Search Results - "Seuanez, Hector"

Large ancestral effective population size explains the difficult phylogenetic placement of owl monkeys by Schrago, Carlos G., Seuánez, Hector N.

“…The phylogenetic position of owl monkeys, grouped in the genus Aotus, has been a controversial issue for understanding Neotropical primate evolution…”
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Changes in selection intensity on the mitogenome of subterranean and fossorial rodents respective to aboveground species by Tavares, William Corrêa, Seuánez, Hector N.

“…Several rodent lineages independently acquired the ability to dig complex networks of tunnels where fossorial and subterranean species spend part or their…”
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Investigation of major genetic alterations in neuroblastoma by Costa, Régis Afonso, Seuánez, Héctor N.

“…Neuroblastoma (NB) is the most common extracranial solid tumor in childhood. This malignancy shows a wide spectrum of clinical outcome and its prognosis is…”
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Changes in Ontogenetic Allometry and their Role in the Emergence of Cranial Morphology in Fossorial Spiny Rats (Echimyidae, Hystricomorpha, Rodentia) by Tavares, William Corrêa, Pessôa, Leila Maria, Seuánez, Héctor N.

“…All evolutionary modifications of morphology in adult animals presuppose occurrence of changes in developmental programming. While some developmental changes…”
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The Brazilian Hereditary Cancer Network: historical aspects and challenges for clinical cancer genetics in the public health care system in Brazil by Ashton-Prolla, Patricia, Seuanez, Hector N

“…Although the majority of cancers result from complex interactions between genetic, epigenetic and environmental factors, inherited germ-line mutations with…”
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The germline mutational landscape of BRCA1 and BRCA2 in Brazil by Palmero, Edenir Inêz, Carraro, Dirce Maria, Alemar, Barbara, Moreira, Miguel Angelo Martins, Ribeiro-Dos-Santos, Ândrea, Abe-Sandes, Kiyoko, Galvão, Henrique Campos Reis, Reis, R. M., de Pádua Souza, Cristiano, Campacci, Natalia, et. al

“…The detection of germline mutations in BRCA1 and BRCA2 is essential to the formulation of clinical management strategies, and in Brazil, there is limited…”
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Stability and acceleration of phenotypic evolution in spiny rats (Trinomys, Echimyidae) across different environments by Tavares, William Corrêa, Pessôa, Leila Maria, Seuánez, Hector N.

“…Trinomys is a very diverse mammalian genus of eastern Brazil, comprising ten species. Eight of them have remained in their original biome, the Atlantic Forest,…”
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Reanalysis of the biogeographical hypothesis of range expansion between robust and gracile capuchin monkeys by Nascimento, Fabrícia F., Lazar, Ana, Seuánez, Héctor N., Bonvicino, Cibele R.

“…The data used by Lynch Alfaro et al., (2012a, Journal of Biogeography, 39, 272-288) and the biogeographical hypothesis postulated by these authors to explain…”
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The human retinoblastoma susceptibility gene (RB1): an evolutionary story in primates by Viana, Maria C., Tavares, William C., Brant, Ayslan C., Boroni, Mariana, Seuánez, Héctor N.

“…The tumor suppressor gene RB1 (Human Retinoblastoma Susceptibility Gene) plays a prominent role in normal development, gene transcription, DNA replication,…”
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Plio-Pleistocene history of the endangered spiny rat Trinomys eliasi (Echimyidae) from Rio de Janeiro, Brazil by Tavares, William Corrêa, Pessôa, Leila Maria, Seuánez, Hector N.

“…Trinomys eliasi is an endangered species of spiny rat endemic to a small area in the lowlands of Rio de Janeiro state (Brazil). Limited data on its biology and…”
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Array CGH Analysis of Paired Blood and Tumor Samples from Patients with Sporadic Wilms Tumor by Cabral de Almeida Cardoso, Leila, Rodriguez-Laguna, Lara, Del Carmen Crespo, María, Vallespín, Elena, Palomares-Bralo, María, Martin-Arenas, Rubén, Rueda-Arenas, Inmaculada, Silvestre de Faria, Paulo Antonio, García-Miguel, Purificación, Lapunzina, Pablo, Regla Vargas, Fernando, Seuanez, Hector N, Martínez-Glez, Víctor

“…Wilms tumor (WT), the most common cancer of the kidney in infants and children, has a complex etiology that is still poorly understood. Identification of…”
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Rare nasal cleft in a patient with holoprosencephaly due to a mutation in the ZIC2 gene by Savastano, Clarice Pagani, Bernardi, Pricila, Seuánez, Hector N., Moreira, Miguel Ângelo Martins, Orioli, Iêda Maria

“…BACKGROUND Holoprosencephaly (HPE) is a spectrum of midline malformations of the prosencephalon generally reflected in a continuum of midline facial anomalies…”
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Impact of long‐term chromosomal shuffling on the multispecies coalescent analysis of two anthropoid primate lineages by Schrago, Carlos G., Mello, Beatriz, Pereira, Anieli G., Furtado, Carolina, Seuánez, Hector N.

“…Multispecies coalescent (MSC) theory assumes that gene trees inferred from individual loci are independent trials of the MSC process. As genes might be…”
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Systematics and Acceleration of Cranial Evolution in Cerradomys (Rodentia, Cricetidae, Sigmodontinae) of Quaternary Sandy Plains in Southeastern Brazil by Tavares, William Corrêa, Pessôa, Leila Maria, Seuánez, Hector N.

“…The genus Cerradomys , comprising eight species, is distributed mainly in transitional, dry, open and inland South American biomes like Caatinga, Cerrado, and…”
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Positive selection along the evolution of primate mitogenomes by Menezes, Albert N, Viana, Maria Carolina, Furtado, Carolina, Schrago, Carlos G, Seuánez, Héctor N

“…The mitochondrial genomes of four neotropical primates, Aotus infulatus, Chiropotes israelita, Callimico goeldii and Callicebus lugens were sequenced and…”
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A molecular phylogeny of living primates by Perelman, Polina, Johnson, Warren E, Roos, Christian, Seuánez, Hector N, Horvath, Julie E, Moreira, Miguel A M, Kessing, Bailey, Pontius, Joan, Roelke, Melody, Rumpler, Yves, Schneider, Maria Paula C, Silva, Artur, O'Brien, Stephen J, Pecon-Slattery, Jill

“…Comparative genomic analyses of primates offer considerable potential to define and understand the processes that mold, shape, and transform the human genome…”
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Mutations, Differential Gene Expression, and Chimeric Transcripts in Esophageal Squamous Cell Carcinoma Show High Heterogeneity by Souza-Santos, Paulo Thiago de, Soares Lima, Sheila Coelho, Nicolau-Neto, Pedro, Boroni, Mariana, Meireles Da Costa, Nathalia, Brewer, Lilian, Menezes, Albert Nobre, Furtado, Carolina, Moreira, Miguel Angelo Martins, Seuanez, Hector N., de Almeida Simão, Tatiana, Ribeiro Pinto, Luis Felipe

“…Esophageal squamous cell carcinoma (ESCC) is a frequent and lethal neoplasia. As recent advances in targeted therapy have not improved ESCC prognosis,…”
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Polymorphisms in the α4 integrin of neotropical primates: insights for binding of natural ligands and HIV-1 gp120 to the human α4β7 by Darc, Mirela, Hait, Sabrina H, Soares, Esmeralda A, Cicala, Claudia, Seuanez, Hector N, Machado, Elizabeth S, Arthos, James A, Soares, Marcelo A

“…The α4 integrin subunit associates with β7 and β1 and plays important roles in immune function and cell trafficking. The gut-homing receptor α4β7 has been…”
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Family-based genome-wide association study in Patagonia confirms the association of the DMD locus and cleft lip and palate by Fonseca, Renata F., de Carvalho, Flávia M., Poletta, Fernando A., Montaner, David, Dopazo, Joaquin, Mereb, Juan C., Moreira, Miguel A. M., Seuanez, Hector N., Vieira, Alexandre R., Castilla, Eduardo E., Orioli, Iêda M.

“…The etiology of cleft lip with or without cleft palate (CL±P) is complex and heterogeneous, and multiple genetic and environmental factors are involved. Some…”
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Multispecies coalescent analysis of the early diversification of neotropical primates: phylogenetic inference under strong gene trees/species tree conflict by Schrago, Carlos G, Menezes, Albert N, Furtado, Carolina, Bonvicino, Cibele R, Seuanez, Hector N

“…Neotropical primates (NP) are presently distributed in the New World from Mexico to northern Argentina, comprising three large families, Cebidae, Atelidae, and…”
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