Search Results - "Sevastre, Ani Simona"
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Updated Insights on EGFR Signaling Pathways in Glioma
Published in International journal of molecular sciences (08-01-2021)“…Nowadays, due to recent advances in molecular biology, the pathogenesis of glioblastoma is better understood. For the newly diagnosed, the current standard of…”
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An Overview of EGFR Mechanisms and Their Implications in Targeted Therapies for Glioblastoma
Published in International journal of molecular sciences (01-07-2023)“…Despite all of the progress in understanding its molecular biology and pathogenesis, glioblastoma (GBM) is one of the most aggressive types of cancers, and…”
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Glioblastoma Stem Cells-Useful Tools in the Battle against Cancer
Published in International journal of molecular sciences (21-04-2022)“…Glioblastoma stem cells (GSCs) are cells with a self-renewal ability and capacity to initiate tumors upon serial transplantation that have been linked to tumor…”
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Intracellular Pathways and Mechanisms of Colored Secondary Metabolites in Cancer Therapy
Published in International journal of molecular sciences (01-09-2022)“…Despite the great advancements made in cancer treatment, there are still many unsatisfied aspects, such as the wide palette of side effects and the drug…”
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ELTD1—An Emerging Silent Actor in Cancer Drama Play
Published in International journal of molecular sciences (13-05-2021)“…The epidermal growth factor, latrophilin, and seven transmembrane domain–containing protein 1 (ELTD1), is a member of the G–protein coupled receptors (GPCRs)…”
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Receptor tyrosine kinase targeting in glioblastoma: performance, limitations and future approaches
Published in Contemporary oncology (Poznan, Poland) (01-01-2020)“…From all central nervous system tumors, gliomas are the most common. Nowadays, researchers are looking for more efficient treatments for these tumors, as well…”
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Platelet-Derived Growth Factor Receptor and Ionizing Radiation in High Grade Glioma Cell Lines
Published in International journal of molecular sciences (20-09-2019)“…Treatment of high grade gliomas (HGGs) has remained elusive due to their high heterogeneity and aggressiveness. Surgery followed by radiotherapy represents the…”
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The effect of temozolomide in combination with doxorubicin in glioblastoma cells in vitro
Published in Journal of immunoassay & immunochemistry (01-11-2020)“…Prior to 2000, the DNA alkylating agents nitrosoureas were used as standard treatment of glioblastoma. Current treatments for glioblastoma patients consist of…”
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Evaluation of Natural Extracts in Animal Models of Pain and Inflammation for a Potential Therapy of Hemorrhoidal Disease
Published in Scientia pharmaceutica (01-06-2019)“…The aim of this work was to assess the analgesic effect of three Vitis vinifera L. leaf extracts and the anti-inflammatory effect of three gels obtained from…”
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Evaluation of cytotoxicity and apoptotic effects of Catharanthus roseus on the human lung cancer cell lines CaLu-6
Published in Revista română de medicină de laborator (01-04-2024)“…Abstract Background Lung cancer is ranked as the fourth global important cause of cancer related deaths. Despite remarkable advances in drug design, the…”
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The effect of Azo-dyes on glioblastoma cells in vitro
Published in Saudi journal of biological sciences (01-03-2023)“…Despite the multidisciplinary standard treatment of glioblastoma (GB) consisting of maximal surgical resection, followed by radiotherapy (RT) plus concomitant…”
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Glioblastoma pharmacotherapy: A multifaceted perspective of conventional and emerging treatments (Review)
Published in Experimental and therapeutic medicine (01-12-2021)“…Due to its localisation, rapid onset, high relapse rate and resistance to most currently available treatment methods, glioblastoma multiforme (GBM) is…”
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The Potential of Helianthin Loaded Into Magnetic Nanoparticles to Induce Cytotoxicity in Glioblastoma Cells
Published in Current health sciences journal (01-07-2021)“…The central nervous system tumors are the most common solid tumors in adults.. Unlike other types of cancers, brain cancer is much difficult to treat because…”
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In vitro evaluation of Axitinib and Sorafenib treatment in glioblastoma cell viability and morphology
Published in Romanian journal of morphology and embryology (01-04-2023)“…The formation, proliferation, and evolution of glioblastoma (GB) are significantly influenced by pathological angiogenesis. This is supported by several growth…”
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