Search Results - "Serova, O. V."

A Comparative Kidney Transcriptome Analysis of Bicarbonate-Loaded insrr -Null Mice by Gantsova, E A, Serova, O V, Eladari, D, Bobrovskiy, D M, Petrenko, A G, Elchaninov, A V, Deyev, I E

“…The maintenance of plasma pH is critical for life in all organisms. The kidney plays a critical role in acid-base regulation in vertebrates by controlling the…”
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Interaction between Endocrine and Exocrine Pancreas by Mostafa, A., Gantsova, E. A., Serova, O. V., Mohammad, T., Deyev, I. E.

“…The pancreas plays a key role in the endocrine system of animals, as well as in the digestion and absorption of nutrients. The exocrine and endocrine portions…”
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The Value of pH Sensors in Maintaining Homeostasis of the Nervous System by Serova, O. V., Gantsova, E. A., Deyev, I. E., Petrenko, A. G.

“…— Maintaining pH homeostasis is vital for all mammalian cells since hydrogen and hydroxyl ions perform important functions in the regulation of metabolism…”
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Changes in the Expression of the gapdh Gene in the Organs of insrr Knockout Mice by Gantsova, E. A., Gavrilenkova, A. A., Serova, O. V., Deyev, I. E.

“…— The most important property of a living organism is the maintenance of optimal acid–base balance and the ionic composition of the internal environment. The…”
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Tissue-Specific Expression of Neurexin-1α Isoforms in Rat Organs by Serova, O. V., Gantsova, E. A., Deyev, I. E., Petrenko, A. G.

“…— Neurexins are a family of synaptic adhesion proteins that play a key role in synapse formation and maintenance. Neurexins undergo extensive alternative…”
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Analysis of the Development of insrr Knockout Mouse Preimplantation Embryos by Gantsova, E. A., Deyev, I. E., Petrenko, A. G., Serova, O. V.

“…Maintaining an optimal acid-base balance of the organism has a pivotal role in the regulation of metabolism. It is provided by the functioning of endogenous…”
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Evidence of Selective Interaction of Nerve Growth Factor Dipeptide Mimetic GK-2 with TrkA Receptor Using TrkA and TrkB Knockout HT-22 Cells by Antipova, T. A., Deev, I. E., Gudasheva, T. A., Nikolaev, S. V., Logvinov, I. O., Serova, O. V., Gavrilenkova, A. A., Povarnina, P. Yu, Tarasiuk, A. V., Vakhitova, Yu. V., Seredenin, S. B.

“…TrkA and TrkB knockout HT-22 cell lines were used to prove that the neuroprotective properties of GK-2 [ bis ( N -monosuccinyl- L -glutamyl- L -lysine…”
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Generation and Characteristics of Genetically Encoded Fluorescent Sensors of Extracellular pH by Orsa, A. N., Goryashchenko, A. S., Serova, O. V., Mozhaev, A. A., Martynov, V. I., Pakhomov, A. A., Svirshchevskaya, E. V., Petrenko, A. G., Deyev, I. E.

“…— Recently, fluorescent proteins have become an indispensable tool for in vivo visualization of various processes occurring in living systems, from individual…”
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Impact of Residue R65 on the Stabilization of TEM-Type β-Lactamases with Substitution of M182T by Grigorenko, V. G., Andreeva, I. P., Serova, O. V., Rubtsova, M. Yu, Egorov, A. M.

“…For the experimental study of the role of the R65 residue in the stabilization of β-lactamases with the substitution of M182T, predicted by the analysis of the…”
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Effect of the Deletion of the (173–280) Fragment of the Inserted α-Helical Domain on the Functional Properties of АТР-Dependent Lon Protease from E. coli by Kudzhaev, A. M., Dubovtseva, E. S., Serova, O. V., Andrianova, A. G., Rotanova, T. V.

“…The effect of the coiled-coil ( CC ) region of the α-helical inserted domain of Escherichia coli Lon protease (Ec-Lon) on the functional activity of the enzyme…”
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The Hybrid Protein of the Alkaline Sensor IRR and the Fluorescent Protein GFP Retains the Functional Activity of the Receptor by Mozhaev, A. A., Serova, O. V., Orsa, A. N., Boyko, A. A., Goryashchenko, A. S., Deyev, I. E., Petrenko, A. G.

“…— The insulin receptor-related receptor (IRR) is a cellular sensor of a weakly alkaline medium. Its spatial structure and the mechanism of activation have not…”
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Production and immunochemical characterization of monoclonal antibody to IRR ectodomain by Mozhaev, A. A., Erokhina, T. N., Serova, O. V., Deyev, I. E., Petrenko, A. G.

“…The insulin receptor-related receptor (IRR) is the only known metabotropic sensor of extracellular alkaline medium involved in the regulation of the acid–base…”
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Role of the Inserted α-Helical Domain in E. coli ATP-Dependent Lon Protease Function by Kudzhaev, A M, Andrianova, A G, Dubovtseva, E S, Serova, O V, Rotanova, T V

“…Multidomain ATP-dependent Lon protease of (Ec-Lon) is one of the key enzymes of the quality control system of the cellular proteome. A recombinant form of…”
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Influence of the (1–106) fragment of Escherichia coli Lon protease on the enzyme function and DNA binding by Kudzhaev, A. M., Dubovtseva, E. S., Serova, O. V., Andrianova, A. G., Rotanova, T. V.

“…Bifunctional Escherichia coli LonA protease (Ec-Lon) belongs to the superfamily of AAA + proteins. It is a key member of the quality control system of the cell…”
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Immunogenic and Protective Properties of Neisseria meningitidis IgA1 Protease and of Its Truncated Fragments by Zinchenko, A. A., Kotelnikova, O. V., Gordeeva, E. A., Prokopenko, Yu. A., Razgulyaeva, O. A., Serova, O. V., Melikhova, T. D., Nokel, E. A., Zhigis, L. S., Zueva, V. S., Alliluev, A. P., Rumsh, L. D.

“…Four recombinant proteins, MA 28 –P 1004 LEH 6 , ME 135 –H 328 LEH 6 , MW 329 –H 622 LEH 6 and MH 835 –P 1004 LEH 6 , were prepared based on the genomic…”
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Serological Analysis of Immunogenic Properties of Recombinant Meningococcus IgA1 Protease-Based Proteins by Kotelnikova, O. V., Zinchenko, A. A., Vikhrov, A. A., Alliluev, A. P., Serova, O. V., Gordeeva, E. A., Zhigis, L. S., Zueva, V. S., Razgulyaeva, O. A., Melikhova, T. D., Nokel, E. A., Drozhzhina, E. Yu, Rumsh, L. D.

“…Using the genome sequence of IgA1 protease of N. meningitidis of serogroup B, four recombinant proteins of different structure and molecular weight were…”
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Role of α-helical domains in functioning of ATP-dependent Lon protease of Escherichia coli by Andrianova, A. G., Kudzhaev, A. M., Serova, O. V., Dergousova, N. I., Rotanova, T. V.

“…Homooligomeric ATP-dependent LonA proteases are bifunctional enzymes belonging to the superfamily of AAA + proteins. Their subunits are formed by five…”
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Structural and functional analyses of the sixth site of neurexin alternative splicing by Serova, O. V., Radionov, N. V., Shayahmetova, D. M., Deyev, I. E., Petrenko, A. G.

“…In this study, we found the sixth site of alternative splicing (SS6) of neurexin 1a from the rat brain. This site is located between the fifth LNS and the…”
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Deficient Response to Experimentally Induced Alkalosis in Mice with the Inactivated insrr Gene by Deyev, I E, Rzhevsky, D I, Berchatova, A A, Serova, O V, Popova, N V, Murashev, A N, Petrenko, A G

“…Currently, the molecular mechanisms of the acid-base equilibrium maintenance in the body remain poorly understood. The development of alkalosis under various…”
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Protective properties of recombinant IgA1 protease from meningococcus by Kotel’nikova, O. V., Alliluev, A. P., Drozhzhina, E. Yu, Koroleva, I. S., Sitnikova, E. A., Zinchenko, A. A., Gordeeva, E. A., Melikhova, T. D., Nokel, E. A., Zhigis, L. S., Zueva, V. S., Razgulyaeva, O. A., Serova, O. V., Yagudaeva, E. Yu, Rumsh, L. D.

“…The study of enzymatic and protective properties of recombinant IgA1 protease in active and mutant form has shown that the active form of IgA1 protease…”
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