Search Results - "Seung-ki Kwok"

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    Interleukin-10 produced by myeloid-derived suppressor cells is critical for the induction of Tregs and attenuation of rheumatoid inflammation in mice by Park, Min-Jung, Lee, Sung-Hee, Kim, Eun-Kyung, Lee, Eun-Jung, Baek, Jin-Ah, Park, Sung-Hwan, Kwok, Seung-Ki, Cho, Mi-La

    Published in Scientific reports (28-02-2018)
    “…Myeloid-derived suppressor cells (MDSCs) are heterogenous populations of immature myeloid progenitor cells with immunoregulatory function. MDSCs play critical…”
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    Journal Article
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    Recent Advances in Our Understanding of the Link between the Intestinal Microbiota and Systemic Lupus Erythematosus by Kim, Ji-Won, Kwok, Seung-Ki, Choe, Jung-Yoon, Park, Sung-Hwan

    “…Systemic lupus erythematosus (SLE) is an autoimmune disease featuring enhanced expression of type I interferon (IFN) and autoantibody production triggering…”
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    Journal Article
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    Myeloid‐Derived Suppressor Cells Induce the Expansion of Regulatory B Cells and Ameliorate Autoimmunity in the Sanroque Mouse Model of Systemic Lupus Erythematosus by Park, Min‐Jung, Lee, Sung‐Hee, Kim, Eun‐Kyung, Lee, Eun‐Jung, Park, Sung‐Hwan, Kwok, SeungKi, Cho, Mi‐La

    Published in Arthritis & rheumatology (Hoboken, N.J.) (01-11-2016)
    “…Objective This study was undertaken to assess the effect of myeloid‐derived suppressor cells (MDSCs) on various B cell subsets, including regulatory B cells,…”
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    Journal Article
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    JAK-1 Inhibition Suppresses Interferon-Induced BAFF Production in Human Salivary Gland: Potential Therapeutic Strategy for Primary Sjögren's Syndrome by Lee, Jaeseon, Lee, Jennifer, Kwok, Seung-Ki, Baek, SeungYe, Jang, Se Gwang, Hong, Seung-Min, Min, Jae-Woong, Choi, Sun Shim, Lee, Juhyun, Cho, Mi-La, Park, Sung-Hwan

    Published in Arthritis & rheumatology (Hoboken, N.J.) (01-12-2018)
    “…To examine whether a JAK inhibitor regulates functional responses of human salivary gland epithelial cells (SGECs) and disease parameters in an animal model of…”
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    Journal Article
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    Mesenchymal Stem/Stromal Cell-Based Therapies in Systemic Rheumatic Disease: From Challenges to New Approaches for Overcoming Restrictions by Lee, Bong-Woo, Kwok, Seung-Ki

    “…Systemic rheumatic diseases, such as rheumatoid arthritis, systemic lupus erythematosus, and systemic sclerosis, are chronic autoimmune diseases affecting…”
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    Journal Article
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    Short-chain fatty acid butyrate induces IL-10-producing B cells by regulating circadian-clock-related genes to ameliorate Sjögren's syndrome by Kim, Da Som, Woo, Jin Seok, Min, Hong-Ki, Choi, Jeong-Won, Moon, Jeong Hyeon, Park, Min-Jung, Kwok, Seung-Ki, Park, Sung-Hwan, Cho, Mi-La

    Published in Journal of autoimmunity (01-05-2021)
    “…Sjögren's syndrome (SS) is an autoimmune disease caused by inflammation of the exocrine gland. The pathological hallmark of SS is the infiltration of…”
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    Journal Article
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    Metformin Augments Anti-Inflammatory and Chondroprotective Properties of Mesenchymal Stem Cells in Experimental Osteoarthritis by Park, Min-Jung, Moon, Su-Jin, Baek, Jin-Ah, Lee, Eun-Jung, Jung, Kyung-Ah, Kim, Eun-Kyung, Kim, Da-Som, Lee, Jung-Ho, Kwok, Seung-Ki, Min, Jun-Ki, Kim, Seok Jung, Park, Sung-Hwan, Cho, Mi-La

    Published in The Journal of immunology (1950) (01-07-2019)
    “…Mesenchymal stem cells (MSCs) can protect against cartilage breakdown in osteoarthritis (OA) via their immunomodulatory capacities. However, the optimization…”
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    Journal Article
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    Predictors for future development of systemic lupus erythematosus in Korean Sjögren’s syndrome patients by Lee, Bong-Woo, Kwon, Eui-Jong, Park, Youngjae, Lee, Jennifer Jooha, Ju, Ji Hyeon, Park, Sung-Hwan, Kwok, Seung-Ki

    Published in Lupus (01-10-2023)
    “…Objective This study determined the impact of demographic factors, clinical manifestations, disease activity, and serological tests at baseline on future SLE…”
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    Journal Article
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    Longitudinal analysis of symptom-based clustering in patients with primary Sjogren's syndrome: a prospective cohort study with a 5-year follow-up period by Lee, Jennifer Jooha, Park, Young Jae, Park, Misun, Yim, Hyeon Woo, Park, Sung Hwan, Kwok, Seung-Ki

    Published in Journal of translational medicine (19-09-2021)
    “…Sjogren's syndrome (SS) is a heterogenous disease with various phenotypes. We aimed to provide a relevant subclassification based on symptom-based clustering…”
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    Journal Article
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    Alcohol consumption as a predictor of the progression of spinal structural damage in axial spondyloarthritis: data from the Catholic Axial Spondyloarthritis COhort (CASCO) by Min, Hong Ki, Lee, Jennifer, Ju, Ji Hyeon, Park, Sung-Hwan, Kwok, Seung-Ki

    Published in Arthritis research & therapy (14-08-2019)
    “…The purpose of the present study was to demonstrate whether alcohol consumption could predict spinal structural damage in axial spondyloarthritis (axSpA) in a…”
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    Journal Article
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    Male patients with primary Sjögren's syndrome: A distinct clinical subgroup? by Park, Youngjae, Lee, Jennifer, Park, Sung‐Hwan, Kwok, SeungKi

    “…Aim Because the clinical and immunologic phenotypes of male primary Sjögren's syndrome (pSS) patients have not been fully elucidated, we aimed to investigate…”
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    Journal Article
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    Epigenetic analysis in rheumatoid arthritis synoviocytes by Ham, Seokjin, Bae, Jae-Bum, Lee, Suman, Kim, Bong-Jo, Han, Bok-Ghee, Kwok, Seung-Ki, Roh, Tae-Young

    Published in Experimental & molecular medicine (22-02-2019)
    “…Rheumatoid arthritis (RA) is a complex chronic systematic disease with progressive destruction of the joints by invasive synoviocytes. To characterize the key…”
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    Lactobacillus acidophilus Supplementation Exerts a Synergistic Effect on Tacrolimus Efficacy by Modulating Th17/Treg Balance in Lupus-Prone Mice via the SIGNR3 Pathway by Kim, Da Som, Park, Youngjae, Choi, Jeong-Won, Park, Sung-Hwan, Cho, Mi-La, Kwok, Seung-Ki

    Published in Frontiers in immunology (10-12-2021)
    “…Tacrolimus (Tac) is an immunosuppressant used in the treatment of systemic lupus erythematosus (SLE); however, it induces T cell subset imbalances by reducing…”
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    Baricitinib Attenuates Autoimmune Phenotype and Podocyte Injury in a Murine Model of Systemic Lupus Erythematosus by Lee, Jaeseon, Park, Youngjae, Jang, Se Gwang, Hong, Seung-Min, Song, Young-Seok, Kim, Min-Jun, Baek, SeungYe, Park, Sung-Hwan, Kwok, Seung-Ki

    Published in Frontiers in immunology (23-08-2021)
    “…Baricitinib, a selective inhibitor for janus kinase (JAK) 1 and JAK2, is approved for use in rheumatoid arthritis. Systemic lupus erythematosus (SLE) is…”
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    Myeloid-derived suppressor cells therapy enhance immunoregulatory properties in acute graft versus host disease with combination of regulatory T cells by Park, Min-Jung, Baek, Jin-Ah, Kim, Se-Young, Jung, Kyung-Ah, Choi, Jeong Won, Park, Sung-Hwan, Kwok, Seung-Ki, Cho, Mi-La

    Published in Journal of translational medicine (14-12-2020)
    “…Myeloid-derived suppressor cells (MDSCs) play a critical role in modulating the immune response and promoting immune tolerance in models of autoimmunity and…”
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    Adipose tissue-derived mesenchymal stem cells induce expansion of interleukin-10-producing regulatory B cells and ameliorate autoimmunity in a murine model of systemic lupus erythematosus by Park, Min-Jung, Kwok, Seung-Ki, Lee, Sung-Hee, Kim, Eun-Kyung, Park, Sung-Hwan, Cho, Mi-La

    Published in Cell transplantation (01-11-2015)
    “…Mesenchymal stem cells (MSCs) are multipotent cells characterized by immunomodulatory properties and are therefore considered a promising tool for the…”
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