Search Results - "Sethi, Debarati"

Molecular Characterization of Mutant Mouse Strains Generated from the EUCOMM/KOMP-CSD ES Cell Resource by Ryder, Edward, Gleeson, Diane, Sethi, Debarati, Vyas, Sapna, Miklejewska, Evelina, Dalvi, Priya, Habib, Bishoy, Cook, Ross, Hardy, Matthew, Jhaveri, Kalpesh, Bottomley, Joanna, Wardle-Jones, Hannah, Bussell, James N, Houghton, Richard, Salisbury, Jennifer, Skarnes, William C, Ramirez-Solis, Ramiro

“…The Sanger Mouse Genetics Project generates knockout mice strains using the EUCOMM/KOMP-CSD embryonic stem (ES) cell collection and characterizes the…”
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Targeting of NAT10 enhances healthspan in a mouse model of human accelerated aging syndrome by Balmus, Gabriel, Larrieu, Delphine, Barros, Ana C., Collins, Casey, Abrudan, Monica, Demir, Mukerrem, Geisler, Nicola J., Lelliott, Christopher J., White, Jacqueline K., Karp, Natasha A., Atkinson, James, Kirton, Andrea, Jacobsen, Matt, Clift, Dean, Rodriguez, Raphael, Adams, David J., Jackson, Stephen P.

“…Hutchinson-Gilford Progeria Syndrome (HGPS) is a rare, but devastating genetic disease characterized by segmental premature aging, with cardiovascular disease…”
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High-throughput genotyping of high-homology mutant mouse strains by next-generation sequencing by Gleeson, Diane, Sethi, Debarati, Platte, Radka, Burvill, Jonathan, Barrett, Daniel, Akhtar, Shaheen, Bruntraeger, Michaela, Bottomley, Joanna, Mouse Genetics Project, Sanger, Bussell, James, Ryder, Edward

“…•Next generation sequencing is a scalable solution to genotyping mutant mice.•Ratios of wild type and mutant sequence counts are used to call the…”
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Genetic determinants of micronucleus formation in vivo by Adams, D. J., Barlas, B., McIntyre, R. E., Salguero, I., van der Weyden, L., Barros, A., Vicente, J. R., Karimpour, N., Haider, A., Ranzani, M., Turner, G., Thompson, N. A., Harle, V., Olvera-León, R., Robles-Espinoza, C. D., Speak, A. O., Geisler, N., Weninger, W. J., Geyer, S. H., Hewinson, J., Karp, N. A., Fu, B., Yang, F., Kozik, Z., Choudhary, J., Yu, L., van Ruiten, M. S., Rowland, B. D., Lelliott, C. J., del Castillo Velasco-Herrera, M., Verstraten, R., Bruckner, L., Henssen, A. G., Rooimans, M. A., de Lange, J., Mohun, T. J., Arends, M. J., Kentistou, K. A., Coelho, P. A., Zhao, Y., Zecchini, H., Perry, J. R. B., Jackson, S. P., Balmus, G.

“…Genomic instability arising from defective responses to DNA damage 1 or mitotic chromosomal imbalances 2 can lead to the sequestration of DNA in aberrant…”
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The role of sphingosine-1-phosphate transporter Spns2 in immune system function by Nijnik, Anastasia, Clare, Simon, Hale, Christine, Chen, Jing, Raisen, Claire, Mottram, Lynda, Lucas, Mark, Estabel, Jeanne, Ryder, Edward, Adissu, Hibret, Adams, Niels C, Ramirez-Solis, Ramiro, White, Jacqueline K, Steel, Karen P, Dougan, Gordon, Hancock, Robert E W

“…Sphingosine-1-phosphate (S1P) is lipid messenger involved in the regulation of embryonic development, immune system functions, and many other physiological…”
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Rapid conversion of EUCOMM/KOMP-CSD alleles in mouse embryos using a cell-permeable Cre recombinase by Ryder, Edward, Doe, Brendan, Gleeson, Diane, Houghton, Richard, Dalvi, Priya, Grau, Evelyn, Habib, Bishoy, Miklejewska, Evelina, Newman, Stuart, Sethi, Debarati, Sinclair, Caroline, Vyas, Sapna, Wardle-Jones, Hannah, Bottomley, Joanna, Bussell, James, Galli, Antonella, Salisbury, Jennifer, Ramirez-Solis, Ramiro

“…We describe here use of a cell-permeable Cre to efficiently convert the EUCOMM/KOMP-CSD tm1a allele to the tm1b form in preimplantation mouse embryos in a…”
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A gene expression resource generated by genome-wide lacZ profiling in the mouse by Tuck, Elizabeth, Estabel, Jeanne, Oellrich, Anika, Maguire, Anna Karin, Adissu, Hibret A, Souter, Luke, Siragher, Emma, Lillistone, Charlotte, Green, Angela L, Wardle-Jones, Hannah, Carragher, Damian M, Karp, Natasha A, Smedley, Damian, Adams, Niels C, Bussell, James N, Adams, David J, Ramírez-Solis, Ramiro, Steel, Karen P, Galli, Antonella, White, Jacqueline K

“…Knowledge of the expression profile of a gene is a critical piece of information required to build an understanding of the normal and essential functions of…”
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Genomic analysis of a novel spontaneous albino C57BL/6N mouse strain by Ryder, Edward, Wong, Kim, Gleeson, Diane, Keane, Thomas M., Sethi, Debarati, Vyas, Sapna, Wardle-Jones, Hannah, Bussell, James N., Houghton, Richard, Salisbury, Jennifer, Harvey, Nina, Adams, David J., Ramirez-Solis, Ramiro

“…We report an albino C57BL/6N mouse strain carrying a spontaneous mutation in the tyrosinase gene (C57BL/6N‐TyrcWTSI). Deep whole genome sequencing of founder…”
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