Search Results - "Seth, Chandan"

Metastases and Colon Cancer Tumor Growth Display Divergent Responses to Modulation of Canonical WNT Signaling by Seth, Chandan, Ruiz i Altaba, Ariel

“…Human colon cancers commonly harbor loss of function mutations in APC, a repressor of the canonical WNT pathway, thus leading to hyperactive WNT-TCF signaling…”
Get full text

A novel genome‐wide in vivo screen for metastatic suppressors in human colon cancer identifies the positive WNT‐TCF pathway modulators TMED3 and SOX12 by Duquet, Arnaud, Melotti, Alice, Mishra, Sonakshi, Malerba, Monica, Seth, Chandan, Conod, Arwen, Ruiz i Altaba, Ariel

“…The progression of tumors to the metastatic state involves the loss of metastatic suppressor functions. Finding these, however, is difficult as in vitro assays…”
Get full text

Correction: Metastases and Colon Cancer Tumor Growth Display Divergent Responses to Modulation of Canonical WNT Signaling by Seth, Chandan, Ruiz I Altaba, Ariel

“…[This corrects the article DOI: 10.1371/journal.pone.0150697.]…”
Get full text

Long-Lasting WNT-TCF Response Blocking and Epigenetic Modifying Activities of Withanolide F in Human Cancer Cells by Seth, Chandan, Mas, Christophe, Conod, Arwen, Mueller, Jens, Siems, Karsten, Kuciak, Monika, Borges, Isabel, Ruiz I Altaba, Ariel

“…The WNT-TCF signaling pathway participates in adult tissue homeostasis and repair, and is hyperactive in a number of human diseases including cancers of the…”
Get full text

Characterization of Leishmania donovani aquaporins shows presence of subcellular aquaporins similar to tonoplast intrinsic proteins of plants by Biyani, Neha, Mandal, Swati, Seth, Chandan, Saint, Malika, Natarajan, Krishnamurthy, Ghosh, Indira, Madhubala, Rentala

“…Leishmania donovani, a protozoan parasite, resides in the macrophages of the mammalian host. The aquaporin family of proteins form important components of the…”
Get full text

Defining a metabolic landscape of tumours: genome meets metabolism by Seth Nanda, Chandan, Venkateswaran, Sharavan Vishaan, Patani, Neill, Yuneva, Mariia

“…Cancer is a complex disease of multiple alterations occuring at the epigenomic, genomic, transcriptomic, proteomic and/or metabolic levels. The contribution of…”
Get full text

Contamination of Indian sea salts with microplastics and a potential prevention strategy by Seth, Chandan Krishna, Shriwastav, Amritanshu

“…This study reports the contamination of Indian sea salts with different microplastic particles, as a consequence of using contaminated sea water. Samples from…”
Get full text

Solitary Laryngeal Neurofibroma in an Elderly Patient With von Recklinghausen's Disease by Seth, Chandan, Dutta, Mainak, Kadambott, Sharafali

Get full text

Solitary Isolated Oropharyngeal Neurofibroma Presenting With Dysphagia in the Setting of Von Recklinghausen's Disease by Sarkar, Shrita, Seth, Chandan, Dutta, Mainak, Bandyopadhyay, Saumendra Nath

“…A 24-year-old man with von Recklinghausen's disease presented with complaints of difficulty in swallowing for 6 months and change of voice for 3 months. He…”
Get full text

Primary Isolated Solitary Schwannoma of the Uvula by Seth, Chandan, Dutta, Mainak, Bandyopadhyay, Saumendra Nath

Get full text

Sequestered, Iatrogenic Epidermoid Implantation Cysts Associated With Retroauricular (Wilde's) Incision by Dutta, Mainak, Kadambott, Sharafali, Kar, Sutarthi, Arbaz, Mirza, Seth, Chandan

“…To report two patients with iatrogenic, epidermoid implantation cysts associated with the standard retroauricular (Wilde's) incision, to establish their…”
Get full text

The amino acid transporter SLC7A5 is required for efficient growth of KRAS-mutant colorectal cancer by Najumudeen, Arafath K., Ceteci, Fatih, Fey, Sigrid K., Hamm, Gregory, Steven, Rory T., Hall, Holly, Nikula, Chelsea J., Dexter, Alex, Murta, Teresa, Race, Alan M., Sumpton, David, Vlahov, Nikola, Gay, David M., Knight, John R. P., Jackstadt, Rene, Leach, Joshua D. G., Ridgway, Rachel A., Johnson, Emma R., Nixon, Colin, Hedley, Ann, Gilroy, Kathryn, Clark, William, Malla, Sudhir B., Dunne, Philip D., Rodriguez-Blanco, Giovanny, Critchlow, Susan E., Mrowinska, Agata, Malviya, Gaurav, Solovyev, Dmitry, Brown, Gavin, Lewis, David Y., Mackay, Gillian M., Strathdee, Douglas, Tardito, Saverio, Gottlieb, Eyal, Takats, Zoltan, Barry, Simon T., Goodwin, Richard J. A., Bunch, Josephine, Bushell, Martin, Campbell, Andrew D., Sansom, Owen J.

“…Oncogenic KRAS mutations and inactivation of the APC tumor suppressor co-occur in colorectal cancer (CRC). Despite efforts to target mutant KRAS directly, most…”
Get full text

How Does Preoperative Pure Tone Audiometry Relate to the Findings at Surgery to Explain the Hearing Status in Chronic Otitis Media? by Kadambott, Sharafali, Kumar Gure, Prasanta, Ghatak, Soumya, Dutta, Mainak, Seth, Chandan, Das, Saumik, Sinha, Ramanuj

“…Pure tone audiometry (PTA) guides surgical decision-making in chronic otitis media (COM), and PTA values depend upon the type and extent of COM. Our…”
Get full text

Genomic profiling in pancreatic cancer reveals spatial genetic heterogeneity but spatial transcriptomic homogeneity by Sivakumar, Shivan, Rana, Anas, Seth, Chandan, de Santiago, Ines, Soonawalla, Zahir, Morgan, Robert, Rendek, Aniko, Silva, Michael, Reddy, Srikanth, Jones, Stephanie, Nicod, Jerome, Turnquist, Casmir, Tandon, Ruchi, O’Neill, Eric, Lord, Simon, Dustin, Michael, Taylor, Jenny, Middleton, Mark, Yau, Christopher

Get full text

A novel genome‐wide in vivo screen for metastatic suppressors in human colon cancer identifies the positive WNT ‐ TCF pathway modulators TMED 3 and SOX 12 by Duquet, Arnaud, Melotti, Alice, Mishra, Sonakshi, Malerba, Monica, Seth, Chandan, Conod, Arwen, Ruiz i Altaba, Ariel

“…Abstract The progression of tumors to the metastatic state involves the loss of metastatic suppressor functions. Finding these, however, is difficult as in…”
Get full text

Development of a kidney cancer ex vivo t umor model and image-based artificial intelligence tool for precision immunotherapy and combination therapy testing by Peerani, Eleonora, Kearney, Jay, Wiskerke, Demi Annemarie, Richardson, Thomas David Laurent, Primo, Gastón Augustin, Nan, Keqian, Iori, Francesco, Tham, Elli, de Fraine, George Richard Tiger Bevan, Crawley, Aston Martin, Seth Nanda, Chandan, Williams, Matthew, Tran, Maxine Gia Binh, Ranatunga, Duleek Nimantha Bandara

“…e16525 Background: Immuno-oncology (IO) initiated a major shift in the cancer treatment paradigm, as therapies no longer target cancer cells directly but…”
Get full text