Search Results - "Serrano, Juan C"

TET-TDG Active DNA Demethylation at CpG and Non-CpG Sites by DeNizio, Jamie E., Dow, Blaine J., Serrano, Juan C., Ghanty, Uday, Drohat, Alexander C., Kohli, Rahul M.

“…[Display omitted] •Systematic study of all possible TET/TDG substrates in CG or non-CG contexts.•Uncovers relative tolerance to CH contexts for hmC oxidation…”
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Modular cytokine receptor-targeting chimeras for targeted degradation of cell surface and extracellular proteins by Pance, Katarina, Gramespacher, Josef A., Byrnes, James R., Salangsang, Fernando, Serrano, Juan-Antonio C., Cotton, Adam D., Steri, Veronica, Wells, James A.

“…Targeted degradation of cell surface and extracellular proteins via lysosomal delivery is an important means to modulate extracellular biology. However, these…”
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Structure-Guided Design of a Potent and Specific Inhibitor against the Genomic Mutator APOBEC3A by Serrano, Juan C., von Trentini, Dora, Berríos, Kiara N., Barka, Aleksia, Dmochowski, Ivan J., Kohli, Rahul M.

“…Nucleic acid structure plays a critical role in governing the selectivity of DNA- and RNA-modifying enzymes. In the case of the APOBEC3 family of cytidine…”
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Cooperativity between Cas9 and hyperactive AID establishes broad and diversifying mutational footprints in base editors by Berríos, Kiara N, Barka, Aleksia, Gill, Jasleen, Serrano, Juan C, Bailer, Peter F, Parker, Jared B, Evitt, Niklaus H, Gajula, Kiran S, Shi, Junwei, Kohli, Rahul M

“…Abstract The partnership of DNA deaminase enzymes with CRISPR-Cas nucleases is now a well-established method to enable targeted genomic base editing. However,…”
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A New Methodology for Incorporating Chiral Linkers into Stapled Peptides by Serrano, Juan C., Sipthorp, James, Xu, Wenshu, Itzhaki, Laura S., Ley, Steven V.

“…Stapled peptides have arisen as a new class of chemical probe and potential therapeutic agents for modulating protein–protein interactions. Here, we report the…”
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Synthesis, antimalarial properties and 2D-QSAR studies of novel triazole-quinine conjugates by Faidallah, Hassan M., Panda, Siva S., Serrano, Juan C., Girgis, Adel S., Khan, Khalid A., Alamry, Khalid A., Therathanakorn, Tanya, Meyers, Marvin J., Sverdrup, Francis M., Eickhoff, Christopher S., Getchell, Stephen G., Katritzky, Alan R.

“…[Display omitted] •Designed and synthesized a set of triazole containing quinine conjugates.•Synthesized conjugates shows promising antimalarial…”
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Synthesis and antibacterial evaluation of amino acid–antibiotic conjugates by Ibrahim, Mohamed A., Panda, Siva S., Birs, Antoinette S., Serrano, Juan C., Gonzalez, Claudio F., Alamry, Khalid A., Katritzky, Alan R.

“…Amino acid conjugates of quinolone, metronidazole and sulfadiazine antibiotics were synthesized in good yields using benzotriazole methodology. All the…”
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Efficient Routes to a Diverse Array of Amino Alcohol-Derived Chiral Fragments by Haftchenary, Sina, Nelson, Shawn D, Furst, Laura, Dandapani, Sivaraman, Ferrara, Steven J, Bošković, Žarko V, Figueroa Lazú, Samuel, Guerrero, Adrian M, Serrano, Juan C, Crews, DeMarcus K, Brackeen, Cristina, Mowat, Jeffrey, Brumby, Thomas, Bauser, Marcus, Schreiber, Stuart L, Phillips, Andrew J

“…Efficient syntheses of chiral fragments derived from chiral amino alcohols are described. Several unique scaffolds were readily accessed in 1–5 synthetic steps…”
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Low velocity impact response of autoclaved aerated concrete/CFRP sandwich plates by Serrano-Perez, Juan C., Vaidya, Uday K., Uddin, Nasim

“…Autoclaved aerated concrete (AAC)-CFRP composites have proven to be structurally efficient combinations for lightweight structural components such as floor…”
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Epidemiology of childhood ocular trauma in a northeastern Colombian region by Serrano, Juan C, Chalela, Patricia, Arias, Juan D

“…To describe the epidemiology of ocular trauma in children 15 years and younger who underwent evaluation during a 5-year period in the emergency department of a…”
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Structural Characterization of Hybrid Fiber Reinforced Polymer (FRP)-Autoclave Aerated Concrete (AAC) Panels by Uddin, Nasim, Fouad, Fouad, Vaidya, Uday K., Khotpal, Amol, Serrano-Perez, Juan C.

“…The structural characterization of hybrid fiber reinforced polymer (FRP)-autoclaved aerated concrete (AAC) panels is examined in this study. The structural…”
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The effect of the cerium precursor and the carbon surface chemistry on the dispersion of ceria on activated carbon by Ramos-Fernández, Enrique V., Serrano-Ruiz, Juan C., Silvestre-Albero, Joaquín, Sepúlveda-Escribano, Antonio, Rodríguez-Reinoso, Francisco

“…Activated carbon-supported cerium dioxide (CeO 2 /C) was prepared by impregnation of a commercial support (Norit R2030) with aqueous solutions of two different…”
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Design and analysis of a long fiber thermoplastic composite tailcone for a tank gun training round by Vaidya, Uday K., Serrano, Juan C., Villalobos, Alejandro, Sands, James, Garner, James

“…The increasing demand for low cost composites in military applications is accompanied by the need to develop cost-effective and high-performance material forms…”
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Pediatric Glaucoma at Fundación Oftalmológica de Santander by Juan C. Serrano Camacho, Sandra Rocio Montezuma

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