Search Results - "Severson, David T"

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    A Code for RanGDP Binding in Ankyrin Repeats Defines a Nuclear Import Pathway by Lu, Min, Zak, Jaroslav, Chen, Shuo, Sanchez-Pulido, Luis, Severson, David T., Endicott, Jane, Ponting, Chris P., Schofield, Christopher J., Lu, Xin

    Published in Cell (22-05-2014)
    “…Regulation of nuclear import is fundamental to eukaryotic biology. The majority of nuclear import pathways are mediated by importin-cargo interactions. Yet not…”
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    Journal Article
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    STAT1 -induced ASPP2 transcription identifies a link between neuroinflammation, cell polarity, and tumor suppression by Turnquist, Casmir, Wang, Yihua, Severson, David T., Zhong, Shan, Sun, Bin, Ma, Jingyi, Constaninescu, Stefan N., Ansorge, Olaf, Stolp, Helen B., Molnár, Zoltán, Szele, Francis G., Lu, Xin

    “…Inflammation and loss of cell polarity play pivotal roles in neurodegeneration and cancer. A central question in both diseases is how the loss of cell polarity…”
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    Journal Article
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    Mesothelioma in the age of “Omics”: Before and after The Cancer Genome Atlas by Severson, David T., De Rienzo, Assunta, Bueno, Raphael

    “…Malignant pleural mesothelioma (MPM) is a highly fatal cancer of the pleura that has been defeating standard and investigational therapies since its first…”
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    Journal Article
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    Association of RERG Expression with Female Survival Advantage in Malignant Pleural Mesothelioma by De Rienzo, Assunta, Coleman, Melissa H, Yeap, Beow Y, Severson, David T, Wadowski, Benjamin, Gustafson, Corinne E, Jensen, Roderick V, Chirieac, Lucian R, Richards, William G, Bueno, Raphael

    Published in Cancers (02-02-2021)
    “…Sex differences in incidence, prognosis, and treatment response have been described for many cancers. In malignant pleural mesothelioma (MPM), a lethal disease…”
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    Journal Article
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    A study of the cellular and environmental context of Barrett's esophagus by Severson, David T

    Published 01-01-2017
    “…Barrett's esophagus is a pre-malignant lesion leading to esophageal adeno-carcinoma, where presence of Barrett's carries a seven fold increase in risk of…”
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    Dissertation