mandate included a 1-hour bundle…”
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Interleukin-6 Receptor Antagonists in Critically Ill Patients with Covid-19 by Gordon, Anthony C, Mouncey, Paul R, Al-Beidh, Farah, Rowan, Kathryn M, Nichol, Alistair D, Arabi, Yaseen M, Annane, Djillali, Beane, Abi, van Bentum-Puijk, Wilma, Berry, Lindsay R, Bhimani, Zahra, Bonten, Marc J M, Bradbury, Charlotte A, Brunkhorst, Frank M, Buzgau, Adrian, Cheng, Allen C, Detry, Michelle A, Duffy, Eamon J, Estcourt, Lise J, Fitzgerald, Mark, Goossens, Herman, Haniffa, Rashan, Higgins, Alisa M, Hills, Thomas E, Horvat, Christopher M, Lamontagne, Francois, Lawler, Patrick R, Leavis, Helen L, Linstrum, Kelsey M, Litton, Edward, Lorenzi, Elizabeth, Marshall, John C, Mayr, Florian B, McAuley, Daniel F, McGlothlin, Anna, McGuinness, Shay P, McVerry, Bryan J, Montgomery, Stephanie K, Morpeth, Susan C, Murthy, Srinivas, Orr, Katrina, Parke, Rachael L, Parker, Jane C, Patanwala, Asad E, Pettilä, Ville, Rademaker, Emma, Santos, Marlene S, Saunders, Christina T, Seymour, Christopher W, Shankar-Hari, Manu, Sligl, Wendy I, Turgeon, Alexis F, Turner, Anne M, van de Veerdonk, Frank L, Zarychanski, Ryan, Green, Cameron, Lewis, Roger J, Angus, Derek C, McArthur, Colin J, Berry, Scott, Webb, Steve A, Derde, Lennie P G

“…The interleukin-6 receptor blockers tocilizumab and sarilumab were tested against standard care in a randomized trial involving patients newly admitted to the…”
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Sensible Medicine—Balancing Intervention and Inaction During the COVID-19 Pandemic by Seymour, Christopher W, McCreary, Erin K, Stegenga, Jacob

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Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016 by Rhodes, Andrew, Evans, Laura E., Alhazzani, Waleed, Levy, Mitchell M., Antonelli, Massimo, Ferrer, Ricard, Kumar, Anand, Sevransky, Jonathan E., Sprung, Charles L., Nunnally, Mark E., Rochwerg, Bram, Rubenfeld, Gordon D., Angus, Derek C., Annane, Djillali, Beale, Richard J., Bellinghan, Geoffrey J., Bernard, Gordon R., Chiche, Jean-Daniel, Coopersmith, Craig, De Backer, Daniel P., French, Craig J., Fujishima, Seitaro, Gerlach, Herwig, Hidalgo, Jorge Luis, Hollenberg, Steven M., Jones, Alan E., Karnad, Dilip R., Kleinpell, Ruth M., Koh, Younsuck, Lisboa, Thiago Costa, Machado, Flavia R., Marini, John J., Marshall, John C., Mazuski, John E., McIntyre, Lauralyn A., McLean, Anthony S., Mehta, Sangeeta, Moreno, Rui P., Myburgh, John, Navalesi, Paolo, Nishida, Osamu, Osborn, Tiffany M., Perner, Anders, Plunkett, Colleen M., Ranieri, Marco, Schorr, Christa A., Seckel, Maureen A., Seymour, Christopher W., Shieh, Lisa, Shukri, Khalid A., Simpson, Steven Q., Singer, Mervyn, Thompson, B. Taylor, Townsend, Sean R., Van der Poll, Thomas, Vincent, Jean-Louis, Wiersinga, W. Joost, Zimmerman, Janice L., Dellinger, R. Phillip

“…OBJECTIVE:To provide an update to “Surviving Sepsis Campaign Guidelines for Management of Sepsis and Septic Shock2012.” DESIGN:A consensus committee of 55…”
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Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016 by Rhodes, Andrew, Evans, Laura E., Alhazzani, Waleed, Levy, Mitchell M., Antonelli, Massimo, Ferrer, Ricard, Kumar, Anand, Sevransky, Jonathan E., Sprung, Charles L., Nunnally, Mark E., Rochwerg, Bram, Rubenfeld, Gordon D., Angus, Derek C., Annane, Djillali, Beale, Richard J., Bellinghan, Geoffrey J., Bernard, Gordon R., Chiche, Jean-Daniel, Coopersmith, Craig, De Backer, Daniel P., French, Craig J., Fujishima, Seitaro, Gerlach, Herwig, Hidalgo, Jorge Luis, Hollenberg, Steven M., Jones, Alan E., Karnad, Dilip R., Kleinpell, Ruth M., Koh, Younsuk, Lisboa, Thiago Costa, Machado, Flavia R., Marini, John J., Marshall, John C., Mazuski, John E., McIntyre, Lauralyn A., McLean, Anthony S., Mehta, Sangeeta, Moreno, Rui P., Myburgh, John, Navalesi, Paolo, Nishida, Osamu, Osborn, Tiffany M., Perner, Anders, Plunkett, Colleen M., Ranieri, Marco, Schorr, Christa A., Seckel, Maureen A., Seymour, Christopher W., Shieh, Lisa, Shukri, Khalid A., Simpson, Steven Q., Singer, Mervyn, Thompson, B. Taylor, Townsend, Sean R., Van der Poll, Thomas, Vincent, Jean-Louis, Wiersinga, W. Joost, Zimmerman, Janice L., Dellinger, R. Phillip

“…Objective To provide an update to “Surviving Sepsis Campaign Guidelines for Management of Sepsis and Septic Shock: 2012”. Design A consensus committee of 55…”
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