Search Results - "Seuwen, K."

CNS distribution, signalling properties and central effects of G-protein coupled receptor 4 by Hosford, P.S., Mosienko, V., Kishi, K., Jurisic, G., Seuwen, K., Kinzel, B., Ludwig, M.G., Wells, J.A., Christie, I.N., Koolen, L., Abdala, A.P., Liu, B.H., Gourine, A.V., Teschemacher, A.G., Kasparov, S.

“…Information on the distribution and biology of the G-protein coupled receptor 4 (GPR4) in the brain is limited. It is currently thought that GPR4 couples to Gs…”
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Enhanced marrow adipogenesis and bone resorption in estrogen-deprived rats treated with the PPARgamma agonist BRL49653 (rosiglitazone) by Sottile, V, Seuwen, K, Kneissel, M

“…Thiazolidinediones are insulin-sensitizing agents and in clinical use for the treatment of type II diabetes. Under specific experimental conditions, these…”
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Stem cell characteristics of human trabecular bone-derived cells by Sottile, V, Halleux, C, Bassilana, F, Keller, H, Seuwen, K

“…Human trabecular bone-derived cells (HTBs) have been used for many years as osteoblast progenitors. In this study we tested whether HTBs have stem cell…”
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Bone morphogenetic protein 2 induces placental growth factor in mesenchymal stem cells by Marrony, S, Bassilana, F, Seuwen, K, Keller, H

“…Bone-forming osteoblasts differentiate from pluripotent mesenchymal stem cells (MSCs) in a multistage process that can be modeled in vitro using MSCs isolated…”
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Characterisation of human recombinant somatostatin receptors. 1. Radioligand binding studies by Siehler, S, Seuwen, K, Hoyer, D

“…Human somatostatin receptor subtypes 1-5 (sst1-5) were characterised using the agonist radioligands [125I]LTT-SRIF28, [125I][Tyr10]CST14, [125I]CGP 23996 and…”
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[125I][Tyr3]octreotide labels human somatostatin sst2 and sst5 receptors by SIEHLER, S, SEUWEN, K, HOYER, D

“…Human somatostatin (somatotropin release inhibiting factor = SRIF) receptor subtypes sst2 and sst5 were stably expressed in Chinese hamster lung fibroblast…”
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Coordinate, biphasic activation of p44 mitogen-activated protein kinase and S6 kinase by growth factors in hamster fibroblasts. Evidence for thrombin-induced signals different from phosphoinositide turnover and adenylylcyclase inhibition by KAHAN, C, SEUWEN, K, MELOCHE, S, POUYSSEGUR, J

“…In CCL39 cells transfected with m1-muscarinic receptors, carbachol stimulates phosphoinositide turnover and early events associated with mitogenesis as…”
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Deregulation of hamster fibroblast proliferation by mutated ras oncogenes is not mediated by constitutive activation of phosphoinositide‐specific phospholipase C by Seuwen, K., Lagarde, A., Pouysségur, J.

“…Stable expression of high levels of activated forms of Haras (T24) or v‐Ki‐ras by transfection of Chinese hamster lung fibroblasts (CCL39) yielded cells highly…”
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Human tryptase as a potent, cell-specific mitogen: role of signaling pathways in synergistic responses by Hartmann, T, Ruoss, S J, Raymond, W W, Seuwen, K, Caughey, G H

“…Mast cells are hypothesized to participate in processes leading to tissue fibrosis in human lung and skin. To explore the possible involvement of mast cell…”
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Stimulation of phosphatidylcholine breakdown by thrombin and carbachol but not by tyrosine kinase receptor ligands in cells transfected with M1 muscarinic receptors. Rapid desensitization of phosphocholine-specific (PC) phospholipase D but sustained activity of PC-phospholipase C by McKenzie, FR, Seuwen, K, Pouyssegur, J

“…In order to evaluate the possible contribution of phospholipase D (PLD) stimulation to the mitogenic response, a screening of a variety of different compounds,…”
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Proton-sensing G-protein-coupled receptors by Seuwen, Klaus, Ludwig, Marie-Gabrielle, Vanek, Miroslava, Guerini, Danilo, Gasser, Jürg A, Jones, Carol E, Junker, Uwe, Hofstetter, Hans, Wolf, Romain M

“…Blood pH is maintained in a narrow range around pH 7.4 mainly through regulation of respiration and renal acid extrusion. The molecular mechanisms involved in…”
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C67 ACUTE LUNG INJURY: Peptide-Based Activation Of Gpr116 On Alveolar Epithelial Cells Induces G Protein-Coupled Responses And Modulates Alveolar Surfactant Pool Sizes In Vivo by Bridges, J, Filuta, A, Brown, K, Arora, K, Naren, A, Ludwig, M-G, Seuwen, K, Jaros, J, Miller, W

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Bone morphogenetic protein-2 stimulates adipogenic differentiation of mesenchymal precursor cells in synergy with BRL 49653 (rosiglitazone) by Sottile, Virginie, Seuwen, Klaus

“…Bone morphogenetic proteins (BMPs) were discovered as potent bone-inducing molecules. Their effect on adipogenic differentiation is not well understood, both…”
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P072 The role of the rs8005161 polymorphism on pH-sensing G protein-coupled receptor GPR65 (TDAG8) signalling in intestinal inflammation by Tcymbarevich, I., Obialo, N., Cosin-Roger, J., Seuwen, K., Rogler, G., Misselwitz, B., de Vallière, C.

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DOP24 Intestinal acidification sensed by pH-sensing receptor GPR4 contributes to fibrogenesis by Weder, B, Van Haaften, W T, Baebler, K, Rogler, G, Dijkstra, G, Imenez Silva, P H, Wang, Y, De Vallière, C, Wagner, C, Frey-Wagner, I, Seuwen, K, Ruiz, P, Hausmann, M

“…Abstract Background During active inflammation, intraluminal intestinal pH is decreased in patients with inflammatory bowel disease (IBD). Acidic pH may play a…”
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Homology Modeling of the Transmembrane Domain of the Human Calcium Sensing Receptor and Localization of an Allosteric Binding Site by Miedlich, Susanne U., Gama, Lucio, Seuwen, Klaus, Wolf, Romain M., Breitwieser, Gerda E.

“…A homology model for the human calcium sensing receptor (hCaR) transmembrane domain utilizing bovine rhodopsin (bRho) structural information was derived and…”
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P017 OGR1 (GPR68) expression is increased in intestinal inflammation and correlates with disease activity in patients with IBD by Cosin-Roger, J., Bengs, S., Lang, S., Turina, M., Rickenbacher, A., Seuwen, K., Ruiz, P.A., Misselwitz, B., Rogler, G., de Vallière, C.

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P052 The role of TDAG8 in intestinal inflammation by Tcymbarevich, I., de Vallière, C., Spalinger, M., Cosin-Roger, J., Atrott, K., Richards, S., Seuwen, K., Frey-Wagner, I., Rogler, G.

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Strong and persistent activation of inositol lipid breakdown induces early mitogenic events but not Go to S phase progression in hamster fibroblasts. Comparison of thrombin and carbachol action in cells expressing M1 muscarinic acetylcholine receptors by Seuwen, K., Kahan, C., Hartmann, T., Pouyssegur, J.

“…In order to evaluate the role of phosphoinositide turnover in growth factor action, we expressed human M1 muscarinic acetylcholine (Hm1) receptors in Chinese…”
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Signal transduction in hamster fibroblasts overexpressing the human EGF receptor by L'Allemain, G, Seuwen, K, Velu, T, Pouyssegur, J

“…Human EGF receptors (HERs) were expressed in CCL39 hamster fibroblasts, a cell line responding only weakly to EGF despite the presence of 10-20,000 EGF…”
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