Search Results - "Sersa, Gregor"
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A combination of electrochemotherapy, gene electrotransfer of plasmid encoding canine IL-12 and cytoreductive surgery in the treatment of canine oral malignant melanoma
Published in Research in veterinary science (01-02-2019)“…The aim of this study was to evaluate the safety and efficacy of the combination of electrochemotherapy (ECT) with bleomycin and gene electrotransfer (GET) of…”
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Clinical potential of electroporation for gene therapy and DNA vaccine delivery
Published in Expert opinion on drug delivery (01-02-2016)“…Electroporation allows efficient delivery of DNA into cells and tissues, thereby improving the expression of therapeutic or immunogenic proteins that are…”
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Differential mechanisms associated with vascular disrupting action of electrochemotherapy: intravital microscopy on the level of single normal and tumor blood vessels
Published in PloS one (26-03-2013)“…Electropermeabilization/electroporation (EP) provides a tool for the introduction of molecules into cells and tissues. In electrochemotherapy (ECT), cytotoxic…”
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Safety aspects of atmospheric pressure helium plasma jet operation on skin: In vivo study on mouse skin
Published in PloS one (05-04-2017)“…Biomedical applications of plasma require its efficacy for specific purposes and equally importantly its safety. Herein the safety aspects of cold plasma…”
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Editorial: Pulsed electric field based technologies for oncology applications
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Synergistic effect of cisplatin chemotherapy combined with fractionated radiotherapy regimen in HPV-positive and HPV-negative experimental pharyngeal squamous cell carcinoma
Published in Scientific reports (31-01-2020)“…HPV infection renders oropharyngeal squamous cell carcinomas more radiosensitive, which results in a favorable prognosis for HPV-positive patients treated with…”
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The effectiveness of calcium electroporation combined with gene electrotransfer of a plasmid encoding IL-12 is tumor type-dependent
Published in Frontiers in immunology (25-05-2023)“…In calcium electroporation (CaEP), electroporation enables the cellular uptake of supraphysiological concentrations of Ca , causing the induction of cell…”
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Imaging perfusion changes in oncological clinical applications by hyperspectral imaging: a literature review
Published in Radiology and oncology (13-12-2022)“…Hyperspectral imaging (HSI) is a promising imaging modality that uses visible light to obtain information about blood flow. It has the distinct advantage of…”
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Tumor Radiosensitization by Gene Electrotransfer-Mediated Double Targeting of Tumor Vasculature
Published in International journal of molecular sciences (01-02-2023)“…Targeting the tumor vasculature through specific endothelial cell markers involved in different signaling pathways represents a promising tool for tumor…”
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Long term response of electrochemotherapy with reduced dose of bleomycin in elderly patients with head and neck non-melanoma skin cancer
Published in Radiology and oncology (19-02-2020)“…Background Electrochemotherapy (ECT) is a local cancer treatment based on electroporation where the electric field is used to enhance cell membrane…”
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Electrochemotherapy combined with immunotherapy - a promising potential in the treatment of cancer
Published in Frontiers in immunology (15-01-2024)“…Electrochemotherapy is a novel, locoregional therapy that is used to treat cutaneous and deep-seated tumors. The electric pulses used in electrochemotherapy…”
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Laparoscopic electrochemotherapy for the treatment of hepatocellular carcinoma: Technological advancement
Published in Frontiers in oncology (10-11-2022)“…Electrochemotherapy is an effective treatment modality for hepatocellular carcinoma (HCC). Electrochemotherapy for HCC was initially used in the setting of…”
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Laser speckle contrast imaging of perfusion in oncological clinical applications: a literature review
Published in Radiology and oncology (01-09-2024)“…Laser speckle coherence imaging (LSCI) is an emerging imaging modality that enables noninvasive visualization and assessment of tissue perfusion and…”
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European Research on Electrochemotherapy in Head and Neck Cancer (EURECA) project: Results of the treatment of skin cancer
Published in European journal of cancer (1990) (01-08-2016)“…Abstract Electrochemotherapy is an effective and safe method for local treatment of cutaneous and subcutaneous tumours, where electric pulses cause increased…”
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Electrochemotherapy of Melanoma Cutaneous Metastases in Organ Transplant Recipients: A Systematic Review of Preclinical and Clinical Studies
Published in International journal of molecular sciences (06-05-2023)“…Cutaneous melanoma is a highly aggressive form of skin cancer. The development of immune checkpoint inhibitors (ICIs) has revolutionized the management of…”
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Intradermal DNA vaccination combined with dual CTLA-4 and PD-1 blockade provides robust tumor immunity in murine melanoma
Published in PloS one (31-05-2019)“…We aimed to explore whether the combination of intradermal DNA vaccination, to boost immune response against melanoma antigens, and immune checkpoint blockade,…”
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In vivo real-time monitoring system of electroporation mediated control of transdermal and topical drug delivery
Published in Journal of controlled release (28-12-2013)“…Electroporation (EP) is a physical method for the delivery of molecules into cells and tissues, including the skin. In this study, in order to control the…”
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Treatment of vulvar cancer recurrence with electrochemotherapy: a case-control study
Published in Acta oncologica (21-05-2024)“…Electrochemotherapy (ECT) is a combined treatment method based on electroporation and simultaneous chemotherapy. In cases where radiotherapy has previously…”
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Imaging microvascular changes in nonocular oncological clinical applications by optical coherence tomography angiography: a literature review
Published in Radiology and oncology (01-12-2023)“…Optical coherence tomography angiography (OCTA) is an emerging imaging modality that enables noninvasive visualization and analysis of tumor vasculature. OCTA…”
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Tumor perfusion evaluation using dynamic contrast-enhanced ultrasound after electrochemotherapy and IL-12 plasmid electrotransfer in murine melanoma
Published in Scientific reports (29-06-2021)“…Electrochemotherapy with bleomycin (ECT BLM) is an effective antitumor treatment already used in clinical oncology. However, ECT alone is still considered a…”
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