Search Results - "Serpe, Loredana"

Biomedical Applications of Reactive Oxygen Species Generation by Metal Nanoparticles by Canaparo, Roberto, Foglietta, Federica, Limongi, Tania, Serpe, Loredana

“…The design, synthesis and characterization of new nanomaterials represents one of the most dynamic and transversal aspects of nanotechnology applications in…”
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Methodological aspects and pharmacological applications of three-dimensional cancer cell cultures and organoids by Foglietta, Federica, Canaparo, Roberto, Muccioli, Giampiero, Terreno, Enzo, Serpe, Loredana

“…Two-dimensional (2D) cell cultures, in which cells grow in flat layers on plastic surfaces, are considered the standard model for use in drug screening and for…”
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Recent Developments in Antibacterial Therapy: Focus on Stimuli-Responsive Drug-Delivery Systems and Therapeutic Nanoparticles by Canaparo, Roberto, Foglietta, Federica, Giuntini, Francesca, Della Pepa, Carlo, Dosio, Franco, Serpe, Loredana

“…Conventional drugs used for antibacterial therapy display several limitations. This is not due to antibiotics being ineffective, but rather due to their low…”
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ROS-generating nanoplatforms as selective and tunable therapeutic weapons against cancer by Foglietta, Federica, Serpe, Loredana, Canaparo, Roberto

“…Reactive species refers to a group of chemicals, mainly reactive oxygen species (ROS) and reactive nitrogen species (RNS), that are naturally formed by cells…”
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Cyclodextrin-based nanosponges encapsulating camptothecin: Physicochemical characterization, stability and cytotoxicity by Swaminathan, Shankar, Pastero, Linda, Serpe, Loredana, Trotta, Francesco, Vavia, Pradeep, Aquilano, Dino, Trotta, Michele, Zara, GianPaolo, Cavalli, Roberta

“…Camptothecin (CAM), a plant alkaloid and a potent antitumor agent, has a limited therapeutic utility because of its poor aqueous solubility, lactone ring…”
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The Effective Combination between 3D Cancer Models and Stimuli-Responsive Nanoscale Drug Delivery Systems by Foglietta, Federica, Serpe, Loredana, Canaparo, Roberto

“…Stimuli-responsive drug-delivery systems (DDSs) have emerged as a potential tool for applications in healthcare, mainly in the treatment of cancer where…”
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Early impact of donor CYP3A5 genotype and Graft-to-Recipient Weight Ratio on tacrolimus pharmacokinetics in pediatric liver transplant patients by Pinon, Michele, De Nicolò, Amedeo, Pizzol, Antonio, Antonucci, Miriam, D’Avolio, Antonio, Serpe, Loredana, Dell’Olio, Dominic, Catalano, Silvia, Tandoi, Francesco, Romagnoli, Renato, Canaparo, Roberto, Calvo, Pier Luigi

“…Tacrolimus (TAC) pharmacokinetics is influenced by the donor CYP3A5 genotype and the age of pediatric liver recipients. However, an optimization of a…”
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Pharmacological Inhibition of NLRP3 Inflammasome Attenuates Myocardial Ischemia/Reperfusion Injury by Activation of RISK and Mitochondrial Pathways by Bertinaria, Massimo, Pagliaro, Pasquale, Aragno, Manuela, Collino, Massimo, Cocco, Mattia, Alloatti, Giuseppe, Collotta, Debora, Serpe, Loredana, Chiazza, Fausto, Nigro, Debora, Penna, Claudia, Tullio, Francesca, Femminò, Saveria, Mastrocola, Raffaella

“…Although the nucleotide-binding oligomerization domain- (NOD-) like receptor pyrin domain containing 3 (NLRP3) inflammasome has been recently detected in the…”
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Solid lipid nanoparticles delivering anti-inflammatory drugs to treat inflammatory bowel disease: Effects in an in vivo model by Dianzani, Chiara, Foglietta, Federica, Ferrara, Benedetta, Rosa, Arianna Carolina, Muntoni, Elisabetta, Gasco, Paolo, Della Pepa, Carlo, Canaparo, Roberto, Serpe, Loredana

“…AIM To improve anti-inflammatory activity while reducing drug doses, we developed a nanoformulation carrying dexamethasone and butyrate.METHODS Dexamethasone…”
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Ultrasound Triggers Hypericin Activation Leading to Multifaceted Anticancer Activity by Foglietta, Federica, Canaparo, Roberto, Cossari, Simone, Panzanelli, Patrizia, Dosio, Franco, Serpe, Loredana

“…The use of ultrasound (US) in combination with a responsive chemical agent (sonosensitizer) can selectively trigger the agent's anticancer activity in a…”
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Biological Effect Evaluation of Glutathione-Responsive Cyclodextrin-Based Nanosponges: 2D and 3D Studies by Argenziano, Monica, Foglietta, Federica, Canaparo, Roberto, Spagnolo, Rita, Della Pepa, Carlo, Caldera, Fabrizio, Trotta, Francesco, Serpe, Loredana, Cavalli, Roberta

“…This study aims to evaluate the bioeffects of glutathione-responsive β-cyclodextrin-based nanosponges (GSH-NSs) on two- (2D) and three-dimensional (3D) cell…”
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Exploiting Shock Waves to Trigger the Anticancer Sonodynamic Activity of 5-Aminolevulinc Acid-Derived Protoporphyrin IX on In Vitro 2D and 3D Cancer Models by Foglietta, Federica, Panzanelli, Patrizia, Serpe, Loredana, Canaparo, Roberto

“…Sonodynamic therapy (SDT) is a noninvasive method for cancer treatment based on selective activation of a sonosensitiser by ultrasound (US), which results in…”
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Chronic administration of saturated fats and fructose differently affect SREBP activity resulting in different modulation of Nrf2 and Nlrp3 inflammasome pathways in mice liver by Nigro, Debora, Menotti, Francesca, Cento, Alessia S., Serpe, Loredana, Chiazza, Fausto, Dal Bello, Federica, Romaniello, Francesco, Medana, Claudio, Collino, Massimo, Aragno, Manuela, Mastrocola, Raffaella

“…The overconsumption of both saturated fats and fructose in the modern society has been related to the development of nonalcoholic fatty liver disease (NAFLD)…”
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Editorial: The Role of Reactive Oxygen Species in Chemical and Biochemical Processes by Vitiello, Giuseppe, Serpe, Loredana, Blázquez-Castro, Alfonso

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Engineered porphyrin loaded core-shell nanoparticles for selective sonodynamic anticancer treatment by Varchi, Greta, Foglietta, Federica, Canaparo, Roberto, Ballestri, Marco, Arena, Francesca, Sotgiu, Giovanna, Guerrini, Andrea, Nanni, Cristina, Cicoria, Gianfranco, Cravotto, Giancarlo, Fanti, Stefano, Serpe, Loredana

“…Porphyrin-loaded core-shell nanoparticles have been engineered for use as sonosensitizing systems, radio-tracers or magnetic resonance (MR) imaging agents,…”
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Nanosonotechnology: the next challenge in cancer sonodynamic therapy by Serpe Loredana, Foglietta Federica, Canaparo Roberto

“…Sonodynamic therapy (SDT) is a newly developed anticancer treatment where ultrasound is used to trigger the cytotoxic effect of chemical compounds, known as…”
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Food Bioactive Compounds and Their Interference in Drug Pharmacokinetic/Pharmacodynamic Profiles by Briguglio, Matteo, Hrelia, Silvana, Malaguti, Marco, Serpe, Loredana, Canaparo, Roberto, Dell'Osso, Bernardo, Galentino, Roberta, De Michele, Sara, Dina, Carlotta Zanaboni, Porta, Mauro, Banfi, Giuseppe

“…Preclinical and clinical studies suggest that many food molecules could interact with drug transporters and metabolizing enzymes through different mechanisms,…”
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Development of ARPE-19-Equipped Ocular Cell Model for In Vitro Investigation on Ophthalmic Formulations by Sapino, Simona, Chindamo, Giulia, Peira, Elena, Chirio, Daniela, Foglietta, Federica, Serpe, Loredana, Vizio, Barbara, Gallarate, Marina

“…Repeated intravitreal (IVT) injections in the treatment of retinal diseases can lead to severe complications. Developing innovative drug delivery systems for…”
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Effects of the Molecular Weight of Hyaluronic Acid in a Carbon Nanotube Drug Delivery Conjugate by Arpicco, Silvia, Bartkowski, Michał, Barge, Alessandro, Zonari, Daniele, Serpe, Loredana, Milla, Paola, Dosio, Franco, Stella, Barbara, Giordani, Silvia

“…Hyaluronic acid (HA) is a ubiquitous biopolymer involved in many pathophysiological roles. One HA receptor, the cluster of differentiation CD44 protein, is…”
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5-Aminolevulinic Acid Triggered by Ultrasound Halts Tumor Proliferation in a Syngeneic Model of Breast Cancer by Foglietta, Federica, Gola, Giulia, Biasibetti, Elena, Capucchio, Maria Teresa, Bruni, Iside, Francovich, Andrea, Durando, Gianni, Serpe, Loredana, Canaparo, Roberto

“…Sonodynamic therapy is a bimodal therapeutic approach in which a chemical compound and ultrasound (US) synergistically act to elicit oxidative damage,…”
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