Search Results - "Serrano, D S"

Role of tryptophan-74 of the recombinant kringle 2 domain of tissue-type plasminogen activator in its .omega.-amino acid binding properties by De Serrano, Vesna S, Castellino, Francis J

“…The role of W74 in stabilization of the binding of omega-amino acids to the recombinant (r) kringle 2 domain (residues 180-261) of tissue-type plasminogen…”
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Specific anionic residues of the recombinant kringle 2 domain of tissue-type plasminogen activator that are responsible for stabilization of its interaction with .omega.-amino acid ligands by De Serrano, Vesna S, Castellino, Francis J

“…The involvement of specific aspartic acid (D) and glutamic acid (E) residues of the recombinant (r) kringle 2 (K2) domain of tissue-type plasminogen activator…”
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The cationic locus on the recombinant kringle 2 domain of tissue-type plasminogen activator that stabilizes its interaction with .omega.-amino acids by De Serrano, Vesna S, Castellino, Francis J

“…The properties of the cationic locus within the recombinant (r) kringle 2 domain (residues 180-261) of tissue-type plasminogen activator ([K2tPA]) that are…”
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Role of the Strictly Conserved Tryptophan-25 Residue in the Stabilization of the Structure and in the Ligand Binding Properties of the Kringle 2 Domain of Tissue-Type Plasminogen Activator by De Serrano, Vesna S, Castellino, Francis J

“…The involvement of the strictly conserved tryptophan-25 (W25) residue in the structural stability and omega-amino acid ligand binding properties of the…”
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Involvement of Tyrosine-76 of the Kringle 2 Domain of Tissue-Type Plasminogen Activator in Its Thermal Stability and Its .omega.-Amino Acid Ligand Binding Site by De Serrano, Vesna S, Castellino, Francis J

“…A series of conservative and radical mutations have been made at an aromatic residue, Y76, of the isolated kringle 2 domain of tissue-type plasminogen…”
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Efficient Low-Temperature Oxidation of Carbon-Cluster Anions by SO2 by Leavitt, Andrew J, Wyrwas, Richard B, Wallace, William T, Serrano, Daniel S, Arredondo, Melissa G, Leslie, Logan M, Khan, Farooq A, Whetten, Robert L

“…Carbon-cluster anions, C N -, are very reactive toward SO2 (sticking probability of 0.012 ± 0.005 for C27 - at 25 °C), in contrast to their inertness toward…”
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Role of lipolytic enzymes in the development of hyperlipidemia induced by administration of heterologous albumin in rabbits by Serrano, D S, Nikul'cheva, N G, Soliternova, I B

“…Experiments on rabbits have shown hyperlipidemia to develop within the first 48 h after a single intravenous injection of bovine serum albumin (BSA, fraction…”
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Inhibition of lipoprotein lipolysis by polyarginine and evaluation of the mechanism of its interaction with lipoprotein lipase by Klimov, A N, Serrano, D S, Kliueva, N N, Soliternova, I B, Nikul'cheva, N G

“…It was found that polyarginine (Mr 40 000-60 000) is a strong inhibitor of the lipoprotein lipase activity in vivo and in vitro. The inhibitory effect in vivo…”
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Effect of the synthetic tetradecapeptide corresponding to the amino acid sequence of human somatotropin 31-44 on rat blood and liver lipids by Ryzhenkov, V E, Pankov, Iu A, Chistiakova, A M, Keda, Iu M, Serrano, D S

“…Although synthetic tetradecapeptide, involving the 31-44 amino acid sequence of human growth hormone, exhibited a distinct lipolytic effect, content of…”
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Comparison of the effect of homologous and heterologous albumin on the activity of lipoprotein lipase and liver triglyceride lipase in rabbit plasma by Klimov, A N, Serrano, D S, Nikul'cheva, N G, Soliternova, I B

“…Changes in the activity of blood plasma lipoprotein lipase (EC 3.1.1.34, LPL and hepatic triacylglycerol lipase EC 3.1.1.3, H-TGL) were studied in rabbits…”
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Effect of colchicine on heart lipoprotein lipase by Lavín-Palmieri, M, Sánchez Serrano, D

“…Changes in heart lipoprotein lipase (LPL) activity provoked by colchicine (0.5 mg/100 g body weight) and heparin (10 IU/100 g body weight) were studied in…”
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The activation of human [Glu1]plasminogen by human single-chain urokinase by Urano, T, de Serrano, V S, Gaffney, P J, Castellino, F J

“…The activation of human [Glu1]plasminogen ([Glu1]Pg) by single-chain human urokinase (SCUKase) displays a substantial lag phase at physiological levels of…”
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Structural determinants of the noncatalytic chain of tissue-type plasminogen activator that modulate its association rate with plasminogen activator inhibitor-1 by DE SERRANO, V. S, CASTELLINO, F. J

“…In order to identify the regions of recombinant (r) tissue plasminogen activator (tPA) that mediate its kinetically relevant interaction with r-plasminogen…”
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Role of lipolytic enzymes in the development of hyperlipidemia induced by heterologous albumin in rabbits by Serrano, D. Sanchez, Nikul'cheva, N. G., Soliternova, I. B.

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Stimulation by fibrinogen of the amidolytic activity of single-chain tissue plasminogen activator by Urano, T, deSerrano, V S, Urano, S, Castellino, F J

“…The amidolytic steady-state kinetic properties of a series of recombinant tissue plasminogen activators (rt-PA) have been examined in the presence and absence…”
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Appearance of plasminogen activator activity during a synchronous cycle of a rat adenocarcinoma cell line, PA-III by Scott, F M, Sator de Serrano, V, Castellino, F J

“…A study of the appearance of plasminogen activators during the cell cycle of a rat prostate adenocarcinoma cell line, PA-III, was undertaken. After release…”
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Roles for Chloride Ion and Fibrinogen in the Activation of [Glu1]Plasminogen in Human Plasma by Gaffney, Patrick J., Urano, Tetsumei, De Serrano, Vesna S., Mahmoud-Alexandroni, Maher, Metzger, Alan R., Castellino, Francis J.

“…Using two-dimensional immunoelectrophoresis and an antibody to α 2-antiplasmin, we assessed the plasmin generated in serum under different conditions as the…”
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Purification and properties of a plasminogen activator from cultured rat prostate adenocarcinoma cells by Strickland, Dudley K, Sator de Serrano, Vesna, Chan, Sham Yeun, Pollard, Morris, Castellino, Francis J

“…Zymographic analysis of the supernates from confluent cultures of a rat prostate adenocarcinoma cell line, PA-III, revealed the existence of two molecular…”
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Influence of various structural domains of fibrinogen and fibrin on the potentiation of plasminogen activation by recombinant tissue plasminogen activator by de Serrano, V S, Urano, T, Gaffney, P J, Castellino, F J

“…Fibrinogen, fibrin, and related fragments have varying stimulatory effects on the initial rate of the activation of human plasminogen ([ Glu1]Pg) by…”
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