Search Results - "Serrano, Myrna"
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Roles of the Microbiota of the Female Reproductive Tract in Gynecological and Reproductive Health
Published in Microbiology and molecular biology reviews (21-12-2022)“…The microbiome of the female reproductive tract defies the convention that high biodiversity is a hallmark of an optimal ecosystem. Although not universally…”
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The truth about metagenomics: quantifying and counteracting bias in 16S rRNA studies
Published in BMC microbiology (21-03-2015)“…Characterizing microbial communities via next-generation sequencing is subject to a number of pitfalls involving sample processing. The observed community…”
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Differences in vaginal microbiome in African American women versus women of European ancestry
Published in Microbiology (Society for General Microbiology) (01-10-2014)“…Women of European ancestry are more likely to harbour a Lactobacillus-dominated microbiome, whereas African American women are more likely to exhibit a diverse…”
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Racioethnic diversity in the dynamics of the vaginal microbiome during pregnancy
Published in Nature medicine (01-06-2019)“…The microbiome of the female reproductive tract has implications for women’s reproductive health. We examined the vaginal microbiome in two cohorts of women…”
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Microdiversity of the vaginal microbiome is associated with preterm birth
Published in Nature communications (17-08-2023)“…Preterm birth (PTB) is the leading cause of neonatal morbidity and mortality. The vaginal microbiome has been associated with PTB, yet the mechanisms…”
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The association of maternal factors with the neonatal microbiota and health
Published in Nature communications (19-06-2024)“…The human microbiome plays a crucial role in human health. However, the influence of maternal factors on the neonatal microbiota remains obscure. Herein, our…”
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Clostridium scindens: a human gut microbe with a high potential to convert glucocorticoids into androgens
Published in Journal of lipid research (01-09-2013)“…Clostridium scindens American Type Culture Collection 35704 is capable of converting primary bile acids to toxic secondary bile acids, as well as converting…”
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An emerging mycoplasma associated with trichomoniasis, vaginal infection and disease
Published in PloS one (22-10-2014)“…Humans are colonized by thousands of bacterial species, but it is difficult to assess the metabolic and pathogenic potential of the majority of these because…”
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Gut Colonization with Methanogenic Archaea Lowers Plasma Trimethylamine N-oxide Concentrations in Apolipoprotein e−/− Mice
Published in Scientific reports (03-10-2018)“…A mechanistic link between trimethylamine N-oxide (TMAO) and atherogenesis has been reported. TMAO is generated enzymatically in the liver by the oxidation of…”
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Effects of Combined Oral Contraceptives, Depot Medroxyprogesterone Acetate, and the Levonorgestrel-releasing Intrauterine System on the Vaginal Microbiome
Published in Contraception (Stoneham) (01-04-2017)“…Abstract Objectives Prior studies suggest that the composition of the vaginal microbiome may positively or negatively affect susceptibility to sexually…”
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Species-level classification of the vaginal microbiome
Published in BMC genomics (2012)“…The application of next-generation sequencing to the study of the vaginal microbiome is revealing the spectrum of microbial communities that inhabit the human…”
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Identification of a gene in Mycoplasma hominis associated with preterm birth and microbial burden in intraamniotic infection
Published in American journal of obstetrics and gynecology (01-06-2015)“…Objective Microbial invasion of the amniotic cavity is associated with spontaneous preterm labor and adverse pregnancy outcome, and Mycoplasma hominis often is…”
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Trypanosoma rangeli is phylogenetically closer to Old World trypanosomes than to Trypanosoma cruzi
Published in International journal for parasitology (01-06-2018)“…[Display omitted] •Trypanosoma rangeli and Trypanosoma cruzi are distant species convergently adapted to humans.•Trypanosoma rangeli is closely related to Old…”
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Genetic diversity of Trypanosoma cruzi in bats, and multilocus phylogenetic and phylogeographical analyses supporting Tcbat as an independent DTU (discrete typing unit)
Published in Acta tropica (01-11-2015)“…[Display omitted] •Multilocus phylogenetic analyses of 37 nuclear and 12 mitochondrial genes from Tcbat and strains of all DTUs corroborated Tcbat as an…”
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Biosynthesis of vitamins and cofactors in bacterium-harbouring trypanosomatids depends on the symbiotic association as revealed by genomic analyses
Published in PloS one (19-11-2013)“…Some non-pathogenic trypanosomatids maintain a mutualistic relationship with a betaproteobacterium of the Alcaligenaceae family. Intensive nutritional…”
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Genome-wide identification of evolutionarily conserved Small Heat-Shock and eight other proteins bearing α-crystallin domain-like in kinetoplastid protists
Published in PloS one (22-10-2018)“…Small Heat-Shock Proteins (sHSPs) and other proteins bearing alpha-crystallin domains (ACD) participate in defense against heat and oxidative stress and play…”
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Association between statin use, the vaginal microbiome, and Gardnerella vaginalis vaginolysin-mediated cytotoxicity
Published in PloS one (28-08-2017)“…Bacterial vaginosis (BV) is the leading dysbiosis of the vaginal microbiome. The pathways leading towards the development of BV are not well understood…”
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Impact of Herpes Simplex Virus Type 2 and Human Immunodeficiency Virus Dual Infection on Female Genital Tract Mucosal Immunity and the Vaginal Microbiome
Published in The Journal of infectious diseases (31-07-2019)“…Mechanisms linking herpes simplex virus type 2 (HSV-2) with human immunodeficiency virus (HIV) are not fully defined. We tested the hypothesis that HSV-2 and…”
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Endosymbiosis in trypanosomatids: the genomic cooperation between bacterium and host in the synthesis of essential amino acids is heavily influenced by multiple horizontal gene transfers
Published in BMC evolutionary biology (09-09-2013)“…Trypanosomatids of the genera Angomonas and Strigomonas live in a mutualistic association characterized by extensive metabolic cooperation with obligate…”
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Prevalence and incidence of sexually transmitted infections among South African women initiating injectable and long-acting contraceptives
Published in PloS one (10-11-2023)“…South Africa is among the countries with the highest prevalence of sexually transmitted infections (STIs), including Chlamydia trachomatis (CT) and Neisseria…”
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