Search Results - "Seward, Matthew E"

Amyloid-β signals through tau to drive ectopic neuronal cell cycle re-entry in Alzheimer's disease by Seward, Matthew E, Swanson, Eric, Norambuena, Andrés, Reimann, Anja, Cochran, J Nicholas, Li, Rong, Roberson, Erik D, Bloom, George S

“…Normally post-mitotic neurons that aberrantly re-enter the cell cycle without dividing account for a substantial fraction of the neurons that die in…”
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Alzheimer disease: A tale of two prions by Nussbaum, Justin M., Seward, Matthew E., Bloom, George S.

“…Alzheimer disease (AD) has traditionally been thought to involve the misfolding and aggregation of two different factors that contribute in parallel to…”
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Laminin activates CaMK-II to stabilize nascent embryonic axons by Easley, Charles A., Faison, Milton O., Kirsch, Therese L., Lee, Jocelyn A., Seward, Matthew E., Tombes, Robert M.

“…In neurons, the interaction of laminin with its receptor, β1 integrin, is accompanied by an increase in cytosolic Ca 2+. Neuronal behavior is influenced by…”
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Intraneuronal Tau Misfolding Induced by Extracellular Amyloid-β Oligomers by Rudenko, Lauren K, Wallrabe, Horst, Periasamy, Ammasi, Siller, Karsten H, Svindrych, Zdenek, Seward, Matthew E, Best, Merci N, Bloom, George S

“…Abnormal folding and aggregation of the microtubule-associated protein, tau, is a hallmark of several neurodegenerative disorders, including Alzheimer's…”
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Flightless-I, a gelsolin family member and transcriptional regulator, preferentially binds directly to activated cytosolic CaMK-II by Seward, Matthew E., Easley, Charles A., McLeod, Jamie J., Myers, Alexandra L., Tombes, Robert M.

“…In order to evaluate links between Ca2+/calmodulin (CaM)-dependent protein kinase type II (CaMK-II) and cell cycle progression, CaMK-II binding partners were…”
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Alzheimer disease: A tale of two prions by Justin M. Nussbaum, Matthew E. Seward, George S. Bloom

“…Alzheimer disease (AD) has traditionally been thought to involve the misfolding and aggregation of two different factors that contribute in parallel to…”
Get full text