Evaluation of all Types of Metabolic Bariatric Surgery and its Consequences: a Systematic Review and Meta-Analysis

Background Considering conflicting results on the consequences of all types of obesity surgery, we were to summarize them via a systematic review. Methods Electronic literature search was done via scientific search engines. After the removal of duplicates and selection of articles of interest, 771 s...

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Bibliographic Details
Published in:	Obesity surgery Vol. 29; no. 2; pp. 651 - 690
Main Authors:	Khosravi-Largani, Matin, Nojomi, Marzieh, Aghili, Rokhsareh, Otaghvar, Hamidreza Alizadeh, Tanha, Kiarash, Seyedi, Seyyed Hashem Sezavar, Mottaghi, Azadeh
Format:	Journal Article
Language:	English
Published:	New York Springer US 01-02-2019 Springer Nature B.V
Subjects:	Adiponectin - blood Bariatric Surgery - methods C-Reactive Protein - analysis Gastrointestinal surgery Ghrelin - blood Glucagon-Like Peptide 1 - blood Humans Insulin - blood Insulin Resistance Intercellular Adhesion Molecule-1 - blood Interleukin-6 - blood Leptin - blood Medicine Medicine & Public Health Meta-analysis Metabolism Obesity, Morbid - blood Obesity, Morbid - surgery Peptide YY - blood Plasminogen Activator Inhibitor 1 - blood Review Article Surgery Systematic review Tumor Necrosis Factor-alpha - blood Weight control Obesity Insulin resistance Metabolic Weight Bariatric surgery
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Summary:	Background Considering conflicting results on the consequences of all types of obesity surgery, we were to summarize them via a systematic review. Methods Electronic literature search was done via scientific search engines. After the removal of duplicates and selection of articles of interest, 771 studies were included. Results Insulin resistance indicators were significantly improved after bariatric surgery. Leptin was also significantly decreased while adiponectin was significantly increased. Although the level of metabolic hormones changed after bariatric surgery, they were not statistically significant. Inflammation indicators were significantly decreased. Significant reduction was also detected in PAI-1 and sICAM-1. Conclusions Bariatric surgery is beneficial in morbidly obese patients. Although treating obesity in a surgical way may cause some complications, the weight loss is generally safe and effective.
Bibliography:	ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-1 content type line 23 ObjectType-Undefined-3
ISSN:	0960-8923 1708-0428
DOI:	10.1007/s11695-018-3550-z