Search Results - "Serim, Sevnur"

Bioorthogonal metabolic glycoengineering of human larynx carcinoma (HEp-2) cells targeting sialic acid by Homann, Arne, Qamar, Riaz-Ul, Serim, Sevnur, Dersch, Petra, Seibel, Jürgen

“…Sialic acids are located at the termini of mammalian cell-surface glycostructures, which participate in essential interaction processes including adhesion of…”
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Activity-Based Probes for the Study of Proteases: Recent Advances and Developments by Serim, Sevnur, Haedke, Ute, Verhelst, Steven H. L.

“…Proteases are important targets for the treatment of human disease. Several protease inhibitors have failed in clinical trials due to a lack of in vivo…”
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Mixed alkyl aryl phosphonate esters as quenched fluorescent activity-based probes for serine proteases by Serim, Sevnur, Baer, Philipp, Verhelst, Steven H L

“…Activity-based probes (ABPs) are powerful tools for the analysis of active enzyme species in whole proteomes, cells or animals. Quenched fluorescent ABPs…”
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Tuning activity-based probe selectivity for serine proteases by on-resin 'click' construction of peptide diphenyl phosphonates by Serim, Sevnur, Mayer, Susanne V, Verhelst, Steven H L

“…Activity-based probes (ABPs) are powerful tools for functional proteomics studies. Their selectivity can be influenced by modification of a recognition element…”
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