Search Results - "Sevastik, Robin"
-
1
Cofactor mobility determines reaction outcome in the IMPDH and GMPR (β-α)8 barrel enzymes
Published in Nature chemical biology (30-10-2011)“…IMPDH and GMPR have similar active sites, but their reactions cause opposite effects on the guanine nucleotide pool. Biochemical and crystallographic evidence…”
Get full text
Journal Article -
2
Renal volume and function in school-age children born preterm or small for gestational age
Published in Pediatric nephrology (Berlin, West) (01-08-2008)“…Impaired renal development during foetal life is a proposed mechanism for adult hypertension in people born small. Whether preterm birth contributes to such…”
Get full text
Journal Article -
3
Quantum chemical modeling of enzymatic reactions: The case of 4-oxalocrotonate tautomerase
Published in Bioorganic chemistry (01-12-2007)“…The reaction mechanism of 4-oxalocrotonate tautomerase (4-OT) is studied using the density functional theory method B3LYP. This enzyme catalyzes the…”
Get full text
Journal Article -
4
Reaction Mechanism of cis-3-Chloroacrylic Acid Dehalogenase: A Theoretical Study
Published in Biochemistry (Easton) (13-10-2009)“…The reaction mechanism of cis-3-chloroacrylic acid dehalogenase (cis-CaaD) is studied using the B3LYP density functional theory method. This enzyme catalyzes…”
Get full text
Journal Article -
5
Cofactor mobility determines reaction outcome in the IMPDH and GMPR (beta-alpha)(8) barrel enzymes
Published in Chemistry & biology (2011)“…Inosine monophosphate dehydrogenase (IMPDH) and guanosine monophosphate reductase (GMPR) belong to the same structural family, share a common set of catalytic…”
Get full text
Journal Article