Search Results - "Severi, Kristen E."
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Neural Control and Modulation of Swimming Speed in the Larval Zebrafish
Published in Neuron (Cambridge, Mass.) (06-08-2014)“…Vertebrate locomotion at different speeds is driven by descending excitatory connections to central pattern generators in the spinal cord. To investigate how…”
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Optimization of a Neurotoxin to Investigate the Contribution of Excitatory Interneurons to Speed Modulation In Vivo
Published in Current biology (12-09-2016)“…Precise control of speed during locomotion is essential for adaptation of behavior in different environmental contexts [1–4]. A central question in locomotion…”
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Optogenetics in a transparent animal: circuit function in the larval zebrafish
Published in Current opinion in neurobiology (01-02-2013)“…Highlights ► The transparency of the larval zebrafish allows for non-invasive optogenetic detection and modulation of neural activity throughout the brain. ►…”
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Investigation of hindbrain activity during active locomotion reveals inhibitory neurons involved in sensorimotor processing
Published in Scientific reports (11-09-2018)“…Locomotion in vertebrates relies on motor circuits in the spinal cord receiving inputs from the hindbrain to execute motor commands while dynamically…”
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Genetically encoded calcium indicators for multi-color neural activity imaging and combination with optogenetics
Published in Frontiers in molecular neuroscience (01-01-2013)“…Genetically encoded calcium indicators (GECIs) are powerful tools for systems neuroscience. Here we describe red, single-wavelength GECIs, "RCaMPs," engineered…”
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Control of visually guided behavior by distinct populations of spinal projection neurons
Published in Nature neuroscience (01-03-2008)“…A basic question in the field of motor control is how different actions are represented by activity in spinal projection neurons. We used a new behavioral…”
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ZebraZoom: an automated program for high-throughput behavioral analysis and categorization
Published in Frontiers in neural circuits (2013)“…The zebrafish larva stands out as an emergent model organism for translational studies involving gene or drug screening thanks to its size, genetics, and…”
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Evolutionary and homeostatic changes in morphology of visual dendrites of Mauthner cells in Astyanax blind cavefish
Published in Journal of comparative neurology (1911) (01-06-2021)“…Mauthner cells are the largest neurons in the hindbrain of teleost fish and most amphibians. Each cell has two major dendrites thought to receive segregated…”
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Motor behavior: A feedforward circuit for zebrafish escape
Published in Current biology (09-08-2021)“…A recent study of motor control in zebrafish demonstrates the critical role of an excitatory neural relay network in the transformation of a unilateral turn…”
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Resilience of neural networks for locomotion
Published in The Journal of physiology (01-08-2021)“…Locomotion is an essential behaviour for the survival of all animals. The neural circuitry underlying locomotion is therefore highly robust to a wide variety…”
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Larval Zebrafish Exhibit Collective Circulation in Confined Spaces
Published in Frontiers in physics (24-09-2021)“…Collective behavior may be elicited or can spontaneously emerge by a combination of interactions with the physical environment and conspecifics moving within…”
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Cellular-level understanding of supraspinal control: what can be learned from zebrafish?
Published in Current opinion in physiology (01-04-2019)“…•Regions such as the MLR were discovered using electrical stimulation.•Genetic and optogenetic techniques are now revealing functional heterogeneity within…”
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Expansion microscopy reveals neural circuit organization in genetic animal models
Published 10-11-2024“…Expansion Microscopy is a super-resolution technique in which physically enlarging samples in an isotropic manner increases inter-molecular distances such that…”
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