Search Results - "Serkova, T P"
-
1
Wave-Like Dose-Dependence of the Stimulating Effects of Dimebon on Cognition in a Wide Dose Range
Published in Bulletin of experimental biology and medicine (01-10-2019)“…Comparison of the cognition-stimulating effects of Dimebon in a wide dose range revealed a non-monotonic and nontrivial wave-like dose-dependence of its…”
Get full text
Journal Article -
2
Effect of Corticotropin-Like Intermediate Lobe Peptide on Presynaptic and Postsynaptic Glutamate Receptors and Postsynaptic GABA Receptors in Rat Brain
Published in Bulletin of experimental biology and medicine (01-03-2009)“…We studied the effect of corticotropin-like intermediate lobe peptide (CLIP) on presynaptic NMDA receptors and postsynaptic GABA, NMDA, and AMPA receptors in…”
Get full text
Journal Article -
3
Biological Activity of Spirocyclic Hydroxamic Acids
Published in Bulletin of experimental biology and medicine (01-12-2016)“…Iron-chelating activity of synthesized spirocyclic hydroxamic acids, their toxicity, and effects on mitochondrial function were studied using primary culture…”
Get full text
Journal Article -
4
N,N’-Substituted Selenoureas as Polyfunctional Antioxidants
Published in Bulletin of experimental biology and medicine (2016)“…Analysis of antioxidant activity of synthesized selenourea derivatives showed that N,N’-substituted selenoureas inhibited Fe(III)-induced LPO in rat brain…”
Get full text
Journal Article -
5
Dimebon improves learning in animals with experimental Alzheimer's disease
Published in Bulletin of experimental biology and medicine (01-06-2000)“…Systemic administration of antihistamine drug dimebon improves active avoidance conditioning in rats with chronic partial deprivation of cerebral cholinergic…”
Get full text
Journal Article -
6
Effect of Somatostatin on Presynaptic and Postsynaptic Glutamate Receptors and Postsynaptic GABA Receptors in the Neurons of Rat Brain
Published in Bulletin of experimental biology and medicine (01-11-2012)“…We studied the effect of somatostatin on presinaptic NMDA receptors and postsinaptic GABA, NMDA, and AMPA receptors in rat brain. It was shown that…”
Get full text
Journal Article -
7
Dimebon and tacrine inhibit neurotoxic action of beta-amyloid in culture and block L-type Ca(2+) channels
Published in Bulletin of experimental biology and medicine (01-11-2001)“…Dimebon, a Russian-made drug, inhibited toxic effects of beta -amyloid on cultured neurons. Excessive accumulation of beta-amyloid in the brain is…”
Get full text
Journal Article -
8
The effect of dithiocarbamates on neurotoxic action of 1-methyl-4-phenyl-1,2,3,6 tetrahydropyridine (MPTP) and on mitochondrial respiration chain
Published in Neurotoxicology (Park Forest South) (1996)“…The neurotoxin MPTP induces in human and in some laboratory animals parkinsonism-like neurological disorder, biochemically characterized by selective and…”
Get more information
Journal Article -
9
Comparison of the effect of NT-0409 and antidementia drugs on learning and memory in rats with chronic cerebral cholinergic deficiency
Published in Bulletin of experimental biology and medicine (01-01-2003)“…Systemic oral administration of NT-0409, a new synthetic agonist of AMPA subtype glutamate receptor, to rats with chronic partial AF64A-induced deprivation of…”
Get full text
Journal Article -
10
Autoantibodies to beta-amyloid and neurotransmitters in patients with Alzheimer's disease and senile dementia of the Alzheimer type
Published in Bulletin of experimental biology and medicine (01-02-2001)“…The content of autoantibodies to beta-amyloid protein Abeta(1-42), its neurotoxic fragment Abeta(25-35), and neurotransmitters were studied in the blood of…”
Get full text
Journal Article -
11
Effects of 17 beta-estradiol and its isomer 17 alpha-estradiol on learning in rats with chronic cholinergic deficiency in the brain
Published in Bulletin of experimental biology and medicine (01-05-2000)“…It was shown for the first time that estrogens 17 beta- and 17 alpha-estradiols compensate impaired cognitive functions in rats with partial chronic…”
Get full text
Journal Article -
12
Effects of delta sleep-inducing peptide on pre- and postsynaptic glutamate and postsynaptic GABA receptors in neurons of the cortex, hippocampus, and cerebellum in rats
Published in Bulletin of experimental biology and medicine (01-08-2006)“…We studied the effect of delta sleep-inducing peptide on GABA receptors of hippocampal and cerebellar neurons in rats. It was shown that delta sleep-inducing…”
Get full text
Journal Article -
13
Content of autoantibodies to bradykinin and beta-amyloid(1-42) as a criterion for biochemical differences between Alzheimer's dementias
Published in Bulletin of experimental biology and medicine (01-07-2003)“…We measured serum content of autoantibodies to beta-amyloid protein Abeta(1-42), its neurotoxic fragment Abeta(25-35), vasopressin, bradykinin, thrombin,…”
Get full text
Journal Article -
14
-
15
Ability of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine and some other pyridine derivatives to cause parkinsonism
Published in Bulletin of experimental biology and medicine (01-06-1989)Get full text
Journal Article -
16
Dimebon and Tacrine Inhibit Neurotoxic Action of [beta]-Amyloid in Culture and Block L-type Ca2+ Channels
Published in Bulletin of experimental biology and medicine (01-11-2001)“…Dimebon, a Russian-made drug, inhibited toxic effects of beta -amyloid on cultured neurons. Excessive accumulation of beta-amyloid in the brain is…”
Get full text
Journal Article -
17
Content of Autoantibodies to Bradykinin and [beta]-Amyloid1-42 as a Criterion for Biochemical Differences between Alzheimer's Dementias
Published in Bulletin of experimental biology and medicine (01-07-2003)“…We measured serum content of autoantibodies to beta-amyloid protein Abeta(1-42), its neurotoxic fragment Abeta(25-35), vasopressin, bradykinin, thrombin,…”
Get full text
Journal Article -
18
Autoantibodies to [beta]-Amyloid and Neurotransmitters in Patients with Alzheimer's Disease and Senile Dementia of the Alzheimer Type
Published in Bulletin of experimental biology and medicine (01-02-2001)“…The content of autoantibodies to beta-amyloid protein Abeta(1-42), its neurotoxic fragment Abeta(25-35), and neurotransmitters were studied in the blood of…”
Get full text
Journal Article -
19
Effects of 17[beta]-estradiol and its isomer 17[alpha]-estradiol on learning in rats with chronic cholinergic deficiency in the brain
Published in Bulletin of experimental biology and medicine (01-05-2000)“…It was shown for the first time that estrogens 17β- and 17α-estradiols compensate impaired cognitive functions in rats with partial chronic deprivation of…”
Get full text
Journal Article -
20