Search Results - "Sesti, Fabiola"

Non-enzymatic post-translational protein modifications and proteostasis network deregulation in carcinogenesis by Trougakos, Ioannis P., Sesti, Fabiola, Tsakiri, Eleni, Gorgoulis, Vassilis G.

“…Organisms are constantly challenged by stressors and thus the maintenance of biomolecules functionality is essential for the assurance of cellular homeostasis…”
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TGFβ-induced c-Myb affects the expression of EMT-associated genes and promotes invasion of ER+ breast cancer cells by Cesi, Vincenzo, Casciati, Arianna, Sesti, Fabiola, Tanno, Barbara, Calabretta, Bruno, Raschellà, Giuseppe

“…Advanced breast cancer cells acquire metastatic properties in response to TGFβ. We show here that the expression of c-Myb increases in TGFβ-treated ER + breast…”
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Expression of Slug Is Regulated by c-Myb and Is Required for Invasion and Bone Marrow Homing of Cancer Cells of Different Origin[S] by Tanno, Barbara, Sesti, Fabiola, Cesi, Vincenzo, Bossi, Gianluca, Ferrari-Amorotti, Giovanna, Bussolari, Rita, Tirindelli, Donatella, Calabretta, Bruno, Raschellà, Giuseppe

“…In metastatic cancer cells, the process of invasion is regulated by several transcription factors that induce changes required for migration and resistance to…”
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Interleukin-6 affects cell death escaping mechanisms acting on Bax-Ku70-Clusterin interactions in human colon cancer progression by Pucci, Sabina, Mazzarelli, Paola, Sesti, Fabiola, Boothman, David A., Spagnoli, Luigi G.

“…Activation of pro-survival pathways and apoptotic cell death escape are considered hallmarks of oncogenic cell transformation. Tissue microenvironment strongly…”
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Activity of tyrosine kinase inhibitor Dasatinib in neuroblastoma cells in vitro and in orthotopic mouse model by Vitali, Roberta, Mancini, Camillo, Cesi, Vincenzo, Tanno, Barbara, Piscitelli, Marta, Mancuso, Mariateresa, Sesti, Fabiola, Pasquali, Emanuela, Calabretta, Bruno, Dominici, Carlo, Raschellà, Giuseppe

“…Stage 4 neuroblastoma (NB) is a devastating childhood cancer whose poor outcome has remained essentially unchanged in the last 20 years. Receptor tyrosine…”
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Carnitine palmitoyltransferase I in human carcinomas: A novel role in histone deacetylation? by Mazzarelli, Paola, Pucci, Sabina, Bonanno, Elena, Sesti, Fabiola, Calvani, Menotti, Giusto Spagnoli, Luigi

“…Carnitine palmitoyl transferase I (CPT1) catalyzes the transport of long-chain fatty acids into mitochondria for β-oxidation. A link between CPT1 and apoptosis…”
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Erratum to Sabina Pucci et al., Cell Cycle Volume 8, Issue 3; pp. 473-481 by Pucci, Sabina, Mazzarelli, Paola, Sesti, Fabiola, Boothman, David A., Spagnoli, Luigi G.

“…In the report "Interleukin-6 affects cell death escaping mechanisms acting on Bax-Ku70-Clusterin interactions in human colon cancer progression" by Sabina…”
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Oxidative stress-mediated biomolecular damage and inflammation in tumorigenesis by Sesti, Fabiola, Tsitsilonis, Ourania E, Kotsinas, Athanassios, Trougakos, Ioannis P

“…At the cellular level, free radicals are tightly controlled by an inducible antioxidant program, since at low non-hazardous amounts they contribute to…”
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Clusterin overexpression in mice exacerbates diabetic phenotypes but suppresses tumor progression in a mouse melanoma model by Cheimonidi, Christina, Grivas, Ioannis N, Sesti, Fabiola, Kavrochorianou, Nadia, Gianniou, Despoina D, Taoufik, Era, Badounas, Fotis, Papassideri, Issidora, Rizzi, Federica, Tsitsilonis, Ourania E, Haralambous, Sylva, Trougakos, Ioannis P

“…Clusterin (CLU) is an ATP-independent small heat shock protein-like chaperone, which functions both intra- and extra-cellularly. Consequently, it has been…”
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Abstract B73: Proteostasis network modules as molecular targets for cancer therapeutics by Komseli, Eirini-Stavroula, Sesti, Fabiola, Evangelou, Konstantinos, Cheimonidou, Christina, Kotsinas, Athanassios, Gorgoulis, Vassilis, Trougakos, Ioannis P.

“…The maintenance of biomolecules functionality is essential for the assurance of cellular homeostasis. At the proteome level this is achieved by the action of a…”
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Clusterin in Stool: A New Biomarker for Colon Cancer Screening? by PUCCI, Sabina, BONANNO, Elena, SESTI, Fabiola, MAZZARELLI, Paola, MAURIELLO, Alessandro, RICCI, Federico, BIONDI ZOCCAI, Giuseppe, RULLI, Francesco, GALATA, Gabriele, SPAGNOLI, Luigi G

“…The identification of useful markers for early diagnosis of human colon cancer is a major goal still in progress. Clusterin is a pleiotropic protein with a…”
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Persistent Chlamydia pneumoniae Infection of Cardiomyocytes Is Correlated with Fatal Myocardial Infarction by Spagnoli, Luigi Giusto, Pucci, Sabina, Bonanno, Elena, Cassone, Antonio, Sesti, Fabiola, Ciervo, Alessandra, Mauriello, Alessandro

“…Acute myocardial infarction (AMI) associated with unfavorable prognosis is likely to be the consequence of a diffuse active chronic inflammatory process that…”
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Modulation of Ku70/80, clusterin/ApoJ isoforms and Bax expression in indocyanine-green-mediated photo-oxidative cell damage by Ricci, Federico, Pucci, Sabina, Sesti, Fabiola, Missiroli, Filippo, Cerulli, Luciano, Spagnoli, Luigi Giusto

“…In order to characterize the biological effects and molecular mechanism underlying indocyanine-green (ICG)-mediated photo-oxidative cell damage, human cultured…”
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Stool test for colorectal cancer screening: What is going on? by Bonanno, Elena, Rulli, Francesco, Galatà, Gabriele, Pucci, Sabina, Sesti, Fabiola, Maria Farinon, Attilio, Giusto Spagnoli, Luigi

“…Summary Given the increasing incidence of colorectal cancer (CRC), performing new and cost-effective stool tests is of particular importance for early…”
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Insulin-like Growth Factor Binding Protein 5: Contribution to Growth and Differentiation of Neuroblastoma Cells by CESI, VINCENZO, VITALI, ROBERTA, TANNO, BARBARA, GIUFFRIDA, MARIA LAURA, SESTI, FABIOLA, MANCINI, CAMILLO, RASCHELLÀ, GIUSEPPE

“…: Neuroblastoma (NB) is a childhood tumor that depends on insulin‐like growth factors (IGFs) for its growth and metastatic spread. Some metastatic NBs acquire…”
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