Search Results - "Serizawa, Nobufusa"

Molecular Design, Synthesis, and Hypoglycemic Activity of a Series of Thiazolidine-2,4-diones by Oguchi, Minoru, Wada, Kunio, Honma, Hidehito, Tanaka, Asako, Kaneko, Tomoko, Sakakibara, Sachiko, Ohsumi, Jun, Serizawa, Nobufusa, Fujiwara, Toshihiko, Horikoshi, Hiroyoshi, Fujita, Takashi

“…A series of imidazopyridine thiazolidine-2,4-diones were designed and synthesized from their corresponding pyridines. These compounds represent…”
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A novel murine anti-human Fas mAb which mitigates lymphadenopathy without hepatotoxicity by Ichikawa, Kimihisa, Yoshida-Kato, Hiroko, Ohtsuki, Masahiko, Ohsumi, Jun, Yamaguchi, Junko, Takahashi, Shu, Tani, Yoshiro, Watanabe, Mayumi, Shiraishi, Akio, Nishioka, Kusuki, Yonehara, Shin, Serizawa, Nobufusa

“…Defects in Fas-mediated apoptosis are implicated in autoimmune diseases including rheumatoid arthritis (RA). Although induction of Fas-mediated apoptosis could…”
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Cloning, characterization and expression of the gene encoding cytochrome P-450sca-in2 from Streptomyces carbophilus involved in production of pravastatin, a specific HMG-CoA reductase inhibitor by Watanabe, Ichiro, Nara, Futoshi, Serizawa, Nobufusa

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Humanization of the Mouse Anti-Fas Antibody HFE7A and Crystal Structure of the Humanized HFE7A Fab Fragment by Haruyama, Hideyuki, Ito, Shuichiro, Miyadai, Kenji, Takahashi, Tohru, Kawaida, Reimi, Takayama, Tomoko, Hanzawa, Hiroyuki, Hata, Tadashi, Yamaguchi, Junko, Yoshida-Kato, Hiroko, Ichikawa, Kimihisa, Ohsumi, Jun, Yonehara, Shin, Serizawa, Nobufusa

“…Binding of Fas ligand to Fas induces apoptosis. The Fas–Fas ligand system plays important roles in many biological processes, including the elimination of…”
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High-level secretory production of phospholipase A1 by Saccharomyces cerevisiae and Aspergillus oryzae by Shiba, Y. (Sankyo Co. Ltd., Iwaki, Fukushima (Japan). Biomedical Research Labs.), Ono, C, Fukui, F, Watanabe, I, Serizawa, N, Gomi, K, Yoshikawa, H

“…Phospholipase A 1 (PLA 1 ) is a hydrolytic enzyme that catalyzes the removal of the acyl group from position 1 of lecithin to form lysolecithin. The PLA 1…”
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Crystal Structure of the Antigen-Binding Fragment of Apoptosis-Inducing Mouse Anti-Human Fas Monoclonal Antibody HFE7A by Ito, Shuichiro, Takayama, Tomoko, Hanzawa, Hiroyuki, Ichikawa, Kimihisa, Ohsumi, Jun, Serizawa, Nobufusa, Hata, Tadashi, Haruyama, Hideyuki

“…Binding of Fas ligand to Fas induces apoptosis. The Fas-Fas ligand system plays important roles in many biological processes, including the elimination of…”
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Cloning and Characterization of a Novel Oxidoreductase KDRF from a Human Bone Marrow-derived Stromal Cell Line KM-102 by Koishi, Ryuta, Kawashima, Ichiro, Yoshimura, Chigusa, Sugawara, Mie, Serizawa, Nobufusa

“…A cDNA clone coding for a novel oxidoreductase was cloned from a human bone marrow-derived stromal cell line KM-102. We screened a cDNA library constructed…”
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Identification of a sequential B-cell epitope on major allergen (Cry j 1) of Japanese cedar (Cryptomeria japonica) pollen in mice by Tamura, Y, Sasaki, R, Inouye, S, Kawaguchi, J, Serizawa, N, Toda, M, Takemori, T, Sakaguchi, M

“…Japanese cedar (Cryptomeria japonica; CJ) pollinosis is one of the most common allergic diseases in Japan. B cell epitopes on Cry j 1, a major allergen of CJ…”
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Production of functional human selenocysteine-containing KDRF/thioredoxin reductase in E. coli by Koishi, R, Nakamura, T, Takazawa, T, Yoshimura, C, Serizawa, N

“…In a previous study, we reported the isolation of a cDNA encoding KDRF (KM-102-derived reductase like factor) from the human bone marrow-derived stromal cell…”
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Cloning and Expression of a Novel Murine Anti-human Fas Antibody by YOSHIDA-KATO, Hiroko, ICHIKAWA, Kimihisa, YAMAGUCHI, Junko, WATANABE, Kenji, OHSUMI, Jun, YONEHARA, Shin, SERIZAWA, Nobufusa

“…Agonistic anti-human Fas antibodies that can induce apoptosis are thought to have therapeutic effects for various diseases resulting from an abnormality of the…”
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Isolation and Characterization of the Gene Conferring Thiamine-inducible Expression from Saccharomyces cerevisiae by SHIBA, Yoichiro, ONO, Chiho, ICHIKAWA, Kimihisa, SERIZAWA, Nobufusa, YOSHIKAWA, Hiroji

“…The production level of CPY in Saccharomyces cerevisiae KS58-2D/pCY303 was drastically decreased when thiamine was not added to the culture medium. We isolated…”
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Crystallization and preliminary x-ray studies of the Fab fragment from a humanized version of the mouse anti-human fas antibody HFE7a by Ito, Shuichiro, Takayama, Tomoko, Hanzawa, Hiroyuki, Takahashi, Tohru, Miyadai, Kenji, Serizawa, Nobufusa, Haruyama, Hideyuki, Hata, Tadashi

“…A humanized version of the apoptosis-inducing mouse anti-human Fas monoclonal antibody, HFE7A, is under further development for the treatment of autoimmune…”
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Direct Formation of Human Interleukin-11 by Cis-Acting System of Plant Virus Protease in Escherichia coli by TAKAHASHI, Tohru, NAKANISHI, Michiko, YAO, Yoshio, UYEDA, Ichiro, SERIZAWA, Nobufusa

“…To produce a large amount of recombinant proteins in Escherichia coli, we constructed a unique cis-acting expression system using a plant virus protease. This…”
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Fermentative Production of trans-4-Hydroxy-L-proline by Clonostachys cylindrospora by Serizawa, Nobufusa, Matsuoka, Tatsuji, Hosoya, Tsuyoshi, Furuya, Kouhei

“…Studies were done on fermentative production of hydroxyproline, a useful chiral source of the side chain moiety of carbapenems. Various microorganisms were…”
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Thiamine Increases Expression of Yeast Gene by Ichikawa, Kimihisa, Shiba, Yoichiro, Yamazaki, Mitsuo, Serizawa, Nobufusa

“…We found that CPY production in Saccharomyces cerevisiae KS58-2D/pCY303 was increased by the addition of thiamine into the medium, while the addition of…”
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Fermentative Production of cis-4-Hydroxy-(l)-proline by Helicocerus oryzae and Acrocylindrium oryzae by Matsuoka, Tatsuji, Furuya, Kouhei, Serizawa, Nobufusa

“…The production of hydroxyproline by microorganisms was studied to discover the chiral source of the side chain moiety of carbapenem. cis-4-Hydroxy-(l)-proline…”
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Molecular cloning and expression of the gene encoding a phospholipase A1 from Aspergillus oryzae by Watanabe, I. (Sankyo Co. Ltd., Tokyo (Japan). Central Research Lab.), Koishi, R, Yao, Y, Tsuji, T, Serizawa, N

“…Phospholipase A1 (PLA1) is a hydrolytic enzyme that catalyzes removal of the acyl group from position 1 of lecithin to form lysolecithin. The genomic DNA and…”
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Microbial hydroxylation of ML-236B (compactin) and monacolin K (MB-530B) by Serizawa, N, Nakagawa, K, Hamano, K, Tsujita, Y, Terahara, A, Kuwano, H

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Secretion and overproduction of carboxypeptidase Y by a Saccharomyces cerevisiae ssl1 mutant strain by Ichikawa, K. (Sankyo Co. Ltd., Tanashi, Tokyo (Japan). Fermentation Research Lab.), Shiba, Y, Jigami, Y, Serizawa, N

“…Carboxypeptidase Y (CPY; EC 3.4.16.1) is the yeast vacuolar protease. To have CPY secreted and to increase its secretion level, we tried to express the…”
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Cloning and sequencing of the 3-phosphoglycerate kinase (PGK) gene from Penicillium citrinum and its application to heterologous gene expression by NARA, F, WATANABE, I, SERIZAWA, N

“…The gene coding for 3-phosphoglycerate kinase (PGK) in ML-236B (compactin)-producing Penicillium citrinum was isolated from the recombinant phage lambda…”
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