Search Results - "Sershen, Henry"

Effects of transcranial direct current stimulation (tDCS) on cognition, symptoms, and smoking in schizophrenia: A randomized controlled study by Smith, Robert C, Boules, Sylvia, Mattiuz, Sanela, Youssef, Mary, Tobe, Russell H, Sershen, Henry, Lajtha, Abel, Nolan, Karen, Amiaz, Revital, Davis, John M

“…Abstract Schizophrenia is characterized by cognitive deficits which persist after acute symptoms have been treated or resolved. Transcranial direct current…”
Get full text

Rodent Mismatch Negativity/theta Neuro-Oscillatory Response as a Translational Neurophysiological Biomarker for N-Methyl-D-Aspartate Receptor-Based New Treatment Development in Schizophrenia by Lee, Migyung, Balla, Andrea, Sershen, Henry, Sehatpour, Pejman, Lakatos, Peter, Javitt, Daniel C

“…Deficits in the generation of auditory mismatch negativity (MMN) generation are among the most widely replicated neurophysiological abnormalities in…”
Get full text

Psilocybin sex-dependently reduces alcohol consumption in C57BL/6J mice by Alper, Kenneth, Cange, Janelle, Sah, Ria, Schreiber-Gregory, Deanna, Sershen, Henry, Vinod, K Yaragudri

“…The classical psychedelic psilocybin is of interest as a treatment for alcohol use disorder (AUD). This study investigated the effects of psilocybin on…”
Get full text

Varenicline Effects on Smoking, Cognition, and Psychiatric Symptoms in Schizophrenia: A Double-Blind Randomized Trial by Smith, Robert C, Amiaz, Revital, Si, Tian-Mei, Maayan, Lawrence, Jin, Hua, Boules, Sylvia, Sershen, Henry, Li, Chunbo, Ren, Juanjuan, Liu, Yanhong, Youseff, Mary, Lajtha, Abel, Guidotti, Alessandro, Weiser, Mark, Davis, John M

“…Schizophrenic patients have a high rate of smoking and cognitive deficits which may be related to a decreased number or responsiveness of nicotinic receptors…”
Get full text

LSD Administered as a Single Dose Reduces Alcohol Consumption in C57BL/6J Mice by Alper, Kenneth, Dong, Bin, Shah, Relish, Sershen, Henry, Vinod, K Yaragudri

“…There is a substantive clinical literature on classical hallucinogens, most commonly lysergic acid diethylamide (LSD) for the treatment of alcohol use…”
Get full text

Relationship of cognitive measures to mRNA levels in lymphocytes from patients with schizophrenia and controls by Smith, Robert C., Sershen, Henry, Chen, AnMei, Jin, Hua, Guidotti, Alexandro, Davis, John M.

“…Patients with schizophrenia show substantial cognitive deficits and abnormalities in neurotransmitter-related levels of mRNA in brain or peripheral blood…”
Get full text

Deficits in odor discrimination versus odor identification in patients with schizophrenia and negative correlations with GABAergic and DNA methyltransferase mRNAs in lymphocytes by Smith, Robert C, Sershen, Henry, Youssef, Mary, Lajtha, Abel, Jin, Hua, Zhang, Mumei, Chen, Anmei, Guidotti, Alessandro, Davis, John M

“…People with schizophrenia have been reported to show deficits in tests of olfactory function. DNA methylation and GABAergic input have been implicated in…”
Get full text

Functional connectivity fMRI in mouse brain at 7T using isoflurane by Guilfoyle, David N., Gerum, Scott V., Sanchez, Jamie L., Balla, Andrea, Sershen, Henry, Javitt, Daniel C., Hoptman, Matthew J.

“…► We report fMRI functional connectivity measures in mouse brain. ► Reliable functional connectivity measures can be obtained using isoflurane as the…”
Get full text

Changes in Expression of DNA-Methyltransferase and Cannabinoid Receptor mRNAs in Blood Lymphocytes After Acute Cannabis Smoking by Smith, Robert C., Sershen, Henry, Janowsky, David S., Lajtha, Abel, Grieco, Matthew, Gangoiti, Jon A., Gertsman, Ilya, Johnson, Wynnona S., Marcotte, Thomas D., Davis, John M.

“…Background Cannabis use is a component risk factor for the manifestation of schizophrenia. The biological effects of cannabis include effects on epigenetic…”
Get full text

Cocaine perturbs mitovesicle biology in the brain by D'Acunzo, Pasquale, Ungania, Jonathan M., Kim, Yohan, Barreto, Bryana R., DeRosa, Steven, Pawlik, Monika, Canals‐Baker, Stefanie, Erdjument‐Bromage, Hediye, Hashim, Audrey, Goulbourne, Chris N., Neubert, Thomas A., Saito, Mariko, Sershen, Henry, Levy, Efrat

“…Cocaine, an addictive psychostimulant, has a broad mechanism of action, including the induction of a wide range of alterations in brain metabolism and…”
Get full text

Obituary—Abel Lajtha (1922–2024) by Sershen, Henry

“…With sadness, the International Society for Neurochemistry (ISN) and the Journal of Neurochemistry (JNC) mourn the loss of one of the founding members of the…”
Get full text

Correction: Arne Schousboe: in Memoriam (1944–2024) by Sershen, Henry

Get full text

Abel Lajtha: In Memoriam (1922–2024) by Sershen, Henry

Get full text

Arne Schousboe: In Memoriam (1944–2024) by Sershen, Henry

Get full text

Translational neurophysiological biomarkers of N-methyl-d-aspartate receptor dysfunction in serine racemase knockout mice by Balla, Andrea, Ginsberg, Stephen D., Abbas, Atheir I., Sershen, Henry, Javitt, Daniel C.

“…Alterations in glutamatergic function are well established in schizophrenia (Sz), but new treatment development is hampered by the lack of translational…”
Get full text

Gene expression of methylation cycle and related genes in lymphocytes and brain of patients with schizophrenia and non-psychotic controls by Sershen, Henry, Guidotti, Alessandro, Auta, James, Drnevich, Jenny, Grayson, Dennis R., Veldic, Marin, Meyers, Jordan, Youseff, Mary, Zhubi, Adrian, Faurot, Keturah, Wu, Renrong, Zhao, Jingping, Jin, Hua, Lajtha, Abel, Davis, John M., Smith, Robert C.

“…•Sex influenced the extent to differences in mRNAs in lymphocytes (PBLs) between schizophrenics (CSZ) and controls (NPC). There were differences between in CSZ…”
Get full text

GABAB/NMDA receptor interaction in the regulation of extracellular dopamine levels in rodent prefrontal cortex and striatum by Balla, Andrea, Nattini, Megan E, Sershen, Henry, Lajtha, Abel, Dunlop, David S, Javitt, Daniel C

“…Deficits in N-methyl-D-aspartate receptor (NMDAR)-mediated neurotransmission may underlie dopaminergic hyperactivity in schizophrenia. Dysregulation of the…”
Get full text

Food reward-induced neurotransmitter changes in cognitive brain regions by Fallon, Shaun, Shearman, Erin, Sershen, Henry, Lajtha, Abel

“…Recent evidence indicates that mechanisms involved in reward and mechanisms involved in learning interact, in that reward includes learning processes and…”
Get full text

Reversal of phencyclidine-induced dopaminergic dysregulation by N-methyl-D-aspartate receptor/glycine-site agonists by JAVITT, Daniel C, BALLA, Andrea, BURCH, Sarah, SUCKOW, Ray, SHAN XIE, SERSHEN, Henry

“…N-methyl-D-aspartate (NMDA) receptors may play a critical role in the pathophysiology of schizophrenia. In rodents, NMDA receptor antagonists, such as…”
Get full text

Differential regulation of catechol-O-methyltransferase expression in a mouse model of aggression by Ginsberg, Stephen D., Che, Shaoli, Hashim, Audrey, Zavadil, Jiri, Cancro, Robert, Lee, Sang H., Petkova, Eva, Sershen, Henry W., Volavka, Jan

“…This study was designed to understand molecular and cellular mechanisms underlying aggressive behaviors in mice exposed to repeated interactions in their…”
Get full text