Search Results - "Serres, Shannah"

Decreasing mutant ATXN1 nuclear localization improves a spectrum of SCA1-like phenotypes and brain region transcriptomic profiles by Handler, Hillary P., Duvick, Lisa, Mitchell, Jason S., Cvetanovic, Marija, Reighard, Molly, Soles, Alyssa, Mather, Kathleen B., Rainwater, Orion, Serres, Shannah, Nichols-Meade, Tessa, Coffin, Stephanie L., You, Yun, Ruis, Brian L., O’Callaghan, Brennon, Henzler, Christine, Zoghbi, Huda Y., Orr, Harry T.

“…Spinocerebellar ataxia type 1 (SCA1) is a dominant trinucleotide repeat neurodegenerative disease characterized by motor dysfunction, cognitive impairment, and…”
Get full text

Mapping SCA1 regional vulnerabilities reveals neural and skeletal muscle contributions to disease by Duvick, Lisa, Southern, W Michael, Benzow, Kellie A, Burch, Zoe N, Handler, Hillary P, Mitchell, Jason S, Kuivinen, Hannah, Gadiparthi, Udaya, Yang, Praseuth, Soles, Alyssa, Sheeler, Carrie A, Rainwater, Orion, Serres, Shannah, Lind, Erin B, Nichols-Meade, Tessa, O'Callaghan, Brennon, Zoghbi, Huda Y, Cvetanovic, Marija, Wheeler, Vanessa C, Ervasti, James M, Koob, Michael D, Orr, Harry T

“…Spinocerebellar ataxia type 1 (SCA1) is a fatal neurodegenerative disease caused by an expanded polyglutamine tract in the widely expressed ataxin-1 (ATXN1)…”
Get full text