Search Results - "Sevenich, L"

Cell type-dependent pathogenic functions of overexpressed human cathepsin B in murine breast cancer progression by Bengsch, F, Buck, A, Günther, S C, Seiz, J R, Tacke, M, Pfeifer, D, von Elverfeldt, D, Sevenich, L, Hillebrand, L E, Kern, U, Sameni, M, Peters, C, Sloane, B F, Reinheckel, T

“…The cysteine protease cathepsin B (CTSB) is frequently overexpressed in human breast cancer and correlated with a poor prognosis. Genetic deficiency or…”
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AAV-mediated gene transfer of a checkpoint inhibitor in combination with HER2-targeted CAR-NK cells as experimental therapy for glioblastoma by Strecker, M.I., Wlotzka, K., Strassheimer, F., Roller, B., Ludmirski, G., König, S., Röder, J., Opitz, C., Alekseeva, T., Reul, J., Sevenich, L., Tonn, T., Wels, W.S., Steinbach, J.P., Buchholz, C.J., Burger, M.C.

“…Glioblastoma (GB) is the most common primary brain tumor, which is characterized by low immunogenicity of tumor cells and prevalent immunosuppression in the…”
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Transgenic expression of human cathepsin B promotes progression and metastasis of polyoma-middle-T-induced breast cancer in mice by Sevenich, L, Werner, F, Gajda, M, Schurigt, U, Sieber, C, Müller, S, Follo, M, Peters, C, Reinheckel, T

“…Elevated expression of the cysteine protease cathepsin B (CTSB) has been correlated with a poor prognosis for cancer patients. In order to model high CTSB…”
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Reduced tumour cell proliferation and delayed development of high-grade mammary carcinomas in cathepsin B-deficient mice by Vasiljeva, O, Korovin, M, Gajda, M, Brodoefel, H, Bojic̆, L, Krüger, A, Schurigt, U, Sevenich, L, Turk, B, Peters, C, Reinheckel, T

“…Expression levels of the papain-like cysteine protease cathepsin B (Ctsb) have been positively correlated with mammary tumour progression and metastasis;…”
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Analysis of tumour- and stroma-supplied proteolytic networks reveals a brain-metastasis-promoting role for cathepsin S by Sevenich, Lisa, Bowman, Robert L., Mason, Steven D., Quail, Daniela F., Rapaport, Franck, Elie, Benelita T., Brogi, Edi, Brastianos, Priscilla K., Hahn, William C., Holsinger, Leslie J., Massagué, Joan, Leslie, Christina S., Joyce, Johanna A.

“…Metastasis remains the most common cause of death in most cancers, with limited therapies for combating disseminated disease. While the primary tumour…”
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P06.06.B PD-1 CHECKPOINT INHIBITION IN CONJUNCTION WITH NK-92/5.28.Z CELLS IS EFFECTIVE IN AN ADVANCED-STAGE GLIOBLASTOMA MOUSE MODEL AND INDUCES A CD4-ENRICHED T CELL RESPONSE by Strassheimer, F, Roller, B, Mildenberger, I C, Macas, J, Alekseeva, T, Tonn, T, Sevenich, L, Reiss, Y, Weber, K J, Plate, K H, Weigert, A, Wels, W S, Steinbach, J P, Burger, M C

“…Abstract INTRODUCTION Checkpoint inhibition in combination with adoptive cell therapy holds promise for cancer immunotherapy, and encouraging treatment…”
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OS12.6.A Combination therapy of CAR-NK-cells and anti-PD-1 results in high efficacy against advanced-stage glioblastoma in a syngeneic mouse model and induces protective anti-tumor immunity in vivo by Strassheimer, F, Strecker, M I, Alekseeva, T, Macas, J, Demes, M C, Mildenberger, I C, Tonn, T, Wild, P J, Sevenich, L, Reiss, Y, Harter, P N, Plate, K H, Wels, W S, Steinbach, J P, Burger, M C

“…Abstract INTRODUCTION Checkpoint inhibitors as well as adoptive cell therapy hold promise for cancer therapy and encouraging treatment responses have already…”
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P06.12 Combination therapy of CAR-NK-cells and anti-PD-1 antibody results in high efficacy against advanced-stage glioblastoma in a syngeneic mouse model and induces protective anti-tumor immunity in vivo by Strassheimer, F, Strecker, MI, Alekseeva, T, Macas, J, Demes, M C, Mildenberger, I C, Tonn, T, Wild, P J, Sevenich, L, Reiss, Y, Harter, P N, Plate, KH, Wels, W S, Steinbach, J P, Burger, M C

“…BackgroundCheckpoint inhibitors as well as adoptive cell therapy hold great promise for cancer therapy and encouraging treatment responses have already been…”
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Localization of cathepsin x in the mouse retina by BERGER, ST, STAHL, A, GROSS, NJ, SEVENICH, L, MARTIN, G, REINHECKEL, T, AGOSTINI, HT

“…Purpose Cathepsin X is a recently identified member of the papain‐like cysteine protease family that is expressed by many cell types. The in vivo functions of…”
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Evidence for an acoustical pathway to the inner ear through the lower jaw for an echolocating dolphin ( Tursiops truncatus ) by Brill, Randall L., Sevenich, Martha L., Sullivan, Timothy J., Sustman, Janet D., Witt, Ronald E.

“…A dolphin (Tursiops truncatus) was conditioned to perform a discrimination task, by means of echolocation, in a “Go/No-go” paradigm while stationed in an…”
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