Search Results - "Serra, Magda F."

Gold Nanoparticles Inhibit Steroid-Insensitive Asthma in Mice Preserving Histone Deacetylase 2 and NRF2 Pathways by Serra, Magda F., Cotias, Amanda C., Pimentel, Andreza S., Arantes, Ana Carolina S. de, Pires, Ana Lucia A., Lanzetti, Manuella, Hickmann, Jandir M., Barreto, Emiliano, Carvalho, Vinicius F., Silva, Patrícia M. R. e, Cordeiro, Renato S. B., Martins, Marco Aurélio

“…Background: Gold nanoparticles (AuNPs) can inhibit pivotal pathological changes in experimental asthma, but their effect on steroid-insensitive asthma is…”
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Diabetes Downregulates Allergen-Induced Airway Inflammation in Mice by Silva, Patrícia M. R. e, Martins, Marco A., Jannini-Sá, Yago A. P., Ferreira, Tatiana Paula T., Serra, Magda F., Arantes, Ana Carolina S., Barreto, Emiliano O., Carvalho, Vinicius F., Hogaboam, Cory M.

“…Previous studies described that allergic diseases, including asthma, occur less often than expected in patients with type 1 diabetes. Here, we investigated the…”
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Nebulized Lidocaine Prevents Airway Inflammation, Peribronchial Fibrosis, and Mucus Production in a Murine Model of Asthma by SERRA, Magda F, ANJOS-VALOTTA, Edna A, CORDEIRO, Renato S. B, SILVA, Patricia M. R, MARTINS, Marco A, OLSEN, Priscilla C, COUTO, Gina C, JURGILAS, Patricia B, COTIAS, Amanda C, PAO, Camila R, FERREIRA, Tatiana P. T, ARANTES, Ana C. S, PIRES, Ana L. A

“…Evidence suggests that nebulized lidocaine is beneficial in asthma therapy, but to what extent and the mechanisms underlying this effect remain poorly…”
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Repeated Allergen Exposure in A/J Mice Causes Steroid-Insensitive Asthma via a Defect in Glucocorticoid Receptor Bioavailability by Serra, Magda F, Cotias, Amanda C, Pão, Camila R R, Daleprane, Julio B, Jurgilas, Patricia B, Couto, Gina C, Anjos-Valotta, Edna A, Cordeiro, Renato S B, Carvalho, Vinicius F, Silva, Patricia M R, Martins, Marco A

“…The importance of developing new animal models to assess the pathogenesis of glucocorticoid (GC)-insensitive asthma has been stressed. Because of the…”
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JM25-1, a Lidocaine Analog Combining Airway Relaxant and Antiinflammatory Properties: Implications for New Bronchospasm Therapy by Serra, Magda F, Neves, Josiane S, Couto, Gina C, Cotias, Amanda C, Pão, Camila R, Olsen, Priscilla C, de Carvalho, Katharinne I Moraes, Anjos-Valotta, Edna A, Faria, Robson X, Costa, Jorge C S, Cordeiro, Renato S B, Silva, Patricia M R, Martins, Marco A

“…BACKGROUND:Inhaled lidocaine antagonized bronchospasm in animal models and patients, but adverse effects limited its efficacy. This study evaluated the…”
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Local anaesthetic medication for the treatment of asthma by Rodrigo A Siqueira, Jorge CS Costa, Renato SB Cordeiro, Magda F Serra, Patrícia MR, Silva, Marco A Martins

“…It is presumed that drugs able to prevent bronchial spasm and/or inflammation may have therapeutic potential to control asthma symptoms. The local anaesthetic…”
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Aldose reductase inhibitor zopolrestat restores allergic hyporesponsiveness in alloxan-diabetic rats by Carvalho, Vinicius F., Barreto, Emiliano O., Serra, Magda F., Cordeiro, Renato S.B., Martins, Marco A., Fortes, Zuleica Bruno, e Silva, Patrícia M.R.

“…This study was undertaken to investigate the role of the aldose reductase in the refractoriness of diabetic rats to allergic inflammation. Wistar rats were…”
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Cyclooxygenase-2-Derived Prostaglandin E2 and Lipoxin A4 Accelerate Resolution of Allergic Edema in Angiostrongylus costaricensis-Infected Rats: Relationship with Concurrent Eosinophilia by Bandeira-Melo, Christianne, Serra, Magda F, Diaz, Bruno L, Cordeiro, Renato S. B, Silva, Patricia M. R, Lenzi, Henrique L, Bakhle, Y. S, Serhan, Charles N, Martins, Marco A

“…In noninfected rats, challenge with allergen following local IgE sensitization induced a pleurisy marked by intense protein exudation that plateaued from 30…”
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Antigen-induced Pleural Eosinophilia Is Suppressed In Diabetic Rats: Role Of Corticosteroid Hormones by Diaz, Bruno L, Serra, Magda F, Barreto, Emiliano O, Cordeiro, Renato S.B, Martins, Marco A, E Silva, Patricia M.R

“…Previous studies have evidenced for the existence of interactive regulatory mechanisms between insulin and steroid hormones in different systems. In this…”
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Systemic anaphylaxis is prevented in alloxan-diabetic rats by a mechanism dependent on glucocorticoids by Carvalho, Vinicius F., Barreto, Emiliano O., Diaz, Bruno L., Serra, Magda F., Azevedo, Viviane, Cordeiro, Renato S.B., Martins, Marco A., e Silva, Patrı́cia M.R.

“…This study was undertaken to examine whether glucocorticoids could be implicated in the hyporesponsiveness of diabetic rats to systemic anaphylaxis. Rats were…”
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Modulation of eotaxin formation and eosinophil migration by selective inhibitors of phosphodiesterase type 4 isoenzyme by Silva, Patrícia M R, Alves, Alessandra C, Serra, Magda F, Pires, Ana Lucia A, Silva, Juliane P, Barreto, Emiliano O, Cordeiro, Renato S B, Jose, Peter J, Teixeira, Mauro M, Lagente, Vincent, Martins, Marco A

“…This study was undertaken to investigate the possible contribution of the blockade of eotaxin generation to the anti‐eosinophilotactic effect of…”
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Selective inhibition of phosphodiesterase type IV suppresses the chemotactic responsiveness of rat eosinophils in vitro by Alves, Alessandra C., Pires, Ana L.A., Cruz, Hermenegildo N., Serra, Magda F., Diaz, Bruno L., Cordeiro, Renato S.B., Lagente, Vincent, Martins, Marco A., e Silva, Patrícia M.R.

“…Previous studies demonstrated that the selective inhibition of phosphodiesterase type IV suppresses antigen-induced eosinophil infiltration and also…”
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JM25-1, a Lidocaine Analog Combining Airway Relaxant and Antiinflammatory Properties by Serra, Magda F., Neves, Josiane S., Couto, Gina C., Cotias, Amanda C., Pão, Camila R., Olsen, Priscilla C., de Carvalho, Katharinne I. Moraes, Anjos-Valotta, Edna A., Faria, Robson X., Costa, Jorge C. S., Cordeiro, Renato S. B., Silva, Patricia M. R., Martins, Marco A.

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Anti-allergic properties of the natural PAF antagonist yangambin by Serra, M F, Diaz, B L, Barreto, E O, Pereira, A P, Lima, M C, Barbosa-Filho, J M, Cordeiro, R S, Martins, M A, de Silva, P M

“…In this study we examined the ability of the furofuran lignan yangambin to influence the local and systemic responses induced by antigen or PAF in actively…”
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Local exposure to salbutamol or Bt 2 cyclic AMP inhibits pleural exudation and leukocyte influx caused by antigen in rats by Diaz, Bruno L., Serra, Magda F., Alves, Alessandra C., Cordeiro, Renato S.B., Martins, Marco A., e Silva, Patricia M.R.

“…The local effect of salbutamol and N 6,2′- O-dibutyryl adenosine 3′:5′-cyclic monophosphate (Bt 2 cyclic AMP) on the rat pleural inflammation caused by…”
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Local exposure to salbutamol or Bt2 cyclic AMP inhibits pleural exudation and leukocyte influx caused by antigen in rats by Diaz, B L, Serra, M F, Alves, A C, Cordeiro, S B, Martins, M A, e Silva, P M

“…The local effect of salbutamol and N6,2'-O-dibutyryl adenosine 3':5'-cyclic monophosphate (Bt2 cyclic AMP) on the rat pleural inflammation caused by allergen…”
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