Search Results - "Sexton, Katherine C"

RNA sequencing of pancreatic adenocarcinoma tumors yields novel expression patterns associated with long-term survival and reveals a role for ANGPTL4 by Kirby, Marie K., Ramaker, Ryne C., Gertz, Jason, Davis, Nicholas S., Johnston, Bobbi E., Oliver, Patsy G., Sexton, Katherine C., Greeno, Edward W., Christein, John D., Heslin, Martin J., Posey, James A., Grizzle, William E., Vickers, Selwyn M., Buchsbaum, Donald J., Cooper, Sara J., Myers, Richard M.

“…Pancreatic adenocarcinoma patients have low survival rates due to late-stage diagnosis and high rates of cancer recurrence even after surgical resection. It is…”
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How to Efficiently Obtain Human Tissues to Support Specific Biomedical Research Projects by BELL, Walter C, SEXTON, Katherine C, GRIZZLE, William E

“…The purpose of this article is to facilitate access of biomedical researchers to human tissues by describing the types of tissue resources available to…”
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Commentary on Improving Biospecimen Utilization by Classic Biobanks: Identifying Past and Minimizing Future Mistakes by Grizzle, William E, Sexton, Katherine C

“…Many classic biobanks collect more human tissues than they distribute, leading to increased inventories, unnecessary storage, increased expenses, and reduced…”
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Ensuring Effective Utilization of Biospecimens: Design, Marketing, and Other Important Approaches by Bledsoe, Marianna J, Sexton, Katherine C

“…A number of studies have shown that underutilization of biospecimens from bioresources (biobanks and biorepositories) is a significant concern. In addition,…”
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Effects of Cold Ischemia on Gene Expression: A Review and Commentary by Grizzle, William E, Otali, Dennis, Sexton, Katherine C, Atherton, Daniel S

“…Frequently investigators request that tissues be collected and processed in less than one hour following removal from a patient. Some biorepositories expend…”
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The Utilization of Biospecimens: Impact of the Choice of Biobanking Model by Grizzle, William E, Bledsoe, Marianna J, Al Diffalha, Sameer, Otali, Dennis, Sexton, Katherine C

“…The term research "biobank" is one of multiple names (e.g., bioresource, biorepository,) used to designate an entity that receives, collects, processes,…”
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The Importance of Human Tissue Bioresources in Advancing Biomedical Research by Al Diffalha, Sameer, Sexton, Katherine C, Watson, Peter H, Grizzle, William E

“…Medical research advances enabling the realization of precision medicine have relied heavily on the biospecimens provided by bioresources to identify the…”
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Factors Affecting the Use of Human Tissues in Biomedical Research: Implications in the Design and Operation of a Biorepository by Atherton, Daniel S, Sexton, Katherine C, Otali, Dennis, Bell, Walter C, Grizzle, William E

“…The availability of high-quality human tissues is necessary to advance medical research. Although there are inherent and induced limitations on the use of…”
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Lessons Learned During Three Decades of Operations of Two Prospective Bioresources by Grizzle, William E, Sexton, Katherine C, McGarvey, Diane, Menchhofen, Zachery V, LiVolsi, Virginia

“…Prospective collection is a model through which biospecimens are provided for research. Using this model, biospecimens are collected based on real-time…”
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Issues in collecting, processing and storing human tissues and associated information to support biomedical research by Grizzle, William E, Bell, Walter C, Sexton, Katherine C

“…The availability of human tissues to support biomedical research is critical to advance translational research focused on identifying and characterizing…”
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Quality management of biorepositories by Grizzle, William E, Gunter, Elaine W, Sexton, Katherine C, Bell, Walter C

“…Biomedical investigators require high quality human tissue to support their research; thus, an important aspect of the provision of tissues by biorepositories…”
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Organizational issues in providing high-quality human tissues and clinical information for the support of biomedical research by Bell, Walter C, Sexton, Katherine C, Grizzle, William E

“…Superior-quality human tissues are required to support many types of biomedical research. To be useful optimally in supporting research, not only must these…”
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The efficacy of 9-cis-retinoic acid (aliretinoin) as a chemopreventive agent for cervical dysplasia: results of a randomized double-blind clinical trial by Alvarez, Ronald D, Conner, Michael G, Weiss, Heidi, Klug, Patricia M, Niwas, Santosh, Manne, Upender, Bacus, James, Kagan, Valeriy, Sexton, Katherine C, Grubbs, Clinton J, Eltoum, Isam-Eldin, Grizzle, William E

“…9-Cis-retinoic acid (aliretinoin) is a pan-retinoid receptor agonist and has been demonstrated in preclinical models to have potent chemoprevention effects…”
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Genomic regulation of invasion by STAT3 in triple negative breast cancer by McDaniel, Joy M, Varley, Katherine E, Gertz, Jason, Savic, Daniel S, Roberts, Brian S, Bailey, Sarah K, Shevde, Lalita A, Ramaker, Ryne C, Lasseigne, Brittany N, Kirby, Marie K, Newberry, Kimberly M, Partridge, E Christopher, Jones, Angela L, Boone, Braden, Levy, Shawn E, Oliver, Patsy G, Sexton, Katherine C, Grizzle, William E, Forero, Andres, Buchsbaum, Donald J, Cooper, Sara J, Myers, Richard M

“…Breast cancer is a heterogeneous disease comprised of four molecular subtypes defined by whether the tumor-originating cells are luminal or basal epithelial…”
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Whole-exome sequencing (WES) of penile squamous cell carcinoma (PSCC) to identify multiple recurrent mutations by Naik, Gurudatta, Chen, Dongquan, Crowley, Michael, Crossman, David, Sexton, Katherine C., Grizzle, William E., Mehta, Amitkumar N., Sonpavde, Guru

“…Abstract only 484 Background: Molecular alterations and drivers of PSCC, an orphan malignancy, remain unclear. The Cancer Genome Atlas is not studying PSCC and…”
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Idiopathic pulmonary hypertension human tissue biobank by Grizzle, William E., Sexton, Katherine C., Tuder, Rubin M., McLaughlin, Valerie V., Parker, Suzanne B.

“…Idiopathic pulmonary hypertension (IPH) is characterized by elevated pulmonary arterial pressure. The pathophysiology has not been elucidated and research has…”
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The Efficacy of 9-Cis-Retinoic Acid (Aliretinoin) as a Chemopreventive Agent for Cervical Dysplasia by Ronald D. Alvarez, Michael G. Conner, Heidi Weiss, Patricia M. Klug, Santosh Niwas, Upender Manne, James Bacus, Valeriy Kagan, Katherine C. Sexton, Clinton J. Grubbs, Isam-Eldin Eltoum, William E. Grizzle

“…9- Cis- retinoic acid (aliretinoin) is a pan-retinoid receptor agonist and has been demonstrated in preclinical models to have potent chemoprevention effects…”
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The efficacy of 9-cis-retinoic acid (aliretinoin) as a chemopreventive agent for cervical dysplasia: Results of a randomized double-blind clinical trials by ALVAREZ, Ronald D, CONNER, Michael G, ELTOUM, Isam-Eldin, GRIZZLE, William E, WEISS, Heidi, KLUG, Patricia M, NIWAS, Santosh, MANNE, Upender, BACUS, James, KAGAN, Valeriy, SEXTON, Katherine C, GRUBBS, Clinton J

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