Search Results - "Severson, David T"
-
1
Mesothelioma: Scientific clues for prevention, diagnosis, and therapy
Published in CA: a cancer journal for clinicians (01-09-2019)“…Mesothelioma affects mostly older individuals who have been occupationally exposed to asbestos. The global mesothelioma incidence and mortality rates are…”
Get full text
Journal Article -
2
A Code for RanGDP Binding in Ankyrin Repeats Defines a Nuclear Import Pathway
Published in Cell (22-05-2014)“…Regulation of nuclear import is fundamental to eukaryotic biology. The majority of nuclear import pathways are mediated by importin-cargo interactions. Yet not…”
Get full text
Journal Article -
3
STAT1 -induced ASPP2 transcription identifies a link between neuroinflammation, cell polarity, and tumor suppression
Published in Proceedings of the National Academy of Sciences - PNAS (08-07-2014)“…Inflammation and loss of cell polarity play pivotal roles in neurodegeneration and cancer. A central question in both diseases is how the loss of cell polarity…”
Get full text
Journal Article -
4
Mesothelioma in the age of “Omics”: Before and after The Cancer Genome Atlas
Published in The Journal of thoracic and cardiovascular surgery (01-10-2020)“…Malignant pleural mesothelioma (MPM) is a highly fatal cancer of the pleura that has been defeating standard and investigational therapies since its first…”
Get full text
Journal Article -
5
Large‐scale analysis of BAP1 expression reveals novel associations with clinical and molecular features of malignant pleural mesothelioma
Published in The Journal of pathology (01-01-2021)“…BRCA1‐associated protein‐1 (BAP1) expression is commonly lost in several tumors including malignant pleural mesothelioma (MPM). Presence or absence of…”
Get full text
Journal Article -
6
Association of RERG Expression with Female Survival Advantage in Malignant Pleural Mesothelioma
Published in Cancers (02-02-2021)“…Sex differences in incidence, prognosis, and treatment response have been described for many cancers. In malignant pleural mesothelioma (MPM), a lethal disease…”
Get full text
Journal Article -
7
Abstract 95: Uncommitted cells and phenotypic plasticity elucidate the complexity of the epithelial-mesenchymal molecular gradient of pleural mesothelioma
Published in Cancer research (Chicago, Ill.) (04-04-2023)“…Abstract Pleural mesothelioma (PM) comprises three major histologic types: epithelioid, sarcomatoid, and a mixture of the two types termed biphasic. We and…”
Get full text
Journal Article -
8
A study of the cellular and environmental context of Barrett's esophagus
Published 01-01-2017“…Barrett's esophagus is a pre-malignant lesion leading to esophageal adeno-carcinoma, where presence of Barrett's carries a seven fold increase in risk of…”
Get full text
Dissertation