Search Results - "Sevastik, Robin"

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  1. 1

    Cofactor mobility determines reaction outcome in the IMPDH and GMPR (β-α)8 barrel enzymes by Patton, Gregory C, Stenmark, Pål, Gollapalli, Deviprasad R, Sevastik, Robin, Kursula, Petri, Flodin, Susanne, Schuler, Herwig, Swales, Colin T, Eklund, Hans, Himo, Fahmi, Nordlund, Pär, Hedstrom, Lizbeth

    Published in Nature chemical biology (30-10-2011)
    “…IMPDH and GMPR have similar active sites, but their reactions cause opposite effects on the guanine nucleotide pool. Biochemical and crystallographic evidence…”
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    Journal Article
  2. 2

    Renal volume and function in school-age children born preterm or small for gestational age by Rakow, Alexander, Johansson, Stefan, Legnevall, Lena, Sevastik, Robin, Celsi, Gianni, Norman, Mikael, Vanpée, Mireille

    Published in Pediatric nephrology (Berlin, West) (01-08-2008)
    “…Impaired renal development during foetal life is a proposed mechanism for adult hypertension in people born small. Whether preterm birth contributes to such…”
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    Journal Article
  3. 3

    Quantum chemical modeling of enzymatic reactions: The case of 4-oxalocrotonate tautomerase by Sevastik, Robin, Himo, Fahmi

    Published in Bioorganic chemistry (01-12-2007)
    “…The reaction mechanism of 4-oxalocrotonate tautomerase (4-OT) is studied using the density functional theory method B3LYP. This enzyme catalyzes the…”
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    Journal Article
  4. 4

    Reaction Mechanism of cis-3-Chloroacrylic Acid Dehalogenase: A Theoretical Study by Sevastik, Robin, Whitman, Christian P, Himo, Fahmi

    Published in Biochemistry (Easton) (13-10-2009)
    “…The reaction mechanism of cis-3-chloroacrylic acid dehalogenase (cis-CaaD) is studied using the B3LYP density functional theory method. This enzyme catalyzes…”
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    Journal Article
  5. 5

    Cofactor mobility determines reaction outcome in the IMPDH and GMPR (beta-alpha)(8) barrel enzymes by Patton, Gregory C., Stenmark, Pål, Gollapalli, Deviprasad R., Sevastik, Robin, Kursula, Petri, Flodin, Susanne, Schuler, Herwig, Swales, Colin T., Eklund, Hans, Himo, Fahmi, Nordlund, Par, Hedstrom, Lizbeth

    Published in Chemistry & biology (2011)
    “…Inosine monophosphate dehydrogenase (IMPDH) and guanosine monophosphate reductase (GMPR) belong to the same structural family, share a common set of catalytic…”
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    Journal Article