Search Results - "Sessions, Dane T."
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Opa1 and Drp1 reciprocally regulate cristae morphology, ETC function, and NAD+ regeneration in KRas-mutant lung adenocarcinoma
Published in Cell reports (Cambridge) (13-12-2022)“…Oncogenic KRas activates mitochondrial fission through Erk-mediated phosphorylation of the mitochondrial fission GTPase Drp1. Drp1 deletion inhibits…”
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Journal Article -
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Mitochondrial dynamics in cancer stem cells
Published in Cellular and molecular life sciences : CMLS (01-04-2021)“…Many tumors are now understood to be heterogenous cell populations arising from a minority of epithelial-like cancer stem cells (CSCs). CSCs demonstrate…”
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Journal Article -
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Mito Hacker: a set of tools to enable high-throughput analysis of mitochondrial network morphology
Published in Scientific reports (03-11-2020)“…Mitochondria are highly dynamic organelles that can exhibit a wide range of morphologies. Mitochondrial morphology can differ significantly across cell types,…”
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Journal Article